PubMed

(Pro)renin receptor-mediated signal transduction and tissue renin-angiotensin system contribute to diabetes-induced retinal inflammation.

Satofuka S, Ichihara A, Nagai N, Noda K, Ozawa Y, Fukamizu A, Tsubota K, Itoh H, Oike Y, Ishida S.

Diabetes. 2009 Jul;58(7):1625-33. Epub 2009 Apr 23.PMID: 19389828 [PubMed - indexed for MEDLINE]Related articlesFree article

(Pro)renin receptor promotes choroidal neovascularization by activating its signal transduction and tissue renin-angiotensin system.

Satofuka S, Ichihara A, Nagai N, Noda K, Ozawa Y, Fukamizu A, Tsubota K, Itoh H, Oike Y, Ishida S.

Am J Pathol. 2008 Dec;173(6):1911-8. Epub 2008 Oct 30.PMID: 18974301 [PubMed - indexed for MEDLINE]Related articlesFree article

Suppression of diabetes-induced retinal inflammation by blocking the angiotensin II type 1 receptor or its downstream nuclear factor-kappaB pathway.

Nagai N, Izumi-Nagai K, Oike Y, Koto T, Satofuka S, Ozawa Y, Yamashiro K, Inoue M, Tsubota K, Umezawa K, Ishida S.

Invest Ophthalmol Vis Sci. 2007 Sep;48(9):4342-50.PMID: 17724226 [PubMed - indexed for MEDLINE]Related articlesFree article

Role of nonproteolytically activated prorenin in pathologic, but not physiologic, retinal neovascularization.

Satofuka S, Ichihara A, Nagai N, Koto T, Shinoda H, Noda K, Ozawa Y, Inoue M, Tsubota K, Itoh H, Oike Y, Ishida S.

Invest Ophthalmol Vis Sci. 2007 Jan;48(1):422-9.PMID: 17197563 [PubMed - indexed for MEDLINE]Related articlesFree article

Suppression of ocular inflammation in endotoxin-induced uveitis by inhibiting nonproteolytic activation of prorenin.

Satofuka S, Ichihara A, Nagai N, Yamashiro K, Koto T, Shinoda H, Noda K, Ozawa Y, Inoue M, Tsubota K, Suzuki F, Oike Y, Ishida S.

Invest Ophthalmol Vis Sci. 2006 Jun;47(6):2686-92.PMID: 16723487 [PubMed - indexed for MEDLINE]Related articlesFree article

Suppression of ocular inflammation in endotoxin-induced uveitis by blocking the angiotensin II type 1 receptor.

Nagai N, Oike Y, Noda K, Urano T, Kubota Y, Ozawa Y, Shinoda H, Koto T, Shinoda K, Inoue M, Tsubota K, Yamashiro K, Suda T, Ishida S.

Invest Ophthalmol Vis Sci. 2005 Aug;46(8):2925-31.PMID: 16043867 [PubMed - indexed for MEDLINE]Related articlesFree article

Angiotensin II type 1 receptor signaling contributes to synaptophysin degradation and neuronal dysfunction in the diabetic retina.

Kurihara T, Ozawa Y, Nagai N, Shinoda K, Noda K, Imamura Y, Tsubota K, Okano H, Oike Y, Ishida S.

Diabetes. 2008 Aug;57(8):2191-8. Epub 2008 May 16.PMID: 18487452 [PubMed - indexed for MEDLINE]Related articlesFree article

[Lifestyle-related diseases and anti-aging ophthalmology: suppression of retinal and choroidal pathologies by inhibiting renin-angiotensin system and inflammation]

Ishida S.

Nippon Ganka Gakkai Zasshi. 2009 Mar;113(3):403-22; discussion 423. Review. Japanese. PMID: 19348185 [PubMed - indexed for MEDLINE]Related articles

Suppression of choroidal neovascularization by inhibiting angiotensin-converting enzyme: minimal role of bradykinin.

Nagai N, Oike Y, Izumi-Nagai K, Koto T, Satofuka S, Shinoda H, Noda K, Ozawa Y, Inoue M, Tsubota K, Ishida S.

Invest Ophthalmol Vis Sci. 2007 May;48(5):2321-6.PMID: 17460297 [PubMed - indexed for MEDLINE]Related articlesFree article

Selective suppression of pathologic, but not physiologic, retinal neovascularization by blocking the angiotensin II type 1 receptor.

Nagai N, Noda K, Urano T, Kubota Y, Shinoda H, Koto T, Shinoda K, Inoue M, Shiomi T, Ikeda E, Tsubota K, Suda T, Oike Y, Ishida S.

Invest Ophthalmol Vis Sci. 2005 Mar;46(3):1078-84.PMID: 15728568 [PubMed - indexed for MEDLINE]Related articlesFree article

Retinal vascular endothelial growth factor induces intercellular adhesion molecule-1 and endothelial nitric oxide synthase expression and initiates early diabetic retinal leukocyte adhesion in vivo.

Joussen AM, Poulaki V, Qin W, Kirchhof B, Mitsiades N, Wiegand SJ, Rudge J, Yancopoulos GD, Adamis AP.

Am J Pathol. 2002 Feb;160(2):501-9.PMID: 11839570 [PubMed - indexed for MEDLINE]Related articlesFree article

Role of angiotensin II in retinal leukostasis in the diabetic rat.

Chen P, Scicli GM, Guo M, Fenstermacher JD, Dahl D, Edwards PA, Scicli AG.

Exp Eye Res. 2006 Nov;83(5):1041-51. Epub 2006 Jul 5. Erratum in: Exp Eye Res. 2007 Nov;85(5):738. PMID: 16822509 [PubMed - indexed for MEDLINE]Related articles

An endothelin type A receptor antagonist reverses upregulated VEGF and ICAM-1 levels in streptozotocin-induced diabetic rat retina.

Masuzawa K, Goto K, Jesmin S, Maeda S, Miyauchi T, Kaji Y, Oshika T, Hori S.

Curr Eye Res. 2006 Jan;31(1):79-89.PMID: 16421022 [PubMed - indexed for MEDLINE]Related articles

(Pro)renin receptor-mediated activation of mitogen-activated protein kinases in human vascular smooth muscle cells.

Sakoda M, Ichihara A, Kaneshiro Y, Takemitsu T, Nakazato Y, Nabi AH, Nakagawa T, Suzuki F, Inagami T, Itoh H.

Hypertens Res. 2007 Nov;30(11):1139-46.PMID: 18250563 [PubMed - indexed for MEDLINE]Related articles

Effects of peroxisome proliferator-activated receptor gamma and its ligand on blood-retinal barrier in a streptozotocin-induced diabetic model.

Muranaka K, Yanagi Y, Tamaki Y, Usui T, Kubota N, Iriyama A, Terauchi Y, Kadowaki T, Araie M.

Invest Ophthalmol Vis Sci. 2006 Oct;47(10):4547-52.PMID: 17003451 [PubMed - indexed for MEDLINE]Related articlesFree article

Prorenin receptor blockade inhibits development of glomerulosclerosis in diabetic angiotensin II type 1a receptor-deficient mice.

Ichihara A, Suzuki F, Nakagawa T, Kaneshiro Y, Takemitsu T, Sakoda M, Nabi AH, Nishiyama A, Sugaya T, Hayashi M, Inagami T.

J Am Soc Nephrol. 2006 Jul;17(7):1950-61. Epub 2006 May 31.PMID: 16738017 [PubMed - indexed for MEDLINE]Related articlesFree article

Activated prorenin as a therapeutic target for diabetic nephropathy.

Ichihara A, Sakoda M, Mito-Kurauchi A, Itoh H.

Diabetes Res Clin Pract. 2008 Nov 13;82 Suppl 1:S63-6. Epub 2008 Oct 14. Review.PMID: 18922597 [PubMed - indexed for MEDLINE]Related articles

Angiotensin II type 1 receptor-mediated inflammation is required for choroidal neovascularization.

Nagai N, Oike Y, Izumi-Nagai K, Urano T, Kubota Y, Noda K, Ozawa Y, Inoue M, Tsubota K, Suda T, Ishida S.

Arterioscler Thromb Vasc Biol. 2006 Oct;26(10):2252-9. Epub 2006 Aug 3.PMID: 16888236 [PubMed - indexed for MEDLINE]Related articlesFree article

Suppression of diabetic retinopathy with angiopoietin-1.

Joussen AM, Poulaki V, Tsujikawa A, Qin W, Qaum T, Xu Q, Moromizato Y, Bursell SE, Wiegand SJ, Rudge J, Ioffe E, Yancopoulos GD, Adamis AP.

Am J Pathol. 2002 May;160(5):1683-93.PMID: 12000720 [PubMed - indexed for MEDLINE]Related articlesFree article

Roles for host and tumor angiotensin II type 1 receptor in tumor growth and tumor-associated angiogenesis.

Imai N, Hashimoto T, Kihara M, Yoshida S, Kawana I, Yazawa T, Kitamura H, Umemura S.

Lab Invest. 2007 Feb;87(2):189-98. Epub 2006 Dec 18.PMID: 17318197 [PubMed - indexed for MEDLINE]Related articlesFree article