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Particles induce apical plasma membrane enlargement in epithelial lung cell line depending on particle surface area dose.

Brandenberger C, Rothen-Rutishauser B, Blank F, Gehr P, Mühlfeld C.

Respir Res. 2009 Mar 12;10:22.PMID: 19284624 [PubMed - indexed for MEDLINE]Related articlesFree article

Endocytosis, oxidative stress and IL-8 expression in human lung epithelial cells upon treatment with fine and ultrafine TiO2: role of the specific surface area and of surface methylation of the particles.

Singh S, Shi T, Duffin R, Albrecht C, van Berlo D, Höhr D, Fubini B, Martra G, Fenoglio I, Borm PJ, Schins RP.

Toxicol Appl Pharmacol. 2007 Jul 15;222(2):141-51. Epub 2007 May 18.PMID: 17599375 [PubMed - indexed for MEDLINE]Related articles

Size-dependent proinflammatory effects of ultrafine polystyrene particles: a role for surface area and oxidative stress in the enhanced activity of ultrafines.

Brown DM, Wilson MR, MacNee W, Stone V, Donaldson K.

Toxicol Appl Pharmacol. 2001 Sep 15;175(3):191-9.PMID: 11559017 [PubMed - indexed for MEDLINE]Related articles

Winter fine particulate matter from Milan induces morphological and functional alterations in human pulmonary epithelial cells (A549).

Gualtieri M, Mantecca P, Corvaja V, Longhin E, Perrone MG, Bolzacchini E, Camatini M.

Toxicol Lett. 2009 Jul 10;188(1):52-62. Epub 2009 Mar 20.PMID: 19433270 [PubMed - indexed for MEDLINE]Related articles

The pro-inflammatory effects of low-toxicity low-solubility particles, nanoparticles and fine particles, on epithelial cells in vitro: the role of surface area.

Monteiller C, Tran L, MacNee W, Faux S, Jones A, Miller B, Donaldson K.

Occup Environ Med. 2007 Sep;64(9):609-15. Epub 2007 Apr 4.PMID: 17409182 [PubMed - indexed for MEDLINE]Related articles

Assessing toxicity of fine and nanoparticles: comparing in vitro measurements to in vivo pulmonary toxicity profiles.

Sayes CM, Reed KL, Warheit DB.

Toxicol Sci. 2007 May;97(1):163-80. Epub 2007 Feb 14.PMID: 17301066 [PubMed - indexed for MEDLINE]Related articlesFree article

Significance of particle parameters in the evaluation of exposure-dose-response relationships of inhaled particles.

Oberdorster G.

Inhal Toxicol. 1996;8 Suppl:73-89. Review.PMID: 11542496 [PubMed - indexed for MEDLINE]Related articles

Combustion-derived ultrafine particles transport organic toxicants to target respiratory cells.

Penn A, Murphy G, Barker S, Henk W, Penn L.

Environ Health Perspect. 2005 Aug;113(8):956-63.PMID: 16079063 [PubMed - indexed for MEDLINE]Related articlesFree article

Fine environmental particulate engenders alterations in human lung epithelial A549 cells.

Calcabrini A, Meschini S, Marra M, Falzano L, Colone M, De Berardis B, Paoletti L, Arancia G, Fiorentini C.

Environ Res. 2004 May;95(1):82-91.PMID: 15068934 [PubMed - indexed for MEDLINE]Related articles

An optimized in vitro model of the respiratory tract wall to study particle cell interactions.

Blank F, Rothen-Rutishauser BM, Schurch S, Gehr P.

J Aerosol Med. 2006 Fall;19(3):392-405.PMID: 17034314 [PubMed - indexed for MEDLINE]Related articles

Dose-controlled exposure of A549 epithelial cells at the air-liquid interface to airborne ultrafine carbonaceous particles.

Bitterle E, Karg E, Schroeppel A, Kreyling WG, Tippe A, Ferron GA, Schmid O, Heyder J, Maier KL, Hofer T.

Chemosphere. 2006 Dec;65(10):1784-90. Epub 2006 Jun 9.PMID: 16762398 [PubMed - indexed for MEDLINE]Related articles

Changes in F-actin organization induced by hard metal particle exposure in rat pulmonary epithelial cells using laser scanning confocal microscopy.

Antonini JM, Starks K, Roberts JR, Millecchia L, Yang HM, Rao KM.

In Vitr Mol Toxicol. 2000 Spring;13(1):5-16.PMID: 10900403 [PubMed - indexed for MEDLINE]Related articles

Particle-induced cytokine responses in cardiac cell cultures--the effect of particles versus soluble mediators released by particle-exposed lung cells.

Totlandsdal AI, Refsnes M, Skomedal T, Osnes JB, Schwarze PE, Låg M.

Toxicol Sci. 2008 Nov;106(1):233-41. Epub 2008 Aug 11.PMID: 18700232 [PubMed - indexed for MEDLINE]Related articlesFree article

Ultrafine particles cross cellular membranes by nonphagocytic mechanisms in lungs and in cultured cells.

Geiser M, Rothen-Rutishauser B, Kapp N, Schürch S, Kreyling W, Schulz H, Semmler M, Im Hof V, Heyder J, Gehr P.

Environ Health Perspect. 2005 Nov;113(11):1555-60.PMID: 16263511 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of polystyrene particle density on type II pneumocytes.

Gassion C, Walsh-Guedon S, Tucci M, Hamadain E, Benghuzzi H.

Biomed Sci Instrum. 2006;42:181-6.PMID: 16817605 [PubMed - indexed for MEDLINE]Related articles

Importance of size and composition of particles for effects on cells in vitro.

Schwarze PE, Øvrevik J, Hetland RB, Becher R, Cassee FR, Låg M, Løvik M, Dybing E, Refsnes M.

Inhal Toxicol. 2007;19 Suppl 1:17-22. Review.PMID: 17886045 [PubMed - indexed for MEDLINE]Related articles

Evaluation of cytotoxic concentration-time response in A549 cells exposed to respirable alpha-quartz.

Fanizza C, Fresegna AM, Maiello R, Paba E, Cavallo D.

J Appl Toxicol. 2009 Aug;29(6):537-44.PMID: 19444853 [PubMed - indexed for MEDLINE]Related articles

Pulmonary bioassay studies with nanoscale and fine-quartz particles in rats: toxicity is not dependent upon particle size but on surface characteristics.

Warheit DB, Webb TR, Colvin VL, Reed KL, Sayes CM.

Toxicol Sci. 2007 Jan;95(1):270-80. Epub 2006 Oct 9.PMID: 17030555 [PubMed - indexed for MEDLINE]Related articlesFree article

Proinflammatory effect of fine and ultrafine particulate matter using size-resolved urban aerosols from Paris.

Ramgolam K, Chevaillier S, Marano F, Baeza-Squiban A, Martinon L.

Chemosphere. 2008 Jul;72(9):1340-6. Epub 2008 Jun 13.PMID: 18555515 [PubMed - indexed for MEDLINE]Related articles

Internalization of carcinogenic lead chromate particles by cultured normal human lung epithelial cells: formation of intracellular lead-inclusion bodies and induction of apoptosis.

Singh J, Pritchard DE, Carlisle DL, Mclean JA, Montaser A, Orenstein JM, Patierno SR.

Toxicol Appl Pharmacol. 1999 Dec 15;161(3):240-8.PMID: 10620481 [PubMed - indexed for MEDLINE]Related articles