Warning: The NCBI web site requires JavaScript to function. more...
Investigation on the role of nsSNPs in HNPCC genes--a bioinformatics approach.
Doss CG, Sethumadhavan R.
J Biomed Sci. 2009 Apr 24;16:42.
Related citations
Computational and structural analysis of deleterious functional SNPs in ARNT oncogene.
George Priya Doss C, Sethumadhavan R.
Interdiscip Sci. 2009 Sep;1(3):220-8. Epub 2009 Aug 7.
Pathogenicity of MSH2 missense mutations is typically associated with impaired repair capability of the mutated protein.
Ollila S, Sarantaus L, Kariola R, Chan P, Hampel H, Holinski-Feder E, Macrae F, Kohonen-Corish M, Gerdes AM, Peltomäki P, Mangold E, de la Chapelle A, Greenblatt M, Nyström M.
Gastroenterology. 2006 Nov;131(5):1408-17. Epub 2006 Aug 22.
Computational prediction of the effects of non-synonymous single nucleotide polymorphisms in human DNA repair genes.
Nakken S, Alseth I, Rognes T.
Neuroscience. 2007 Apr 14;145(4):1273-9. Epub 2006 Oct 19. Review.
A bioinformatics approach for the phenotype prediction of nonsynonymous single nucleotide polymorphisms in human cytochromes P450.
Wang LL, Li Y, Zhou SF.
Drug Metab Dispos. 2009 May;37(5):977-91. Epub 2009 Feb 9.
Functional analysis of HNPCC-related missense mutations in MSH2.
Lützen A, de Wind N, Georgijevic D, Nielsen FC, Rasmussen LJ.
Mutat Res. 2008 Oct 14;645(1-2):44-55. Epub 2008 Sep 4.
Prediction of deleterious functional effects of non-synonymous single nucleotide polymorphisms in human nuclear receptor genes using a bioinformatics approach.
Liu YH, Li CG, Zhou SF.
Drug Metab Lett. 2009 Dec;3(4):242-86.
In silico searching for disease-associated functional DNA variants.
Sethumadhavan R, Doss CG, Rajasekaran R.
Methods Mol Biol. 2011;760:239-50.
Computational identification and structural analysis of deleterious functional SNPs in MLL gene causing acute leukemia.
George Priya Doss C, Rajasekaran R, Sethumadhavan R.
Interdiscip Sci. 2010 Sep;2(3):247-55. Epub 2010 Jul 25.
Identification and structural comparison of deleterious mutations in nsSNPs of ABL1 gene in chronic myeloid leukemia: a bio-informatics study.
George Priya Doss C, Sudandiradoss C, Rajasekaran R, Purohit R, Ramanathan K, Sethumadhavan R.
J Biomed Inform. 2008 Aug;41(4):607-12. Epub 2007 Dec 31.
Impact of single nucleotide polymorphisms in HBB gene causing haemoglobinopathies: in silico analysis.
George Priya Doss C, Rao S.
N Biotechnol. 2009 Apr;25(4):214-9. Epub 2009 Jan 21.
Applications of computational algorithm tools to identify functional SNPs.
George Priya Doss C, Sudandiradoss C, Rajasekaran R, Choudhury P, Sinha P, Hota P, Batra UP, Rao S.
Funct Integr Genomics. 2008 Nov;8(4):309-16. Epub 2008 Jun 19. Review.
[Study on the germline mutation of MSH6 gene in Chinese hereditary nonpolyposis colorectal cancer pedigrees using PCR based sequencing].
Yan SY, Zhou XY, Cai SJ, Yu BH, Zhang TM, Li XM, Lu YM, Zhou HH, Mo SJ, Du X, Shi DR.
Zhonghua Yi Xue Yi Chuan Xue Za Zhi. 2007 Dec;24(6):640-5. Chinese.
A novel computational and structural analysis of nsSNPs in CFTR gene.
George Priya Doss C, Rajasekaran R, Sudandiradoss C, Ramanathan K, Purohit R, Sethumadhavan R.
Genomic Med. 2008 Jan;2(1-2):23-32. Epub 2008 May 14.
Accurate classification of MLH1/MSH2 missense variants with multivariate analysis of protein polymorphisms-mismatch repair (MAPP-MMR).
Chao EC, Velasquez JL, Witherspoon MS, Rozek LS, Peel D, Ng P, Gruber SB, Watson P, Rennert G, Anton-Culver H, Lynch H, Lipkin SM.
Hum Mutat. 2008 Jun;29(6):852-60.
Many amino acid substitution variants identified in DNA repair genes during human population screenings are predicted to impact protein function.
Xi T, Jones IM, Mohrenweiser HW.
Genomics. 2004 Jun;83(6):970-9.
Statistical geometry based prediction of nonsynonymous SNP functional effects using random forest and neuro-fuzzy classifiers.
Barenboim M, Masso M, Vaisman II, Jamison DC.
Proteins. 2008 Jun;71(4):1930-9.
Mouse SNP Miner: an annotated database of mouse functional single nucleotide polymorphisms.
Reuveni E, Ramensky VE, Gross C.
BMC Genomics. 2007 Jan 21;8:24.
Applications of computational algorithm tools to identify functional SNPs in cytokine genes.
Shen J, Deininger PL, Zhao H.
Cytokine. 2006 Jul;35(1-2):62-6. Epub 2006 Aug 17.
Mechanisms of pathogenicity in human MSH2 missense mutants.
Ollila S, Dermadi Bebek D, Jiricny J, Nyström M.
Hum Mutat. 2008 Nov;29(11):1355-63.
Filter your results:
Your browsing activity is empty.
Activity recording is turned off.
Turn recording back on