PubMed

Short-term exercise training does not stimulate skeletal muscle ATP synthesis in relatives of humans with type 2 diabetes.

Kacerovsky-Bielesz G, Chmelik M, Ling C, Pokan R, Szendroedi J, Farukuoye M, Kacerovsky M, Schmid AI, Gruber S, Wolzt M, Moser E, Pacini G, Smekal G, Groop L, Roden M.

Diabetes. 2009 Jun;58(6):1333-41. Epub 2009 Mar 5.PMID: 19265027 [PubMed - indexed for MEDLINE]Related articlesFree article

Impact of exercise training on insulin sensitivity, physical fitness, and muscle oxidative capacity in first-degree relatives of type 2 diabetic patients.

Østergård T, Andersen JL, Nyholm B, Lund S, Nair KS, Saltin B, Schmitz O.

Am J Physiol Endocrinol Metab. 2006 May;290(5):E998-1005. Epub 2005 Dec 13.PMID: 16352678 [PubMed - indexed for MEDLINE]Related articlesFree article

Decreased insulin-stimulated ATP synthesis and phosphate transport in muscle of insulin-resistant offspring of type 2 diabetic parents.

Petersen KF, Dufour S, Shulman GI.

PLoS Med. 2005 Sep;2(9):e233. Epub 2005 Aug 16.PMID: 16089501 [PubMed - indexed for MEDLINE]Related articlesFree article

Exercise training increases glycogen synthase activity and GLUT4 expression but not insulin signaling in overweight nondiabetic and type 2 diabetic subjects.

Christ-Roberts CY, Pratipanawatr T, Pratipanawatr W, Berria R, Belfort R, Kashyap S, Mandarino LJ.

Metabolism. 2004 Sep;53(9):1233-42.PMID: 15334390 [PubMed - indexed for MEDLINE]Related articles

Muscle mitochondrial ATP synthesis and glucose transport/phosphorylation in type 2 diabetes.

Szendroedi J, Schmid AI, Chmelik M, Toth C, Brehm A, Krssak M, Nowotny P, Wolzt M, Waldhausl W, Roden M.

PLoS Med. 2007 May;4(5):e154.PMID: 17472434 [PubMed - indexed for MEDLINE]Related articlesFree article

Genetic and epigenetic factors are associated with expression of respiratory chain component NDUFB6 in human skeletal muscle.

Ling C, Poulsen P, Simonsson S, Rönn T, Holmkvist J, Almgren P, Hagert P, Nilsson E, Mabey AG, Nilsson P, Vaag A, Groop L.

J Clin Invest. 2007 Nov;117(11):3427-35.PMID: 17948130 [PubMed - indexed for MEDLINE]Related articlesFree article

Influence of the PPAR-gamma2 Pro12Ala and ACE I/D polymorphisms on insulin sensitivity and training effects in healthy offspring of type 2 diabetic subjects.

Østergård T, Ek J, Hamid Y, Saltin B, Pedersen OB, Hansen T, Schmitz O.

Horm Metab Res. 2005 Feb;37(2):99-105.PMID: 15778927 [PubMed - indexed for MEDLINE]Related articles

Genes involved in mitochondrial biogenesis/function are induced in response to bilio-pancreatic diversion in morbidly obese individuals with normal glucose tolerance but not in type 2 diabetic patients.

Hernández-Alvarez MI, Chiellini C, Manco M, Naon D, Liesa M, Palacín M, Mingrone G, Zorzano A.

Diabetologia. 2009 Aug;52(8):1618-27. Epub 2009 Jun 6.PMID: 19504086 [PubMed - indexed for MEDLINE]Related articles

Epigenetic regulation of PPARGC1A in human type 2 diabetic islets and effect on insulin secretion.

Ling C, Del Guerra S, Lupi R, Rönn T, Granhall C, Luthman H, Masiello P, Marchetti P, Groop L, Del Prato S.

Diabetologia. 2008 Apr;51(4):615-22. Epub 2008 Feb 13.PMID: 18270681 [PubMed - indexed for MEDLINE]Related articlesFree article

Disassociation of muscle triglyceride content and insulin sensitivity after exercise training in patients with Type 2 diabetes.

Bruce CR, Kriketos AD, Cooney GJ, Hawley JA.

Diabetologia. 2004 Jan;47(1):23-30. Epub 2003 Dec 12.PMID: 14673522 [PubMed - indexed for MEDLINE]Related articles

Genetic variations in PPARD and PPARGC1A determine mitochondrial function and change in aerobic physical fitness and insulin sensitivity during lifestyle intervention.

Stefan N, Thamer C, Staiger H, Machicao F, Machann J, Schick F, Venter C, Niess A, Laakso M, Fritsche A, Häring HU.

J Clin Endocrinol Metab. 2007 May;92(5):1827-33. Epub 2007 Feb 27.PMID: 17327385 [PubMed - indexed for MEDLINE]Related articlesFree article

Increased glucose transport-phosphorylation and muscle glycogen synthesis after exercise training in insulin-resistant subjects.

Perseghin G, Price TB, Petersen KF, Roden M, Cline GW, Gerow K, Rothman DL, Shulman GI.

N Engl J Med. 1996 Oct 31;335(18):1357-62.PMID: 8857019 [PubMed - indexed for MEDLINE]Related articlesFree article

Reduced skeletal muscle oxygen uptake and reduced beta-cell function: two early abnormalities in normal glucose-tolerant offspring of patients with type 2 diabetes.

Thamer C, Stumvoll M, Niess A, Tschritter O, Haap M, Becker R, Shirkavand F, Bachmann O, Rett K, Volk A, Häring H, Fritsche A.

Diabetes Care. 2003 Jul;26(7):2126-32.PMID: 12832324 [PubMed - indexed for MEDLINE]Related articlesFree article

Effect of insulin on human skeletal muscle mitochondrial ATP production, protein synthesis, and mRNA transcripts.

Stump CS, Short KR, Bigelow ML, Schimke JM, Nair KS.

Proc Natl Acad Sci U S A. 2003 Jun 24;100(13):7996-8001. Epub 2003 Jun 13.PMID: 12808136 [PubMed - indexed for MEDLINE]Related articlesFree article

Impact of aerobic exercise training on age-related changes in insulin sensitivity and muscle oxidative capacity.

Short KR, Vittone JL, Bigelow ML, Proctor DN, Rizza RA, Coenen-Schimke JM, Nair KS.

Diabetes. 2003 Aug;52(8):1888-96.PMID: 12882902 [PubMed - indexed for MEDLINE]Related articlesFree article

Skeletal muscle neuronal nitric oxide synthase micro protein is reduced in people with impaired glucose homeostasis and is not normalized by exercise training.

Bradley SJ, Kingwell BA, Canny BJ, McConell GK.

Metabolism. 2007 Oct;56(10):1405-11.PMID: 17884453 [PubMed - indexed for MEDLINE]Related articles

Intracellular skeletal muscle glucose metabolism is differentially altered by dexamethasone treatment of normoglycemic relatives of type 2 diabetic patients.

Henriksen JE, Alford F, Vaag A, Handberg A, Beck-Nielsen H.

Metabolism. 1999 Sep;48(9):1128-35.PMID: 10484052 [PubMed - indexed for MEDLINE]Related articles

Reduced basal ATP synthetic flux of skeletal muscle in patients with previous acromegaly.

Szendroedi J, Zwettler E, Schmid AI, Chmelik M, Pacini G, Kacerovsky G, Smekal G, Nowotny P, Wagner O, Schnack C, Schernthaner G, Klaushofer K, Roden M.

PLoS One. 2008;3(12):e3958. Epub 2008 Dec 18.PMID: 19093000 [PubMed - indexed for MEDLINE]Related articlesFree article

Effect of supervised progressive resistance-exercise training protocol on insulin sensitivity, glycemia, lipids, and body composition in Asian Indians with type 2 diabetes.

Misra A, Alappan NK, Vikram NK, Goel K, Gupta N, Mittal K, Bhatt S, Luthra K.

Diabetes Care. 2008 Jul;31(7):1282-7. Epub 2008 Mar 3.PMID: 18316394 [PubMed - indexed for MEDLINE]Related articlesFree article

Short-term aerobic exercise training in obese humans with type 2 diabetes mellitus improves whole-body insulin sensitivity through gains in peripheral, not hepatic insulin sensitivity.

Winnick JJ, Sherman WM, Habash DL, Stout MB, Failla ML, Belury MA, Schuster DP.

J Clin Endocrinol Metab. 2008 Mar;93(3):771-8. Epub 2007 Dec 11.PMID: 18073312 [PubMed - indexed for MEDLINE]Related articlesFree article