Warning: The NCBI web site requires JavaScript to function. more...
Asporin, a susceptibility gene in osteoarthritis, is expressed at higher levels in the more degenerate human intervertebral disc.
Gruber HE, Ingram JA, Hoelscher GL, Zinchenko N, Hanley EN Jr, Sun Y.
Arthritis Res Ther. 2009;11(2):R47. Epub 2009 Mar 27.
Related citations
Immunolocalization and biochemical evidence of pregnancy-associated plasma protein A in the intervertebral disc.
Gruber HE, Hoelscher G, Ingram JA, Hanley EN Jr.
Spine (Phila Pa 1976). 2008 Jun 15;33(14):E447-54.
Annulus cells from more degenerated human discs show modified gene expression in 3D culture compared with expression in cells from healthier discs.
Gruber HE, Hoelscher GL, Hanley EN Jr.
Spine J. 2010 Aug;10(8):721-7.
Senescence in cells of the aging and degenerating intervertebral disc: immunolocalization of senescence-associated beta-galactosidase in human and sand rat discs.
Gruber HE, Ingram JA, Norton HJ, Hanley EN Jr.
Spine (Phila Pa 1976). 2007 Feb 1;32(3):321-7.
Immunolocalization of thrombospondin in the human and sand rat intervertebral disc.
Gruber HE, Ingram JA, Hanley EN Jr.
Spine (Phila Pa 1976). 2006 Oct 15;31(22):2556-61.
Prostaglandin E1 and misoprostol increase epidermal growth factor production in 3D-cultured human annulus cells.
Gruber HE, Hoelscher G, Loeffler B, Chow Y, Ingram JA, Halligan W, Hanley EN Jr.
Spine J. 2009 Sep;9(9):760-6. Epub 2009 Jun 16.
Association of the asporin D14 allele with lumbar-disc degeneration in Asians.
Song YQ, Cheung KM, Ho DW, Poon SC, Chiba K, Kawaguchi Y, Hirose Y, Alini M, Grad S, Yee AF, Leong JC, Luk KD, Yip SP, Karppinen J, Cheah KS, Sham P, Ikegawa S, Chan D.
Am J Hum Genet. 2008 Mar;82(3):744-7. Epub 2008 Feb 21.
Microarray analysis of laser capture microdissected-anulus cells from the human intervertebral disc.
Gruber HE, Mougeot JL, Hoelscher G, Ingram JA, Hanley EN Jr.
Spine (Phila Pa 1976). 2007 May 15;32(11):1181-7.
The SOX9 transcription factor in the human disc: decreased immunolocalization with age and disc degeneration.
Gruber HE, Norton HJ, Ingram JA, Hanley EN Jr.
Spine (Phila Pa 1976). 2005 Mar 15;30(6):625-30.
Brain-derived neurotrophic factor and its receptor in the human and the sand rat intervertebral disc.
Gruber HE, Ingram JA, Hoelscher G, Zinchenko N, Norton HJ, Hanley EN Jr.
Arthritis Res Ther. 2008;10(4):R82. Epub 2008 Jul 17.
Increased cell senescence is associated with decreased cell proliferation in vivo in the degenerating human annulus.
Gruber HE, Ingram JA, Davis DE, Hanley EN Jr.
Spine J. 2009 Mar;9(3):210-5. Epub 2008 Apr 25.
Immunolocalization of MMP-19 in the human intervertebral disc: implications for disc aging and degeneration.
Biotech Histochem. 2005 May-Aug;80(3-4):157-62.
Periostin is expressed by cells of the human and sand rat intervertebral discs.
Gruber HE, Norris RA, Kern MJ, Hoelscher GL, Ingram JA, Zinchenko N, Hanley EN Jr.
Biotech Histochem. 2011 Jun;86(3):199-206. Epub 2010 Apr 6.
Expression and distribution of tumor necrosis factor alpha in human lumbar intervertebral discs: a study in surgical specimen and autopsy controls.
Weiler C, Nerlich AG, Bachmeier BE, Boos N.
Spine (Phila Pa 1976). 2005 Jan 1;30(1):44-53; discussion 54.
Cellular, but not matrix, immunolocalization of SPARC in the human intervertebral disc: decreasing localization with aging and disc degeneration.
Gruber HE, Ingram JA, Leslie K, Hanley EN Jr.
Spine (Phila Pa 1976). 2004 Oct 15;29(20):2223-8.
Gene expression of types I, II, and VI collagen, aggrecan, and chondroitin-6-sulfotransferase in the human annulus: in situ hybridization findings.
Gruber HE, Ingram J, Leslie K, Hanley EN Jr.
Spine J. 2008 Sep-Oct;8(5):810-7. Epub 2007 Nov 19.
Colony formation and matrix production by human anulus cells: modulation in three-dimensional culture.
Gruber HE, Leslie K, Ingram J, Hoelscher G, Norton HJ, Hanley EN Jr.
Spine (Phila Pa 1976). 2004 Jul 1;29(13):E267-74.
Cell polarity in the anulus of the human intervertebral disc: morphologic, immunocytochemical, and molecular evidence.
Gruber HE, Ingram J, Hoelscher GL, Norton HJ, Hanley EN Jr.
Spine (Phila Pa 1976). 2007 May 20;32(12):1287-94.
Human disc degeneration is associated with increased MMP 7 expression.
Le Maitre CL, Freemont AJ, Hoyland JA.
Biotech Histochem. 2006 Jul-Dec;81(4-6):125-31.
Analysis of cell death and vertebral end plate bone mineral density in the annulus of the aging sand rat.
Gruber HE, Gordon B, Norton HJ, Kilburn J, Williams C, Zinchenko N, Heath J, Ingram J, Hanley EN Jr.
Spine J. 2008 May-Jun;8(3):475-81. Epub 2007 Feb 5.
Filter your results:
Your browsing activity is empty.
Activity recording is turned off.
Turn recording back on