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    Results: 1 to 20 of 149

    1.

    Genetic variation in KCNQ1 associates with fasting glucose and beta-cell function: a study of 3,734 subjects comprising three ethnicities living in Singapore.

    Tan JT, Nurbaya S, Gardner D, Ye S, Tai ES, Ng DP.

    Diabetes. 2009 Jun;58(6):1445-9. Epub 2009 Feb 27.PMID: 19252135 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    SNPs in KCNQ1 are associated with susceptibility to type 2 diabetes in East Asian and European populations.

    Unoki H, Takahashi A, Kawaguchi T, Hara K, Horikoshi M, Andersen G, Ng DP, Holmkvist J, Borch-Johnsen K, Jørgensen T, Sandbaek A, Lauritzen T, Hansen T, Nurbaya S, Tsunoda T, Kubo M, Babazono T, Hirose H, Hayashi M, Iwamoto Y, Kashiwagi A, Kaku K, Kawamori R, Tai ES, Pedersen O, Kamatani N, Kadowaki T, Kikkawa R, Nakamura Y, Maeda S.

    Nat Genet. 2008 Sep;40(9):1098-102.PMID: 18711366 [PubMed - indexed for MEDLINE]Related articles

    3.

    Variations in KCNQ1 are associated with type 2 diabetes and beta cell function in a Chinese population.

    Hu C, Wang C, Zhang R, Ma X, Wang J, Lu J, Qin W, Bao Y, Xiang K, Jia W.

    Diabetologia. 2009 Jul;52(7):1322-5. Epub 2009 Mar 24.PMID: 19308350 [PubMed - indexed for MEDLINE]Related articles

    4.

    Variants in KCNQ1 are associated with susceptibility to type 2 diabetes mellitus.

    Yasuda K, Miyake K, Horikawa Y, Hara K, Osawa H, Furuta H, Hirota Y, Mori H, Jonsson A, Sato Y, Yamagata K, Hinokio Y, Wang HY, Tanahashi T, Nakamura N, Oka Y, Iwasaki N, Iwamoto Y, Yamada Y, Seino Y, Maegawa H, Kashiwagi A, Takeda J, Maeda E, Shin HD, Cho YM, Park KS, Lee HK, Ng MC, Ma RC, So WY, Chan JC, Lyssenko V, Tuomi T, Nilsson P, Groop L, Kamatani N, Sekine A, Nakamura Y, Yamamoto K, Yoshida T, Tokunaga K, Itakura M, Makino H, Nanjo K, Kadowaki T, Kasuga M.

    Nat Genet. 2008 Sep;40(9):1092-7.PMID: 18711367 [PubMed - indexed for MEDLINE]Related articles

    5.

    Association of type 2 diabetes candidate polymorphisms in KCNQ1 with incretin and insulin secretion.

    Müssig K, Staiger H, Machicao F, Kirchhoff K, Guthoff M, Schäfer SA, Kantartzis K, Silbernagel G, Stefan N, Holst JJ, Gallwitz B, Häring HU, Fritsche A.

    Diabetes. 2009 Jul;58(7):1715-20. Epub 2009 Apr 14.PMID: 19366866 [PubMed - indexed for MEDLINE]Related articlesFree article

    6.

    The type 2 diabetes associated minor allele of rs2237895 KCNQ1 associates with reduced insulin release following an oral glucose load.

    Holmkvist J, Banasik K, Andersen G, Unoki H, Jensen TS, Pisinger C, Borch-Johnsen K, Sandbaek A, Lauritzen T, Brunak S, Maeda S, Hansen T, Pedersen O.

    PLoS One. 2009 Jun 11;4(6):e5872.PMID: 19516902 [PubMed - indexed for MEDLINE]Related articlesFree article

    7.

    Variants in KCNQ1 are associated with susceptibility to type 2 diabetes in the population of mainland China.

    Liu Y, Zhou DZ, Zhang D, Chen Z, Zhao T, Zhang Z, Ning M, Hu X, Yang YF, Zhang ZF, Yu L, He L, Xu H.

    Diabetologia. 2009 Jul;52(7):1315-21. Epub 2009 May 12.PMID: 19448982 [PubMed - indexed for MEDLINE]Related articlesFree article

    8.

    FTO variants are associated with obesity in the Chinese and Malay populations in Singapore.

    Tan JT, Dorajoo R, Seielstad M, Sim XL, Ong RT, Chia KS, Wong TY, Saw SM, Chew SK, Aung T, Tai ES.

    Diabetes. 2008 Oct;57(10):2851-7. Epub 2008 Jul 3.PMID: 18599522 [PubMed - indexed for MEDLINE]Related articlesFree article

    9.

    Polymorphisms within the novel type 2 diabetes risk locus MTNR1B determine beta-cell function.

    Staiger H, Machicao F, Schäfer SA, Kirchhoff K, Kantartzis K, Guthoff M, Silbernagel G, Stefan N, Häring HU, Fritsche A.

    PLoS One. 2008;3(12):e3962. Epub 2008 Dec 17.PMID: 19088850 [PubMed - indexed for MEDLINE]Related articlesFree article

    10.

    Polymorphisms Identified through Genome-Wide Association Studies and Their Associations with Type 2 Diabetes in Chinese, Malays, and Asian-Indians in Singapore.

    Tan JT, Ng DP, Nurbaya S, Ye S, Lim XL, Leong H, Seet LT, Siew WF, Kon W, Wong TY, Saw SM, Aung T, Chia KS, Lee J, Chew SK, Seielstad M, Tai ES.

    J Clin Endocrinol Metab. 2009 Nov 5. [Epub ahead of print]PMID: 19892838 [PubMed - as supplied by publisher]Related articles

    11.

    G-allele of intronic rs10830963 in MTNR1B confers increased risk of impaired fasting glycemia and type 2 diabetes through an impaired glucose-stimulated insulin release: studies involving 19,605 Europeans.

    Sparsø T, Bonnefond A, Andersson E, Bouatia-Naji N, Holmkvist J, Wegner L, Grarup N, Gjesing AP, Banasik K, Cavalcanti-Proença C, Marchand M, Vaxillaire M, Charpentier G, Jarvelin MR, Tichet J, Balkau B, Marre M, Lévy-Marchal C, Faerch K, Borch-Johnsen K, Jørgensen T, Madsbad S, Poulsen P, Vaag A, Dina C, Hansen T, Pedersen O, Froguel P.

    Diabetes. 2009 Jun;58(6):1450-6. Epub 2009 Mar 26.PMID: 19324940 [PubMed - indexed for MEDLINE]Related articlesFree article

    12.

    Confirmation of multiple risk Loci and genetic impacts by a genome-wide association study of type 2 diabetes in the Japanese population.

    Takeuchi F, Serizawa M, Yamamoto K, Fujisawa T, Nakashima E, Ohnaka K, Ikegami H, Sugiyama T, Katsuya T, Miyagishi M, Nakashima N, Nawata H, Nakamura J, Kono S, Takayanagi R, Kato N.

    Diabetes. 2009 Jul;58(7):1690-9. Epub 2009 Apr 28.PMID: 19401414 [PubMed - indexed for MEDLINE]Related articlesFree article

    13.

    A variant in the KCNQ1 gene predicts future type 2 diabetes and mediates impaired insulin secretion.

    Jonsson A, Isomaa B, Tuomi T, Taneera J, Salehi A, Nilsson P, Groop L, Lyssenko V.

    Diabetes. 2009 Oct;58(10):2409-13. Epub 2009 Jul 7.PMID: 19584308 [PubMed - indexed for MEDLINE]Related articles

    14.

    Impact of nine common type 2 diabetes risk polymorphisms in Asian Indian Sikhs: PPARG2 (Pro12Ala), IGF2BP2, TCF7L2 and FTO variants confer a significant risk.

    Sanghera DK, Ortega L, Han S, Singh J, Ralhan SK, Wander GS, Mehra NK, Mulvihill JJ, Ferrell RE, Nath SK, Kamboh MI.

    BMC Med Genet. 2008 Jul 3;9:59.PMID: 18598350 [PubMed - indexed for MEDLINE]Related articlesFree article

    15.

    Quantitative trait analysis of type 2 diabetes susceptibility loci identified from whole genome association studies in the Insulin Resistance Atherosclerosis Family Study.

    Palmer ND, Goodarzi MO, Langefeld CD, Ziegler J, Norris JM, Haffner SM, Bryer-Ash M, Bergman RN, Wagenknecht LE, Taylor KD, Rotter JI, Bowden DW.

    Diabetes. 2008 Apr;57(4):1093-100. Epub 2008 Feb 5.PMID: 18252897 [PubMed - indexed for MEDLINE]Related articlesFree article

    16.

    Intact proinsulin, des 31,32 proinsulin, and specific insulin concentrations among nondiabetic and diabetic subjects in populations at varying risk of type 2 diabetes.

    Nagi DK, Knowler WC, Mohamed-Ali V, Bennett PH, Yudkin JS.

    Diabetes Care. 1998 Jan;21(1):127-33.PMID: 9538983 [PubMed - indexed for MEDLINE]Related articlesFree article

    17.

    Association of common genetic variation in the FOXO1 gene with beta-cell dysfunction, impaired glucose tolerance, and type 2 diabetes.

    Müssig K, Staiger H, Machicao F, Stancáková A, Kuusisto J, Laakso M, Thamer C, Machann J, Schick F, Claussen CD, Stefan N, Fritsche A, Häring HU.

    J Clin Endocrinol Metab. 2009 Apr;94(4):1353-60. Epub 2009 Jan 13.PMID: 19141580 [PubMed - indexed for MEDLINE]Related articles

    18.

    Association of GCKR rs780094, alone or in combination with GCK rs1799884, with type 2 diabetes and related traits in a Han Chinese population.

    Qi Q, Wu Y, Li H, Loos RJ, Hu FB, Sun L, Lu L, Pan A, Liu C, Wu H, Chen L, Yu Z, Lin X.

    Diabetologia. 2009 May;52(5):834-43. Epub 2009 Feb 25.PMID: 19241058 [PubMed - indexed for MEDLINE]Related articles

    19.

    The common P446L polymorphism in GCKR inversely modulates fasting glucose and triglyceride levels and reduces type 2 diabetes risk in the DESIR prospective general French population.

    Vaxillaire M, Cavalcanti-Proença C, Dechaume A, Tichet J, Marre M, Balkau B, Froguel P; DESIR Study Group.

    Diabetes. 2008 Aug;57(8):2253-7. Epub 2008 Jun 12.PMID: 18556336 [PubMed - indexed for MEDLINE]Related articlesFree article

    20.

    Common variants in CDKAL1, CDKN2A/B, IGF2BP2, SLC30A8, and HHEX/IDE genes are associated with type 2 diabetes and impaired fasting glucose in a Chinese Han population.

    Wu Y, Li H, Loos RJ, Yu Z, Ye X, Chen L, Pan A, Hu FB, Lin X.

    Diabetes. 2008 Oct;57(10):2834-42. Epub 2008 Jul 15.PMID: 18633108 [PubMed - indexed for MEDLINE]Related articlesFree article

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