PubMed

Gene expression profiling in the synovium identifies a predictive signature of absence of response to adalimumab therapy in rheumatoid arthritis.

Badot V, Galant C, Nzeusseu Toukap A, Theate I, Maudoux AL, Van den Eynde BJ, Durez P, Houssiau FA, Lauwerys BR.

Arthritis Res Ther. 2009;11(2):R57. Epub 2009 Apr 23.PMID: 19389237 [PubMed - indexed for MEDLINE]Related articlesFree article

Effect of infliximab on mRNA expression profiles in synovial tissue of rheumatoid arthritis patients.

Lindberg J, af Klint E, Catrina AI, Nilsson P, Klareskog L, Ulfgren AK, Lundeberg J.

Arthritis Res Ther. 2006;8(6):R179.PMID: 17134501 [PubMed - indexed for MEDLINE]Related articlesFree article

Messenger ribonucleic acid expression profile in peripheral blood cells from RA patients following treatment with an anti-TNF-alpha monoclonal antibody, infliximab.

Sekiguchi N, Kawauchi S, Furuya T, Inaba N, Matsuda K, Ando S, Ogasawara M, Aburatani H, Kameda H, Amano K, Abe T, Ito S, Takeuchi T.

Rheumatology (Oxford). 2008 Jun;47(6):780-8. Epub 2008 Apr 3.PMID: 18388148 [PubMed - indexed for MEDLINE]Related articles

Systemic TNF blockade does not modulate synovial expression of the pro-inflammatory mediator HMGB1 in rheumatoid arthritis patients--a prospective clinical study.

Sundberg E, Grundtman C, Af Klint E, Lindberg J, Ernestam S, Ulfgren AK, Harris HE, Andersson U.

Arthritis Res Ther. 2008;10(2):R33. Epub 2008 Mar 17.PMID: 18346273 [PubMed - indexed for MEDLINE]Related articlesFree article

Clinical efficacy of infliximab plus methotrexate in DMARD naive and DMARD refractory rheumatoid arthritis is associated with decreased synovial expression of TNF alpha and IL18 but not CXCL12.

van Oosterhout M, Levarht EW, Sont JK, Huizinga TW, Toes RE, van Laar JM.

Ann Rheum Dis. 2005 Apr;64(4):537-43.PMID: 15769913 [PubMed - indexed for MEDLINE]Related articlesFree article

The clinical response to infliximab in rheumatoid arthritis is in part dependent on pretreatment tumour necrosis factor alpha expression in the synovium.

Wijbrandts CA, Dijkgraaf MG, Kraan MC, Vinkenoog M, Smeets TJ, Dinant H, Vos K, Lems WF, Wolbink GJ, Sijpkens D, Dijkmans BA, Tak PP.

Ann Rheum Dis. 2008 Aug;67(8):1139-44. Epub 2007 Nov 29.PMID: 18055470 [PubMed - indexed for MEDLINE]Related articlesFree article

Overexpression of synoviolin in peripheral blood and synoviocytes from rheumatoid arthritis patients and continued elevation in nonresponders to infliximab treatment.

Toh ML, Marotte H, Blond JL, Jhumka U, Eljaafari A, Mougin B, Miossec P.

Arthritis Rheum. 2006 Jul;54(7):2109-18.PMID: 16802346 [PubMed - indexed for MEDLINE]Related articlesFree article

The value of synovial cytokine expression in predicting the clinical response to TNF antagonist therapy (infliximab).

Buch MH, Reece RJ, Quinn MA, English A, Cunnane G, Henshaw K, Bingham SJ, Bejarano V, Isaacs J, Emery P.

Rheumatology (Oxford). 2008 Oct;47(10):1469-75. Epub 2008 Jul 26.PMID: 18660510 [PubMed - indexed for MEDLINE]Related articles

Synovial expression of IL-15 in rheumatoid arthritis is not influenced by blockade of tumour necrosis factor.

Ernestam S, af Klint E, Catrina AI, Sundberg E, Engström M, Klareskog L, Ulfgren AK.

Arthritis Res Ther. 2006;8(1):R18.PMID: 16507118 [PubMed - indexed for MEDLINE]Related articlesFree article

Modulatory effects of inflammation and therapy on GDF-5 expression in rheumatoid arthritis synovium.

Bramlage CP, Kaps C, Ungethüm U, Bramlage P, Koziolek M, Wessels J, Krenn V, Pruss A, Müller GA, Strutz F, Burmester GR, Häupl T.

Scand J Rheumatol. 2008 Nov-Dec;37(6):401-9.PMID: 18830904 [PubMed - indexed for MEDLINE]Related articles

Overlapping gene expression profiles in rheumatoid fibroblast-like synoviocytes induced by the proinflammatory cytokines interleukin-1 beta and tumor necrosis factor.

Taberner M, Scott KF, Weininger L, Mackay CR, Rolph MS.

Inflamm Res. 2005 Jan;54(1):10-6.PMID: 15723199 [PubMed - indexed for MEDLINE]Related articles

Responsiveness to anti-tumour necrosis factor alpha therapy is related to pre-treatment tissue inflammation levels in rheumatoid arthritis patients.

van der Pouw Kraan TC, Wijbrandts CA, van Baarsen LG, Rustenburg F, Baggen JM, Verweij CL, Tak PP.

Ann Rheum Dis. 2008 Apr;67(4):563-6. Epub 2007 Nov 27.PMID: 18042642 [PubMed - indexed for MEDLINE]Related articles

Proinflammatory cytokines synergistically enhance the production of chemokine ligand 20 (CCL20) from rheumatoid fibroblast-like synovial cells in vitro and serum CCL20 is reduced in vivo by biologic disease-modifying antirheumatic drugs.

Kawashiri SY, Kawakami A, Iwamoto N, Fujikawa K, Aramaki T, Tamai M, Arima K, Kamachi M, Yamasaki S, Nakamura H, Tsurumoto T, Kono M, Shindo H, Ida H, Origuchi T, Eguchi K.

J Rheumatol. 2009 Nov;36(11):2397-402. Epub 2009 Oct 1.PMID: 19797510 [PubMed - indexed for MEDLINE]Related articles

Protein biochip array technology for cytokine profiling predicts etanercept responsiveness in rheumatoid arthritis.

Fabre S, Dupuy AM, Dossat N, Guisset C, Cohen JD, Cristol JP, Daures JP, Jorgensen C.

Clin Exp Immunol. 2008 Aug;153(2):188-95. Epub 2008 Jun 18.PMID: 18549443 [PubMed - indexed for MEDLINE]Related articlesFree article

Interleukin (IL)-23 p19 expression induced by IL-1beta in human fibroblast-like synoviocytes with rheumatoid arthritis via active nuclear factor-kappaB and AP-1 dependent pathway.

Liu FL, Chen CH, Chu SJ, Chen JH, Lai JH, Sytwu HK, Chang DM.

Rheumatology (Oxford). 2007 Aug;46(8):1266-73. Epub 2007 Jun 14.PMID: 17569750 [PubMed - indexed for MEDLINE]Related articlesFree article

Pretreatment cytokine profiles of peripheral blood mononuclear cells and serum from patients with rheumatoid arthritis in different american college of rheumatology response groups to methotrexate.

Seitz M, Zwicker M, Villiger PM.

J Rheumatol. 2003 Jan;30(1):28-35.PMID: 12508386 [PubMed - indexed for MEDLINE]Related articles

Interleukin-17 gene expression in patients with rheumatoid arthritis.

Kohno M, Tsutsumi A, Matsui H, Sugihara M, Suzuki T, Mamura M, Goto D, Matsumoto I, Ito S, Suguro T, Sumida T.

Mod Rheumatol. 2008;18(1):15-22. Epub 2007 Dec 20.PMID: 18092129 [PubMed - indexed for MEDLINE]Related articles

TWEAK and its receptor Fn14 in the synovium of patients with rheumatoid arthritis compared to psoriatic arthritis and its response to tumour necrosis factor blockade.

van Kuijk AW, Wijbrandts CA, Vinkenoog M, Zheng TS, Reedquist KA, Tak PP.

Ann Rheum Dis. 2010 Jan;69(1):301-4. Epub .PMID: 19147618 [PubMed - indexed for MEDLINE]Related articlesFree article

Peripheral blood expression of nuclear factor-kappab-regulated genes is associated with rheumatoid arthritis disease activity and responds differentially to anti-tumor necrosis factor-alpha versus methotrexate.

Parker A, Izmailova ES, Narang J, Badola S, Le T, Roubenoff R, Ginsburg GS, Maier A, Coblyn JS, Shadick NA, Weinblatt ME.

J Rheumatol. 2007 Sep;34(9):1817-22. Epub 2007 Aug 1.PMID: 17696278 [PubMed - indexed for MEDLINE]Related articles

The relationship between synovial lymphocyte aggregates and the clinical response to infliximab in rheumatoid arthritis: a prospective study.

Klaasen R, Thurlings RM, Wijbrandts CA, van Kuijk AW, Baeten D, Gerlag DM, Tak PP.

Arthritis Rheum. 2009 Nov;60(11):3217-24.PMID: 19877042 [PubMed - indexed for MEDLINE]Related articles