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    Results: 1 to 20 of 141

    1.

    G-allele of intronic rs10830963 in MTNR1B confers increased risk of impaired fasting glycemia and type 2 diabetes through an impaired glucose-stimulated insulin release: studies involving 19,605 Europeans.

    Sparsø T, Bonnefond A, Andersson E, Bouatia-Naji N, Holmkvist J, Wegner L, Grarup N, Gjesing AP, Banasik K, Cavalcanti-Proença C, Marchand M, Vaxillaire M, Charpentier G, Jarvelin MR, Tichet J, Balkau B, Marre M, Lévy-Marchal C, Faerch K, Borch-Johnsen K, Jørgensen T, Madsbad S, Poulsen P, Vaag A, Dina C, Hansen T, Pedersen O, Froguel P.

    Diabetes. 2009 Jun;58(6):1450-6. Epub 2009 Mar 26.PMID: 19324940 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    Polymorphisms within the novel type 2 diabetes risk locus MTNR1B determine beta-cell function.

    Staiger H, Machicao F, Schäfer SA, Kirchhoff K, Kantartzis K, Guthoff M, Silbernagel G, Stefan N, Häring HU, Fritsche A.

    PLoS One. 2008;3(12):e3962. Epub 2008 Dec 17.PMID: 19088850 [PubMed - indexed for MEDLINE]Related articlesFree article

    3.

    Studies of association of variants near the HHEX, CDKN2A/B, and IGF2BP2 genes with type 2 diabetes and impaired insulin release in 10,705 Danish subjects: validation and extension of genome-wide association studies.

    Grarup N, Rose CS, Andersson EA, Andersen G, Nielsen AL, Albrechtsen A, Clausen JO, Rasmussen SS, Jørgensen T, Sandbaek A, Lauritzen T, Schmitz O, Hansen T, Pedersen O.

    Diabetes. 2007 Dec;56(12):3105-11. Epub 2007 Sep 7.PMID: 17827400 [PubMed - indexed for MEDLINE]Related articlesFree article

    4.

    Common genetic variation in the melatonin receptor 1B gene (MTNR1B) is associated with decreased early-phase insulin response.

    Langenberg C, Pascoe L, Mari A, Tura A, Laakso M, Frayling TM, Barroso I, Loos RJ, Wareham NJ, Walker M; RISC Consortium.

    Diabetologia. 2009 Aug;52(8):1537-42. Epub 2009 May 20.PMID: 19455304 [PubMed - indexed for MEDLINE]Related articles

    5.

    A common variant in MTNR1B, encoding melatonin receptor 1B, is associated with type 2 diabetes and fasting plasma glucose in Han Chinese individuals.

    Rönn T, Wen J, Yang Z, Lu B, Du Y, Groop L, Hu R, Ling C.

    Diabetologia. 2009 May;52(5):830-3. Epub 2009 Feb 25.PMID: 19241057 [PubMed - indexed for MEDLINE]Related articles

    6.

    A variant in the G6PC2/ABCB11 locus is associated with increased fasting plasma glucose, increased basal hepatic glucose production and increased insulin release after oral and intravenous glucose loads.

    Rose CS, Grarup N, Krarup NT, Poulsen P, Wegner L, Nielsen T, Banasik K, Faerch K, Andersen G, Albrechtsen A, Borch-Johnsen K, Clausen JO, Jørgensen T, Vaag A, Pedersen O, Hansen T.

    Diabetologia. 2009 Oct;52(10):2122-9. Epub 2009 Aug 8.PMID: 19669124 [PubMed - in process]Related articles

    7.

    Association of variants in the sterol regulatory element-binding factor 1 (SREBF1) gene with type 2 diabetes, glycemia, and insulin resistance: a study of 15,734 Danish subjects.

    Grarup N, Stender-Petersen KL, Andersson EA, Jørgensen T, Borch-Johnsen K, Sandbaek A, Lauritzen T, Schmitz O, Hansen T, Pedersen O.

    Diabetes. 2008 Apr;57(4):1136-42. Epub 2008 Jan 11.PMID: 18192539 [PubMed - indexed for MEDLINE]Related articlesFree article

    8.

    The K121Q variant of the human PC-1 gene is not associated with insulin resistance or type 2 diabetes among Danish Caucasians.

    Rasmussen SK, Urhammer SA, Pizzuti A, Echwald SM, Ekstrøm CT, Hansen L, Hansen T, Borch-Johnsen K, Frittitta L, Trischitta V, Pedersen O.

    Diabetes. 2000 Sep;49(9):1608-11.PMID: 10969849 [PubMed - indexed for MEDLINE]Related articlesFree article

    9.

    Studies of the relationship between the ENPP1 K121Q polymorphism and type 2 diabetes, insulin resistance and obesity in 7,333 Danish white subjects.

    Grarup N, Urhammer SA, Ek J, Albrechtsen A, Glümer C, Borch-Johnsen K, Jørgensen T, Hansen T, Pedersen O.

    Diabetologia. 2006 Sep;49(9):2097-104. Epub 2006 Jul 25.PMID: 16865358 [PubMed - indexed for MEDLINE]Related articles

    10.

    [The relation between fasting plasma glucose concentrations and insulin resistance]

    Li L, Wang GX, Li P, Shang XJ, Liu C, Wang YJ, Yue GY.

    Zhonghua Nei Ke Za Zhi. 2005 Oct;44(10):755-8. Chinese. PMID: 16255885 [PubMed - indexed for MEDLINE]Related articles

    11.

    Genetic variation in KCNQ1 associates with fasting glucose and beta-cell function: a study of 3,734 subjects comprising three ethnicities living in Singapore.

    Tan JT, Nurbaya S, Gardner D, Ye S, Tai ES, Ng DP.

    Diabetes. 2009 Jun;58(6):1445-9. Epub 2009 Feb 27.PMID: 19252135 [PubMed - indexed for MEDLINE]Related articlesFree article

    12.

    Variants in MTNR1B influence fasting glucose levels.

    Prokopenko I, Langenberg C, Florez JC, Saxena R, Soranzo N, Thorleifsson G, Loos RJ, Manning AK, Jackson AU, Aulchenko Y, Potter SC, Erdos MR, Sanna S, Hottenga JJ, Wheeler E, Kaakinen M, Lyssenko V, Chen WM, Ahmadi K, Beckmann JS, Bergman RN, Bochud M, Bonnycastle LL, Buchanan TA, Cao A, Cervino A, Coin L, Collins FS, Crisponi L, de Geus EJ, Dehghan A, Deloukas P, Doney AS, Elliott P, Freimer N, Gateva V, Herder C, Hofman A, Hughes TE, Hunt S, Illig T, Inouye M, Isomaa B, Johnson T, Kong A, Krestyaninova M, Kuusisto J, Laakso M, Lim N, Lindblad U, Lindgren CM, McCann OT, Mohlke KL, Morris AD, Naitza S, Orrù M, Palmer CN, Pouta A, Randall J, Rathmann W, Saramies J, Scheet P, Scott LJ, Scuteri A, Sharp S, Sijbrands E, Smit JH, Song K, Steinthorsdottir V, Stringham HM, Tuomi T, Tuomilehto J, Uitterlinden AG, Voight BF, Waterworth D, Wichmann HE, Willemsen G, Witteman JC, Yuan X, Zhao JH, Zeggini E, Schlessinger D, Sandhu M, Boomsma DI, Uda M, Spector TD, Penninx BW, Altshuler D, Vollenweider P, Jarvelin MR, Lakatta E, Waeber G, Fox CS, Peltonen L, Groop LC, Mooser V, Cupples LA, Thorsteinsdottir U, Boehnke M, Barroso I, Van Duijn C, Dupuis J, Watanabe RM, Stefansson K, McCarthy MI, Wareham NJ, Meigs JB, Abecasis GR.

    Nat Genet. 2009 Jan;41(1):77-81. Epub 2008 Dec 7.PMID: 19060907 [PubMed - indexed for MEDLINE]Related articles

    13.

    Association of common genetic variation in the FOXO1 gene with beta-cell dysfunction, impaired glucose tolerance, and type 2 diabetes.

    Müssig K, Staiger H, Machicao F, Stancáková A, Kuusisto J, Laakso M, Thamer C, Machann J, Schick F, Claussen CD, Stefan N, Fritsche A, Häring HU.

    J Clin Endocrinol Metab. 2009 Apr;94(4):1353-60. Epub 2009 Jan 13.PMID: 19141580 [PubMed - indexed for MEDLINE]Related articles

    14.

    Association testing of novel type 2 diabetes risk alleles in the JAZF1, CDC123/CAMK1D, TSPAN8, THADA, ADAMTS9, and NOTCH2 loci with insulin release, insulin sensitivity, and obesity in a population-based sample of 4,516 glucose-tolerant middle-aged Danes.

    Grarup N, Andersen G, Krarup NT, Albrechtsen A, Schmitz O, Jørgensen T, Borch-Johnsen K, Hansen T, Pedersen O.

    Diabetes. 2008 Sep;57(9):2534-40. Epub 2008 Jun 20.PMID: 18567820 [PubMed - indexed for MEDLINE]Related articlesFree article

    15.

    Insulin secretion and insulin sensitivity pattern is different in isolated impaired glucose tolerance and impaired fasting glucose: the risk factor in Impaired Glucose Tolerance for Atherosclerosis and Diabetes study.

    Hanefeld M, Koehler C, Fuecker K, Henkel E, Schaper F, Temelkova-Kurktschiev T; Impaired Glucose Tolerance for Atherosclerosis and Diabetes study.

    Diabetes Care. 2003 Mar;26(3):868-74.PMID: 12610051 [PubMed - indexed for MEDLINE]Related articlesFree article

    16.

    A variant near MTNR1B is associated with increased fasting plasma glucose levels and type 2 diabetes risk.

    Bouatia-Naji N, Bonnefond A, Cavalcanti-Proença C, Sparsø T, Holmkvist J, Marchand M, Delplanque J, Lobbens S, Rocheleau G, Durand E, De Graeve F, Chèvre JC, Borch-Johnsen K, Hartikainen AL, Ruokonen A, Tichet J, Marre M, Weill J, Heude B, Tauber M, Lemaire K, Schuit F, Elliott P, Jørgensen T, Charpentier G, Hadjadj S, Cauchi S, Vaxillaire M, Sladek R, Visvikis-Siest S, Balkau B, Lévy-Marchal C, Pattou F, Meyre D, Blakemore AI, Jarvelin MR, Walley AJ, Hansen T, Dina C, Pedersen O, Froguel P.

    Nat Genet. 2009 Jan;41(1):89-94. Epub 2008 Dec 7.PMID: 19060909 [PubMed - indexed for MEDLINE]Related articles

    17.

    Beta-cell dysfunction in subjects with impaired glucose tolerance and early type 2 diabetes: comparison of surrogate markers with first-phase insulin secretion from an intravenous glucose tolerance test.

    Festa A, Williams K, Hanley AJ, Haffner SM.

    Diabetes. 2008 Jun;57(6):1638-44. Epub 2008 Mar 10.PMID: 18332099 [PubMed - indexed for MEDLINE]Related articlesFree article

    18.

    The common P446L polymorphism in GCKR inversely modulates fasting glucose and triglyceride levels and reduces type 2 diabetes risk in the DESIR prospective general French population.

    Vaxillaire M, Cavalcanti-Proença C, Dechaume A, Tichet J, Marre M, Balkau B, Froguel P; DESIR Study Group.

    Diabetes. 2008 Aug;57(8):2253-7. Epub 2008 Jun 12.PMID: 18556336 [PubMed - indexed for MEDLINE]Related articlesFree article

    19.

    Insulin resistance, beta cell function and cardiovascular risk factors in Ghanaians with varying degrees of glucose tolerance.

    Amoah AG, Schuster DP, Gaillard T, Osei K.

    Ethn Dis. 2002 Fall;12(4):S3-10-7.PMID: 12477148 [PubMed - indexed for MEDLINE]Related articles

    20.

    Changes in insulin sensitivity and insulin release in relation to glycemia and glucose tolerance in 6,414 Finnish men.

    Stancáková A, Javorský M, Kuulasmaa T, Haffner SM, Kuusisto J, Laakso M.

    Diabetes. 2009 May;58(5):1212-21. Epub 2009 Feb 17.PMID: 19223598 [PubMed - indexed for MEDLINE]Related articlesFree article

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