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Lifestyle-induced metabolic inflexibility and accelerated ageing syndrome: insulin resistance, friend or foe?

Nunn AV, Bell JD, Guy GW.

Nutr Metab (Lond). 2009 Apr 16;6:16.PMID: 19371409 [PubMed - in process]Related articlesFree article

Endocannabinoids, FOXO and the metabolic syndrome: Redox, function and tipping point - The view from two systems.

Nunn AV, Guy GW, Bell JD.

Immunobiology. 2009 May 18. [Epub ahead of print]PMID: 19457573 [PubMed - as supplied by publisher]Related articles

The integration of lipid-sensing and anti-inflammatory effects: how the PPARs play a role in metabolic balance.

Nunn AV, Bell J, Barter P.

Nucl Recept. 2007 May 25;5(1):1.PMID: 17531095 [PubMed]Related articlesFree article

Caloric restriction and mitochondrial function in the ageing myocardium.

Rohrbach S, Niemann B, Abushouk AM, Holtz J.

Exp Gerontol. 2006 May;41(5):525-31. Epub 2006 Mar 27. Review.PMID: 16564664 [PubMed - indexed for MEDLINE]Related articles

Mitochondrial H2O2 emission and cellular redox state link excess fat intake to insulin resistance in both rodents and humans.

Anderson EJ, Lustig ME, Boyle KE, Woodlief TL, Kane DA, Lin CT, Price JW 3rd, Kang L, Rabinovitch PS, Szeto HH, Houmard JA, Cortright RN, Wasserman DH, Neufer PD.

J Clin Invest. 2009 Feb 2. pii: 37048. doi: 10.1172/JCI37048. [Epub ahead of print]PMID: 19188683 [PubMed - as supplied by publisher]Related articlesFree article

Relations between metabolic syndrome, oxidative stress and inflammation and cardiovascular disease.

Holvoet P.

Verh K Acad Geneeskd Belg. 2008;70(3):193-219. Review.PMID: 18669160 [PubMed - indexed for MEDLINE]Related articles

Mitochondria and diabetes. Genetic, biochemical, and clinical implications of the cellular energy circuit.

Gerbitz KD, Gempel K, Brdiczka D.

Diabetes. 1996 Feb;45(2):113-26. Review.PMID: 8549853 [PubMed - indexed for MEDLINE]Related articles

Mitochondrial oxidative stress and inflammation: an slalom to obesity and insulin resistance.

Martínez JA.

J Physiol Biochem. 2006 Dec;62(4):303-6. Review.PMID: 17615956 [PubMed - indexed for MEDLINE]Related articles

Hyperoxia exposure induced hormesis decreases mitochondrial superoxide radical levels via Ins/IGF-1 signaling pathway in a long-lived age-1 mutant of Caenorhabditis elegans.

Yanase S, Ishii N.

J Radiat Res (Tokyo). 2008 May;49(3):211-8. Epub 2008 Feb 16.PMID: 18285659 [PubMed - indexed for MEDLINE]Related articlesFree article

Effect of a short-term diet and exercise intervention on oxidative stress, inflammation, MMP-9, and monocyte chemotactic activity in men with metabolic syndrome factors.

Roberts CK, Won D, Pruthi S, Kurtovic S, Sindhu RK, Vaziri ND, Barnard RJ.

J Appl Physiol. 2006 May;100(5):1657-65. Epub 2005 Dec 15.PMID: 16357066 [PubMed - indexed for MEDLINE]Related articlesFree article

Insulin sensitizers may prevent metabolic inflammation.

Colca JR.

Biochem Pharmacol. 2006 Jul 14;72(2):125-31. Epub 2006 Feb 10.PMID: 16472781 [PubMed - indexed for MEDLINE]Related articles

Mitochondrial fitness and insulin sensitivity in humans.

Szendroedi J, Roden M.

Diabetologia. 2008 Dec;51(12):2155-67. Epub 2008 Sep 19. Review.PMID: 18802678 [PubMed - indexed for MEDLINE]Related articles

Redox regulation of cellular signalling.

Kamata H, Hirata H.

Cell Signal. 1999 Jan;11(1):1-14. Review.PMID: 10206339 [PubMed - indexed for MEDLINE]Related articles

Exercise and diet induced weight loss improves measures of oxidative stress and insulin sensitivity in adults with characteristics of the metabolic syndrome.

Rector RS, Warner SO, Liu Y, Hinton PS, Sun GY, Cox RH, Stump CS, Laughlin MH, Dellsperger KC, Thomas TR.

Am J Physiol Endocrinol Metab. 2007 Aug;293(2):E500-6. Epub 2007 May 1.PMID: 17473052 [PubMed - indexed for MEDLINE]Related articlesFree article

Does dietary fat influence insulin action?

Storlien LH, Kriketos AD, Jenkins AB, Baur LA, Pan DA, Tapsell LC, Calvert GD.

Ann N Y Acad Sci. 1997 Sep 20;827:287-301. Review.PMID: 9329762 [PubMed - indexed for MEDLINE]Related articles

Tracing the origins of "fetal origins" of adult diseases: programming by oxidative stress?

Luo ZC, Fraser WD, Julien P, Deal CL, Audibert F, Smith GN, Xiong X, Walker M.

Med Hypotheses. 2006;66(1):38-44. Epub 2005 Sep 27.PMID: 16198060 [PubMed - indexed for MEDLINE]Related articles

The protective role of exercise on stress system dysregulation and comorbidities.

Tsatsoulis A, Fountoulakis S.

Ann N Y Acad Sci. 2006 Nov;1083:196-213. Review.PMID: 17148741 [PubMed - indexed for MEDLINE]Related articles

Insulin resistance and inflammation in an evolutionary perspective: the contribution of cytokine genotype/phenotype to thriftiness.

Fernández-Real JM, Ricart W.

Diabetologia. 1999 Nov;42(11):1367-74. Review.PMID: 10550422 [PubMed - indexed for MEDLINE]Related articles

Mitochondrial UCP4 mediates an adaptive shift in energy metabolism and increases the resistance of neurons to metabolic and oxidative stress.

Liu D, Chan SL, de Souza-Pinto NC, Slevin JR, Wersto RP, Zhan M, Mustafa K, de Cabo R, Mattson MP.

Neuromolecular Med. 2006;8(3):389-414.PMID: 16775390 [PubMed - indexed for MEDLINE]Related articles

Insulin resistance is an evolutionarily conserved physiological mechanism at the cellular level for protection against increased oxidative stress.

Erol A.

Bioessays. 2007 Aug;29(8):811-8. Review.PMID: 17621670 [PubMed - indexed for MEDLINE]Related articles