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Positional effect of mutations in 5'UTR of hepatitis C virus 4a on patients' response to therapy.

El Awady MK, Azzazy HM, Fahmy AM, Shawky SM, Badreldin NG, Yossef SS, Omran MH, Zekri AR, Goueli SA.

World J Gastroenterol. 2009 Mar 28;15(12):1480-6.PMID: 19322922 [PubMed - indexed for MEDLINE]Related articlesFree article

Quasispecies heterogeneity and constraints on the evolution of the 5' noncoding region of hepatitis C virus (HCV): relationship with HCV resistance to interferon-alpha therapy.

Soler M, Pellerin M, Malnou CE, Dhumeaux D, Kean KM, Pawlotsky JM.

Virology. 2002 Jun 20;298(1):160-73.PMID: 12093183 [PubMed - indexed for MEDLINE]Related articles

Association with 5'-untranslated region and response to interferon in chronic hepatitis C.

Katano Y, Hayashi K, Ishigami M, Itoh A, Hirooka Y, Nakano I, Goto H.

Hepatogastroenterology. 2007 Apr-May;54(75):854-7.PMID: 17591078 [PubMed - indexed for MEDLINE]Related articles

Genetic variability of hepatitis C virus in chronically infected patients with viral breakthrough during interferon-ribavirin therapy.

Vuillermoz I, Khattab E, Sablon E, Ottevaere I, Durantel D, Vieux C, Trepo C, Zoulim F.

J Med Virol. 2004 Sep;74(1):41-53.PMID: 15258967 [PubMed - indexed for MEDLINE]Related articles

Lack of clinical significance of variability in the internal ribosome entry site of hepatitis C virus.

Thelu MA, Drouet E, Hilleret MN, Zarski JP.

J Med Virol. 2004 Mar;72(3):396-405.PMID: 14748063 [PubMed - indexed for MEDLINE]Related articles

Genetic distance and heterogenecity between quasispecies is a critical predictor to IFN response in Egyptian patients with HCV genotype-4.

Zekri AR, El-Din HM, Bahnassy AA, Khaled MM, Omar A, Fouad I, El-Hefnewi M, Thakeb F, El-Awady M.

Virol J. 2007 Feb 14;4:16.PMID: 17300723 [PubMed - indexed for MEDLINE]Related articlesFree article

Nucleotide sequence variations in the internal ribosome entry site of hepatitis C virus-1b: no association with efficacy of interferon therapy or serum HCV-RNA levels.

Yamamoto C, Enomoto N, Kurosaki M, Yu SH, Tazawa J, Izumi N, Marumo F, Sato C.

Hepatology. 1997 Dec;26(6):1616-20.PMID: 9398006 [PubMed - indexed for MEDLINE]Related articles

Virological response in patients with hepatitis C virus genotype 1b and a high viral load: impact of peginterferon-alpha-2a plus ribavirin dose reductions and host-related factors.

Yamada G, Iino S, Okuno T, Omata M, Kiyosawa K, Kumada H, Hayashi N, Sakai T.

Clin Drug Investig. 2008;28(1):9-16. Erratum in: Clin Drug Investig. 2008;28(4):210. PMID: 18081356 [PubMed - indexed for MEDLINE]Related articles

A mutational shift from domain III to II in the internal ribosome entry site of hepatitis C virus after interferon-ribavirin therapy.

Ogata K, Kashiwagi T, Iwahashi J, Hara K, Honda H, Ide T, Kumashiro R, Kohara M, Sata M, Watanabe H, Hamada N.

Arch Virol. 2008;153(8):1575-9. Epub 2008 Jul 1.PMID: 18592133 [PubMed - indexed for MEDLINE]Related articles

Virological effects of ISIS 14803, an antisense oligonucleotide inhibitor of hepatitis C virus (HCV) internal ribosome entry site (IRES), on HCV IRES in chronic hepatitis C patients and examination of the potential role of primary and secondary HCV resistance in the outcome of treatment.

Soler M, McHutchison JG, Kwoh TJ, Dorr FA, Pawlotsky JM.

Antivir Ther. 2004 Dec;9(6):953-68.PMID: 15651754 [PubMed - indexed for MEDLINE]Related articles

Mutations in the NS5A and E2-PePHD region of hepatitis C virus type 1b and correlation with the response to combination therapy with interferon and ribavirin.

Hung CH, Lee CM, Lu SN, Lee JF, Wang JH, Tung HD, Chen TM, Hu TH, Chen WJ, Changchien CS.

J Viral Hepat. 2003 Mar;10(2):87-94.PMID: 12614464 [PubMed - indexed for MEDLINE]Related articles

Secondary structure of the hepatitis C virus 5' untranslated region and efficacy of interferon therapy for chronic hepatitis C.

Suzuki K, Shinzawa H, Kuboki M, Ishibashi M, Yoshii E, Saito T, Takahashi T.

Liver. 1998 Oct;18(5):331-6.PMID: 9831362 [PubMed - indexed for MEDLINE]Related articles

Alterations to both the primary and predicted secondary structure of stem-loop IIIc of the hepatitis C virus 1b 5' untranslated region (5'UTR) lead to mutants severely defective in translation which cannot be complemented in trans by the wild-type 5'UTR sequence.

Tang S, Collier AJ, Elliott RM.

J Virol. 1999 Mar;73(3):2359-64.PMID: 9971819 [PubMed - indexed for MEDLINE]Related articlesFree article

Improved correlation between multiple mutations within the NS5A region and virological response in European patients chronically infected with hepatitis C virus type 1b undergoing combination therapy.

Sarrazin C, Berg T, Lee JH, Teuber G, Dietrich CF, Roth WK, Zeuzem S.

J Hepatol. 1999 Jun;30(6):1004-13.PMID: 10406177 [PubMed - indexed for MEDLINE]Related articles

Long term histological improvement and clearance of intrahepatic hepatitis C virus RNA following sustained response to interferon-ribavirin combination therapy in liver transplanted patients with hepatitis C virus recurrence.

Bizollon T, Ahmed SN, Radenne S, Chevallier M, Chevallier P, Parvaz P, Guichard S, Ducerf C, Baulieux J, Zoulim F, Trepo C.

Gut. 2003 Feb;52(2):283-7.PMID: 12524414 [PubMed - indexed for MEDLINE]Related articlesFree article

Hypervariable region 1 of hepatitis C virus genome and response to interferon therapy.

Grahovac B, Bingulac-Popović J, Vucelić B, Hrstić I, Ostojić R, Drazić V, Balija M, Grgicević D.

Clin Chem Lab Med. 2000 Sep;38(9):905-10.PMID: 11097348 [PubMed - indexed for MEDLINE]Related articles

Mutations in E2-PePHD, NS5A-PKRBD, NS5A-ISDR, and NS5A-V3 of hepatitis C virus genotype 1 and their relationships to pegylated interferon-ribavirin treatment responses.

Muñoz de Rueda P, Casado J, Patón R, Quintero D, Palacios A, Gila A, Quiles R, León J, Ruiz-Extremera A, Salmerón J.

J Virol. 2008 Jul;82(13):6644-53. Epub 2008 Apr 30.PMID: 18448540 [PubMed - indexed for MEDLINE]Related articlesFree article

Does sequencing the PKRBD of hepatitis C virus NS5A predict therapeutic response to combination therapy in an Australian population?

Macquillan GC, Niu X, Speers D, English S, Garas G, Harnett GB, Reed WD, Allan JE, Jeffrey GP.

J Gastroenterol Hepatol. 2004 May;19(5):551-7.PMID: 15086599 [PubMed - indexed for MEDLINE]Related articles

Correlation between translation efficiency and outcome of combination therapy in chronic hepatitis C genotype 3.

Yasmeen A, Hamid S, Granath FN, Lindström H, Elliott RM, Siddiqui AA, Persson MA.

J Viral Hepat. 2006 Feb;13(2):87-95.PMID: 16436126 [PubMed - indexed for MEDLINE]Related articles

Mutations in the interferon sensitivity-determining region (nonstructural 5A amino acid 2209-2248) in patients with hepatitis C-1b infection and correlating response to combined therapy of pegylated interferon and ribavirin.

Yen YH, Hung CH, Hu TH, Chen CH, Wu CM, Wang JH, Lu SN, Lee CM.

Aliment Pharmacol Ther. 2008 Jan 1;27(1):72-9. Epub 2007 Oct 25.PMID: 17973647 [PubMed - indexed for MEDLINE]Related articlesFree article