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    Results: 1 to 20 of 153

    1.

    Integrated analysis of breast cancer cell lines reveals unique signaling pathways.

    Heiser LM, Wang NJ, Talcott CL, Laderoute KR, Knapp M, Guan Y, Hu Z, Ziyad S, Weber BL, Laquerre S, Jackson JR, Wooster RF, Kuo WL, Gray JW, Spellman PT.

    Genome Biol. 2009;10(3):R31. Epub 2009 Mar 25.

    PMID:
    19317917
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    2.

    Basal subtype and MAPK/ERK kinase (MEK)-phosphoinositide 3-kinase feedback signaling determine susceptibility of breast cancer cells to MEK inhibition.

    Mirzoeva OK, Das D, Heiser LM, Bhattacharya S, Siwak D, Gendelman R, Bayani N, Wang NJ, Neve RM, Guan Y, Hu Z, Knight Z, Feiler HS, Gascard P, Parvin B, Spellman PT, Shokat KM, Wyrobek AJ, Bissell MJ, McCormick F, Kuo WL, Mills GB, Gray JW, Korn WM.

    Cancer Res. 2009 Jan 15;69(2):565-72.

    PMID:
    19147570
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    3.

    In vivo antitumor activity of MEK and phosphatidylinositol 3-kinase inhibitors in basal-like breast cancer models.

    Hoeflich KP, O'Brien C, Boyd Z, Cavet G, Guerrero S, Jung K, Januario T, Savage H, Punnoose E, Truong T, Zhou W, Berry L, Murray L, Amler L, Belvin M, Friedman LS, Lackner MR.

    Clin Cancer Res. 2009 Jul 15;15(14):4649-64. Epub 2009 Jun 30.

    PMID:
    19567590
    [PubMed - indexed for MEDLINE]
    Free Article
    4.

    Molecular profiling of breast cancer cell lines defines relevant tumor models and provides a resource for cancer gene discovery.

    Kao J, Salari K, Bocanegra M, Choi YL, Girard L, Gandhi J, Kwei KA, Hernandez-Boussard T, Wang P, Gazdar AF, Minna JD, Pollack JR.

    PLoS One. 2009 Jul 3;4(7):e6146.

    PMID:
    19582160
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    5.

    Expression of the protein phosphatase 1 inhibitor KEPI is downregulated in breast cancer cell lines and tissues and involved in the regulation of the tumor suppressor EGR1 via the MEK-ERK pathway.

    Wenzel K, Daskalow K, Herse F, Seitz S, Zacharias U, Schenk JA, Schulz H, Hubner N, Micheel B, Schlag PM, Osterziel KJ, Ozcelik C, Scherneck S, Jandrig B.

    Biol Chem. 2007 May;388(5):489-95.

    PMID:
    17516844
    [PubMed - indexed for MEDLINE]
    6.

    Proteomic analysis of breast cancer molecular subtypes and biomarkers of response to targeted kinase inhibitors using reverse-phase protein microarrays.

    Boyd ZS, Wu QJ, O'Brien C, Spoerke J, Savage H, Fielder PJ, Amler L, Yan Y, Lackner MR.

    Mol Cancer Ther. 2008 Dec;7(12):3695-706. Epub 2008 Dec 3.

    PMID:
    19056674
    [PubMed - indexed for MEDLINE]
    Free Article
    7.

    Dasatinib, an orally active small molecule inhibitor of both the src and abl kinases, selectively inhibits growth of basal-type/"triple-negative" breast cancer cell lines growing in vitro.

    Finn RS, Dering J, Ginther C, Wilson CA, Glaspy P, Tchekmedyian N, Slamon DJ.

    Breast Cancer Res Treat. 2007 Nov;105(3):319-26. Epub 2007 Feb 1.

    PMID:
    17268817
    [PubMed - indexed for MEDLINE]
    8.

    Metformin induces unique biological and molecular responses in triple negative breast cancer cells.

    Liu B, Fan Z, Edgerton SM, Deng XS, Alimova IN, Lind SE, Thor AD.

    Cell Cycle. 2009 Jul 1;8(13):2031-40. Epub 2009 Jul 21.

    PMID:
    19440038
    [PubMed - indexed for MEDLINE]
    Free Article
    9.

    EGFR associated expression profiles vary with breast tumor subtype.

    Hoadley KA, Weigman VJ, Fan C, Sawyer LR, He X, Troester MA, Sartor CI, Rieger-House T, Bernard PS, Carey LA, Perou CM.

    BMC Genomics. 2007 Jul 31;8:258.

    PMID:
    17663798
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    11.

    Intracellular signaling pathways regulate hormone-dependent kallikrein gene expression.

    Paliouras M, Diamandis EP.

    Tumour Biol. 2008;29(2):63-75. Epub 2008 Jun 2.

    PMID:
    18515984
    [PubMed - indexed for MEDLINE]
    12.

    Regulation of macrophage inhibitory factor (MIF) by epidermal growth factor receptor (EGFR) in the MCF10AT model of breast cancer progression.

    Lim S, Choong LY, Kuan CP, Yunhao C, Lim YP.

    J Proteome Res. 2009 Aug;8(8):4062-76.

    PMID:
    19530702
    [PubMed - indexed for MEDLINE]
    13.

    Cytokeratin 19 regulates endoplasmic reticulum stress and inhibits ERp29 expression via p38 MAPK/XBP-1 signaling in breast cancer cells.

    Bambang IF, Lu D, Li H, Chiu LL, Lau QC, Koay E, Zhang D.

    Exp Cell Res. 2009 Jul 1;315(11):1964-74. Epub 2009 Mar 2.

    PMID:
    19265690
    [PubMed - indexed for MEDLINE]
    14.

    Analysis of signaling pathways in 90 cancer cell lines by protein lysate array.

    Mendes KN, Nicorici D, Cogdell D, Tabus I, Yli-Harja O, Guerra R, Hamilton SR, Zhang W.

    J Proteome Res. 2007 Jul;6(7):2753-67. Epub 2007 Jun 12.

    PMID:
    17564428
    [PubMed - indexed for MEDLINE]
    15.

    Phosphorylation of the ErbB3 binding protein Ebp1 by p21-activated kinase 1 in breast cancer cells.

    Akinmade D, Talukder AH, Zhang Y, Luo WM, Kumar R, Hamburger AW.

    Br J Cancer. 2008 Mar 25;98(6):1132-40. Epub 2008 Feb 19.

    PMID:
    18283314
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    16.

    Stromal cell-derived factor-1/CXCR4 enhanced motility of human osteosarcoma cells involves MEK1/2, ERK and NF-kappaB-dependent pathways.

    Huang CY, Lee CY, Chen MY, Yang WH, Chen YH, Chang CH, Hsu HC, Fong YC, Tang CH.

    J Cell Physiol. 2009 Oct;221(1):204-12.

    PMID:
    19496172
    [PubMed - indexed for MEDLINE]
    17.

    Integrating signals between cAMP and MAPK pathways in breast cancer.

    Castoria G, Migliaccio A, D'Amato L, Di Stasio R, Ciociola A, Lombardi M, Bilancio A, Di Domenico M, de Falco A, Auricchio F.

    Front Biosci. 2008 Jan 1;13:1318-27. Review.

    PMID:
    17981632
    [PubMed - indexed for MEDLINE]
    18.

    Targeting p21-activated kinase 1 (PAK1) to induce apoptosis of tumor cells.

    Ong CC, Jubb AM, Haverty PM, Zhou W, Tran V, Truong T, Turley H, O'Brien T, Vucic D, Harris AL, Belvin M, Friedman LS, Blackwood EM, Koeppen H, Hoeflich KP.

    Proc Natl Acad Sci U S A. 2011 Apr 26;108(17):7177-82. Epub 2011 Apr 11.

    PMID:
    21482786
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    19.

    Characterization of a novel mitogen-activated protein kinase kinase 1/2 inhibitor with a unique mechanism of action for cancer therapy.

    Daouti S, Wang H, Li WH, Higgins B, Kolinsky K, Packman K, Specian A Jr, Kong N, Huby N, Wen Y, Xiang Q, Podlaski FJ, He Y, Fotouhi N, Heimbrook D, Niu H.

    Cancer Res. 2009 Mar 1;69(5):1924-32. Epub 2009 Feb 24.

    PMID:
    19244124
    [PubMed - indexed for MEDLINE]
    Free Article
    20.

    Mitogen-activated protein kinase phosphatase-1 in human breast cancer independently predicts prognosis and is repressed by doxorubicin.

    Rojo F, González-Navarrete I, Bragado R, Dalmases A, Menéndez S, Cortes-Sempere M, Suárez C, Oliva C, Servitja S, Rodriguez-Fanjul V, Sánchez-Pérez I, Campas C, Corominas JM, Tusquets I, Bellosillo B, Serrano S, Perona R, Rovira A, Albanell J.

    Clin Cancer Res. 2009 May 15;15(10):3530-9. Epub 2009 May 5.

    PMID:
    19417026
    [PubMed - indexed for MEDLINE]
    Free Article

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