PubMed

Adaptive beta-cell proliferation is severely restricted with advanced age.

Rankin MM, Kushner JA.

Diabetes. 2009 Jun;58(6):1365-72. Epub 2009 Mar 5.PMID: 19265026 [PubMed - indexed for MEDLINE]Related articlesFree article

Age-dependent decline in beta-cell proliferation restricts the capacity of beta-cell regeneration in mice.

Tschen SI, Dhawan S, Gurlo T, Bhushan A.

Diabetes. 2009 Jun;58(6):1312-20. Epub 2009 Feb 19.PMID: 19228811 [PubMed - indexed for MEDLINE]Related articlesFree article

Beta-cell proliferation, but not neogenesis, following 60% partial pancreatectomy is impaired in the absence of FoxM1.

Ackermann Misfeldt A, Costa RH, Gannon M.

Diabetes. 2008 Nov;57(11):3069-77. Epub 2008 Aug 26.PMID: 18728229 [PubMed - indexed for MEDLINE]Related articlesFree article

Partial pancreatectomy in adult humans does not provoke beta-cell regeneration.

Menge BA, Tannapfel A, Belyaev O, Drescher R, Müller C, Uhl W, Schmidt WE, Meier JJ.

Diabetes. 2008 Jan;57(1):142-9. Epub 2007 Oct 24.PMID: 17959931 [PubMed - indexed for MEDLINE]Related articlesFree article

Exendin-4 stimulates both beta-cell replication and neogenesis, resulting in increased beta-cell mass and improved glucose tolerance in diabetic rats.

Xu G, Stoffers DA, Habener JF, Bonner-Weir S.

Diabetes. 1999 Dec;48(12):2270-6.PMID: 10580413 [PubMed - indexed for MEDLINE]Related articlesFree article

Long-term caloric restriction delays age-related decline in proliferation capacity of murine lens epithelial cells in vitro and in vivo.

Li Y, Yan Q, Wolf NS.

Invest Ophthalmol Vis Sci. 1997 Jan;38(1):100-7.PMID: 9008635 [PubMed - indexed for MEDLINE]Related articlesFree article

Continuous stimulation of human glucagon-like peptide-1 (7-36) amide in a mouse model (NOD) delays onset of autoimmune type 1 diabetes.

Zhang J, Tokui Y, Yamagata K, Kozawa J, Sayama K, Iwahashi H, Okita K, Miuchi M, Konya H, Hamaguchi T, Namba M, Shimomura I, Miyagawa JI.

Diabetologia. 2007 Sep;50(9):1900-9. Epub 2007 Jul 14.PMID: 17632702 [PubMed - indexed for MEDLINE]Related articles

Increasing GLP-1-induced beta-cell proliferation by silencing the negative regulators of signaling cAMP response element modulator-alpha and DUSP14.

Klinger S, Poussin C, Debril MB, Dolci W, Halban PA, Thorens B.

Diabetes. 2008 Mar;57(3):584-93. Epub 2007 Nov 19.PMID: 18025410 [PubMed - indexed for MEDLINE]Related articlesFree article

Regulation of pancreatic beta-cell regeneration in the normoglycemic 60% partial-pancreatectomy mouse.

Peshavaria M, Larmie BL, Lausier J, Satish B, Habibovic A, Roskens V, Larock K, Everill B, Leahy JL, Jetton TL.

Diabetes. 2006 Dec;55(12):3289-98.PMID: 17130472 [PubMed - indexed for MEDLINE]Related articlesFree article

Role of endogenous glucagon-like peptide-1 in islet regeneration after partial pancreatectomy.

De León DD, Deng S, Madani R, Ahima RS, Drucker DJ, Stoffers DA.

Diabetes. 2003 Feb;52(2):365-71.PMID: 12540609 [PubMed - indexed for MEDLINE]Related articlesFree article

Glucagon-like peptide-1 and exendin-4 stimulate beta-cell neogenesis in streptozotocin-treated newborn rats resulting in persistently improved glucose homeostasis at adult age.

Tourrel C, Bailbé D, Meile MJ, Kergoat M, Portha B.

Diabetes. 2001 Jul;50(7):1562-70.PMID: 11423477 [PubMed - indexed for MEDLINE]Related articlesFree article

Glucagon-like peptide-1.

Doyle ME, Egan JM.

Recent Prog Horm Res. 2001;56:377-99. Review.PMID: 11237222 [PubMed - indexed for MEDLINE]Related articlesFree article

Undernutrition does not alter the activation of beta-cell neogenesis and replication in adult rats after partial pancreatectomy.

Fernández E, Martín MA, Fajardo S, Bailbé D, Gangnerau MN, Portha B, Escrivá F, Serradas P, Alvarez C.

Am J Physiol Endocrinol Metab. 2006 Nov;291(5):E913-21. Epub 2006 Jun 6.PMID: 16757552 [PubMed - indexed for MEDLINE]Related articlesFree article

Impaired pancreatic duct-cell growth in focal areas of regeneration after partial pancreatectomy in the adult Goto-Kakizaki rat, a spontaneous model of non-insulin dependent diabetes mellitus.

Plachot C, Portha B.

Histochem J. 2001 Mar;33(3):141-7.PMID: 11508337 [PubMed - indexed for MEDLINE]Related articles

Ontogeny of regeneration of beta-cells in the neonatal rat after treatment with streptozotocin.

Thyssen S, Arany E, Hill DJ.

Endocrinology. 2006 May;147(5):2346-56. Epub 2006 Feb 16.PMID: 16484329 [PubMed - indexed for MEDLINE]Related articlesFree article

Regulation of pancreatic beta-cell mass and proliferation by SOCS-3.

Lindberg K, Rønn SG, Tornehave D, Richter H, Hansen JA, Rømer J, Jackerott M, Billestrup N.

J Mol Endocrinol. 2005 Oct;35(2):231-43.PMID: 16216905 [PubMed - indexed for MEDLINE]Related articlesFree article

Exendin-(9-39) corrects fasting hypoglycemia in SUR-1-/- mice by lowering cAMP in pancreatic beta-cells and inhibiting insulin secretion.

De León DD, Li C, Delson MI, Matschinsky FM, Stanley CA, Stoffers DA.

J Biol Chem. 2008 Sep 19;283(38):25786-93. Epub 2008 Jul 17.PMID: 18635551 [PubMed - indexed for MEDLINE]Related articlesFree article

Glucagon-like peptide-1 treatment delays the onset of diabetes in 8 week-old db/db mice.

Wang Q, Brubaker PL.

Diabetologia. 2002 Sep;45(9):1263-73. Epub 2002 Apr 26.PMID: 12242459 [PubMed - indexed for MEDLINE]Related articles

Impaired beta-cell regeneration after partial pancreatectomy in the adult Goto-Kakizaki rat, a spontaneous model of type II diabetes.

Plachot C, Movassat J, Portha B.

Histochem Cell Biol. 2001 Aug;116(2):131-9.PMID: 11685541 [PubMed - indexed for MEDLINE]Related articles

beta-cell failure in diabetes and preservation by clinical treatment.

Wajchenberg BL.

Endocr Rev. 2007 Apr;28(2):187-218. Epub 2007 Mar 12. Review.PMID: 17353295 [PubMed - indexed for MEDLINE]Related articlesFree article