PubMed

Loss of TGF-beta or Wnt5a results in an increase in Wnt/beta-catenin activity and redirects mammary tumour phenotype.

Roarty K, Baxley SE, Crowley MR, Frost AR, Serra R.

Breast Cancer Res. 2009;11(2):R19. Epub 2009 Apr 3.PMID: 19344510 [PubMed - indexed for MEDLINE]Related articlesFree article

Wnt5a is required for proper mammary gland development and TGF-beta-mediated inhibition of ductal growth.

Roarty K, Serra R.

Development. 2007 Nov;134(21):3929-39. Epub 2007 Sep 26.PMID: 17898001 [PubMed - indexed for MEDLINE]Related articlesFree article

Wnt-1 and int-2 mammary oncogene effects on the beta-catenin pathway in immortalized mouse mammary epithelial cells are not sufficient for tumorigenesis.

Hollmann CA, Kittrell FS, Medina D, Butel JS.

Oncogene. 2001 Nov 15;20(52):7645-57.PMID: 11753642 [PubMed - indexed for MEDLINE]Related articlesFree article

Transcriptional cooperation between the transforming growth factor-beta and Wnt pathways in mammary and intestinal tumorigenesis.

Labbé E, Lock L, Letamendia A, Gorska AE, Gryfe R, Gallinger S, Moses HL, Attisano L.

Cancer Res. 2007 Jan 1;67(1):75-84.PMID: 17210685 [PubMed - indexed for MEDLINE]Related articlesFree article

Stromal transforming growth factor-beta signaling mediates prostatic response to androgen ablation by paracrine Wnt activity.

Placencio VR, Sharif-Afshar AR, Li X, Huang H, Uwamariya C, Neilson EG, Shen MM, Matusik RJ, Hayward SW, Bhowmick NA.

Cancer Res. 2008 Jun 15;68(12):4709-18.PMID: 18559517 [PubMed - indexed for MEDLINE]Related articlesFree article

Overexpression of a kinase-deficient transforming growth factor-beta type II receptor in mouse mammary stroma results in increased epithelial branching.

Joseph H, Gorska AE, Sohn P, Moses HL, Serra R.

Mol Biol Cell. 1999 Apr;10(4):1221-34.PMID: 10198068 [PubMed - indexed for MEDLINE]Related articlesFree article

Targeted activation of beta-catenin signaling in basal mammary epithelial cells affects mammary development and leads to hyperplasia.

Teulière J, Faraldo MM, Deugnier MA, Shtutman M, Ben-Ze'ev A, Thiery JP, Glukhova MA.

Development. 2005 Jan;132(2):267-77. Epub 2004 Dec 8.PMID: 15590737 [PubMed - indexed for MEDLINE]Related articlesFree article

Transgenic mice expressing a dominant-negative mutant type II transforming growth factor-beta receptor exhibit impaired mammary development and enhanced mammary tumor formation.

Gorska AE, Jensen RA, Shyr Y, Aakre ME, Bhowmick NA, Moses HL.

Am J Pathol. 2003 Oct;163(4):1539-49.PMID: 14507660 [PubMed - indexed for MEDLINE]Related articlesFree article

Autocrine WNT signaling contributes to breast cancer cell proliferation via the canonical WNT pathway and EGFR transactivation.

Schlange T, Matsuda Y, Lienhard S, Huber A, Hynes NE.

Breast Cancer Res. 2007;9(5):R63.PMID: 17897439 [PubMed - indexed for MEDLINE]Related articlesFree article

Transforming growth factor-beta signaling helps specify tumor type in DMBA and hormone-induced mammary cancers.

Crowley MR, Frost A, Chen DT, Baffi MO, Nicola T, Serra R.

Differentiation. 2006 Feb;74(1):40-52.PMID: 16466399 [PubMed - indexed for MEDLINE]Related articles

Redundant expression of canonical Wnt ligands in human breast cancer cell lines.

Benhaj K, Akcali KC, Ozturk M.

Oncol Rep. 2006 Mar;15(3):701-7.PMID: 16465433 [PubMed - indexed for MEDLINE]Related articles

Receptor and secreted targets of Wnt-1/beta-catenin signalling in mouse mammary epithelial cells.

Kenny PA, Enver T, Ashworth A.

BMC Cancer. 2005 Jan 10;5:3.PMID: 15642117 [PubMed - indexed for MEDLINE]Related articlesFree article

Effect of conditional knockout of the type II TGF-beta receptor gene in mammary epithelia on mammary gland development and polyomavirus middle T antigen induced tumor formation and metastasis.

Forrester E, Chytil A, Bierie B, Aakre M, Gorska AE, Sharif-Afshar AR, Muller WJ, Moses HL.

Cancer Res. 2005 Mar 15;65(6):2296-302.PMID: 15781643 [PubMed - indexed for MEDLINE]Related articlesFree article

Overexpression of the tumor suppressor gene phosphatase and tensin homologue partially inhibits wnt-1-induced mammary tumorigenesis.

Zhao H, Cui Y, Dupont J, Sun H, Hennighausen L, Yakar S.

Cancer Res. 2005 Aug 1;65(15):6864-73.PMID: 16061670 [PubMed - indexed for MEDLINE]Related articlesFree article

Cooperation between TGF-beta and Wnt pathways during chondrocyte and adipocyte differentiation of human marrow stromal cells.

Zhou S, Eid K, Glowacki J.

J Bone Miner Res. 2004 Mar;19(3):463-70. Epub 2003 Dec 22.PMID: 15040835 [PubMed - indexed for MEDLINE]Related articles

Dominant-negative interference of the transforming growth factor beta type II receptor in mammary gland epithelium results in alveolar hyperplasia and differentiation in virgin mice.

Gorska AE, Joseph H, Derynck R, Moses HL, Serra R.

Cell Growth Differ. 1998 Mar;9(3):229-38.PMID: 9543389 [PubMed - indexed for MEDLINE]Related articlesFree article

Orphan nuclear receptor TLX activates Wnt/beta-catenin signalling to stimulate neural stem cell proliferation and self-renewal.

Qu Q, Sun G, Li W, Yang S, Ye P, Zhao C, Yu RT, Gage FH, Evans RM, Shi Y.

Nat Cell Biol. 2010 Jan;12(1):31-40; sup pp 1-9. Epub 2009 Dec 13.PMID: 20010817 [PubMed - indexed for MEDLINE]Related articles

Prolactin and transforming growth factor-beta signaling exert opposing effects on mammary gland morphogenesis, involution, and the Akt-forkhead pathway.

Bailey JP, Nieport KM, Herbst MP, Srivastava S, Serra RA, Horseman ND.

Mol Endocrinol. 2004 May;18(5):1171-84. Epub 2004 Feb 12.PMID: 14963111 [PubMed - indexed for MEDLINE]Related articlesFree article

Essential roles of mesenchyme-derived beta-catenin in mouse Müllerian duct morphogenesis.

Deutscher E, Hung-Chang Yao H.

Dev Biol. 2007 Jul 15;307(2):227-36. Epub 2007 May 3.PMID: 17532316 [PubMed - indexed for MEDLINE]Related articlesFree article

Latent transforming growth factor-beta activation in mammary gland: regulation by ovarian hormones affects ductal and alveolar proliferation.

Ewan KB, Shyamala G, Ravani SA, Tang Y, Akhurst R, Wakefield L, Barcellos-Hoff MH.

Am J Pathol. 2002 Jun;160(6):2081-93.PMID: 12057913 [PubMed - indexed for MEDLINE]Related articlesFree article