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Ranirestat for the management of diabetic sensorimotor polyneuropathy.

Bril V, Hirose T, Tomioka S, Buchanan R; Ranirestat Study Group.

Diabetes Care. 2009 Jul;32(7):1256-60. Epub 2009 Apr 14.PMID: 19366965 [PubMed - indexed for MEDLINE]Related articlesFree article

Long-term effects of ranirestat (AS-3201) on peripheral nerve function in patients with diabetic sensorimotor polyneuropathy.

Bril V, Buchanan RA.

Diabetes Care. 2006 Jan;29(1):68-72.PMID: 16373898 [PubMed - indexed for MEDLINE]Related articlesFree article

Aldose reductase inhibition by AS-3201 in sural nerve from patients with diabetic sensorimotor polyneuropathy.

Bril V, Buchanan RA.

Diabetes Care. 2004 Oct;27(10):2369-75.PMID: 15451902 [PubMed - indexed for MEDLINE]Related articlesFree article

Treatment of diabetic polyneuropathy with the antioxidant thioctic acid (alpha-lipoic acid): a two year multicenter randomized double-blind placebo-controlled trial (ALADIN II). Alpha Lipoic Acid in Diabetic Neuropathy.

Reljanovic M, Reichel G, Rett K, Lobisch M, Schuette K, Möller W, Tritschler HJ, Mehnert H.

Free Radic Res. 1999 Sep;31(3):171-9.PMID: 10499773 [PubMed - indexed for MEDLINE]Related articles

Is ACE inhibition with lisinopril helpful in diabetic neuropathy?

Reja A, Tesfaye S, Harris ND, Ward JD.

Diabet Med. 1995 Apr;12(4):307-9.PMID: 7600744 [PubMed - indexed for MEDLINE]Related articles

A meta-analysis of trials on aldose reductase inhibitors in diabetic peripheral neuropathy. The Italian Study Group. The St. Vincent Declaration.

Nicolucci A, Carinci F, Cavaliere D, Scorpiglione N, Belfiglio M, Labbrozzi D, Mari E, Benedetti MM, Tognoni G, Liberati A.

Diabet Med. 1996 Dec;13(12):1017-26.PMID: 8973882 [PubMed - indexed for MEDLINE]Related articles

Glycemic control is related to the electrophysiologic severity of diabetic peripheral sensorimotor polyneuropathy.

Tkac I, Bril V.

Diabetes Care. 1998 Oct;21(10):1749-52.PMID: 9773742 [PubMed - indexed for MEDLINE]Related articlesFree article

Ranirestat (AS-3201), a potent aldose reductase inhibitor, reduces sorbitol levels and improves motor nerve conduction velocity in streptozotocin-diabetic rats.

Matsumoto T, Ono Y, Kurono M, Kuromiya A, Nakamura K, Bril V.

J Pharmacol Sci. 2008 Jul;107(3):231-7.PMID: 18635918 [PubMed - indexed for MEDLINE]Related articlesFree article

Clinical efficacy of fidarestat, a novel aldose reductase inhibitor, for diabetic peripheral neuropathy: a 52-week multicenter placebo-controlled double-blind parallel group study.

Hotta N, Toyota T, Matsuoka K, Shigeta Y, Kikkawa R, Kaneko T, Takahashi A, Sugimura K, Koike Y, Ishii J, Sakamoto N; SNK-860 Diabetic Neuropathy Study Group.

Diabetes Care. 2001 Oct;24(10):1776-82. Erratum in: Diabetes Care 2002 Feb;25(2):413-4. PMID: 11574441 [PubMed - indexed for MEDLINE]Related articlesFree article

Withdrawal of the aldose reductase inhibitor tolrestat in patients with diabetic neuropathy: effect on nerve function. The Tolrestat Study Group.

Santiago JV, Snksen PH, Boulton AJ, Macleod A, Beg M, Bochenek W, Graepel GJ, Gonen B.

J Diabetes Complications. 1993 Jul-Sep;7(3):170-8.PMID: 8343611 [PubMed - indexed for MEDLINE]Related articles

Acetyl-L-carnitine (levacecarnine) in the treatment of diabetic neuropathy. A long-term, randomised, double-blind, placebo-controlled study.

De Grandis D, Minardi C.

Drugs R D. 2002;3(4):223-31.PMID: 12455197 [PubMed - indexed for MEDLINE]Related articles

Clinical trials of sorbinil on nerve function.

Pfeifer MA.

Metabolism. 1986 Apr;35(4 Suppl 1):78-82.PMID: 3083211 [PubMed - indexed for MEDLINE]Related articles

Reproducibility of parameters for assessment of diabetic neuropathy. The French Group for Research and Study of Diabetic Neuropathy.

Valensi P, Attali JR, Gagant S.

Diabet Med. 1993 Dec;10(10):933-9.PMID: 8306589 [PubMed - indexed for MEDLINE]Related articles

Long-term treatment with ranirestat (AS-3201), a potent aldose reductase inhibitor, suppresses diabetic neuropathy and cataract formation in rats.

Matsumoto T, Ono Y, Kuromiya A, Toyosawa K, Ueda Y, Bril V.

J Pharmacol Sci. 2008 Jul;107(3):340-8. Epub 2008 Jul 8.PMID: 18612195 [PubMed - indexed for MEDLINE]Related articlesFree article

Effect of aldose reductase inhibition on nerve conduction and morphometry in diabetic neuropathy. Zenarestat Study Group.

Greene DA, Arezzo JC, Brown MB.

Neurology. 1999 Aug 11;53(3):580-91. Erratum in: Neurology 2001 Apr 24;56(8):1124. PMID: 10449124 [PubMed - indexed for MEDLINE]Related articles

Natural progression of diabetic peripheral neuropathy in the Zenarestat study population.

Brown MJ, Bird SJ, Watling S, Kaleta H, Hayes L, Eckert S, Foyt HL; Zenarest study.

Diabetes Care. 2004 May;27(5):1153-9.PMID: 15111537 [PubMed - indexed for MEDLINE]Related articlesFree article

Aldose reductase inhibition improves nerve conduction velocity in diabetic patients.

Judzewitsch RG, Jaspan JB, Polonsky KS, Weinberg CR, Halter JB, Halar E, Pfeifer MA, Vukadinovic C, Bernstein L, Schneider M, Liang KY, Gabbay KH, Rubenstein AH, Porte D Jr.

N Engl J Med. 1983 Jan 20;308(3):119-25.PMID: 6401351 [PubMed - indexed for MEDLINE]Related articles

Efficacy and safety of pregabalin 600 mg/d for treating painful diabetic peripheral neuropathy: a double-blind placebo-controlled trial.

Arezzo JC, Rosenstock J, Lamoreaux L, Pauer L.

BMC Neurol. 2008 Sep 16;8:33.PMID: 18796160 [PubMed - indexed for MEDLINE]Related articlesFree article

The efficacy of tolrestat in the treatment of diabetic peripheral neuropathy. A meta-analysis of individual patient data.

Nicolucci A, Carinci F, Graepel JG, Hohman TC, Ferris F, Lachin JM.

Diabetes Care. 1996 Oct;19(10):1091-6.PMID: 8886554 [PubMed - indexed for MEDLINE]Related articles

Effect of hyperglycemia and the aldose reductase inhibitor tolrestat on sural nerve biochemistry and morphometry in advanced diabetic peripheral polyneuropathy. The Tolrestat Study Group.

Sima AA, Greene DA, Brown MB, Hohman TC, Hicks D, Graepel GJ, Bochenek WJ, Beg M, Gonen B.

J Diabetes Complications. 1993 Jul-Sep;7(3):157-69.PMID: 8343610 [PubMed - indexed for MEDLINE]Related articles