PubMed

Interrogating type 2 diabetes genome-wide association data using a biological pathway-based approach.

Perry JR, McCarthy MI, Hattersley AT, Zeggini E; Wellcome Trust Case Control Consortium, Weedon MN, Frayling TM.

Diabetes. 2009 Jun;58(6):1463-7. Epub 2009 Feb 27.PMID: 19252133 [PubMed - indexed for MEDLINE]Related articlesFree article

Using genome-wide pathway analysis to unravel the etiology of complex diseases.

Elbers CC, van Eijk KR, Franke L, Mulder F, van der Schouw YT, Wijmenga C, Onland-Moret NC.

Genet Epidemiol. 2009 Jul;33(5):419-31.PMID: 19235186 [PubMed - indexed for MEDLINE]Related articles

Adiposity-related heterogeneity in patterns of type 2 diabetes susceptibility observed in genome-wide association data.

Timpson NJ, Lindgren CM, Weedon MN, Randall J, Ouwehand WH, Strachan DP, Rayner NW, Walker M, Hitman GA, Doney AS, Palmer CN, Morris AD, Hattersley AT, Zeggini E, Frayling TM, McCarthy MI.

Diabetes. 2009 Feb;58(2):505-10. Epub 2008 Dec 3.PMID: 19056611 [PubMed - indexed for MEDLINE]Related articlesFree article

Gene prioritization based on biological plausibility over genome wide association studies renders new loci associated with type 2 diabetes.

Sookoian S, Gianotti TF, Schuman M, Pirola CJ.

Genet Med. 2009 May;11(5):338-43.PMID: 19346957 [PubMed - indexed for MEDLINE]Related articles

Confirmation of multiple risk Loci and genetic impacts by a genome-wide association study of type 2 diabetes in the Japanese population.

Takeuchi F, Serizawa M, Yamamoto K, Fujisawa T, Nakashima E, Ohnaka K, Ikegami H, Sugiyama T, Katsuya T, Miyagishi M, Nakashima N, Nawata H, Nakamura J, Kono S, Takayanagi R, Kato N.

Diabetes. 2009 Jul;58(7):1690-9. Epub 2009 Apr 28.PMID: 19401414 [PubMed - indexed for MEDLINE]Related articlesFree article

Identification of type 2 diabetes genes in Mexican Americans through genome-wide association studies.

Hayes MG, Pluzhnikov A, Miyake K, Sun Y, Ng MC, Roe CA, Below JE, Nicolae RI, Konkashbaev A, Bell GI, Cox NJ, Hanis CL.

Diabetes. 2007 Dec;56(12):3033-44. Epub 2007 Sep 10.PMID: 17846124 [PubMed - indexed for MEDLINE]Related articlesFree article

Association analysis of variation in/near FTO, CDKAL1, SLC30A8, HHEX, EXT2, IGF2BP2, LOC387761, and CDKN2B with type 2 diabetes and related quantitative traits in Pima Indians.

Rong R, Hanson RL, Ortiz D, Wiedrich C, Kobes S, Knowler WC, Bogardus C, Baier LJ.

Diabetes. 2009 Feb;58(2):478-88. Epub 2008 Nov 13.PMID: 19008344 [PubMed - indexed for MEDLINE]Related articlesFree article

Genome-wide association scan for diabetic nephropathy susceptibility genes in type 1 diabetes.

Pezzolesi MG, Poznik GD, Mychaleckyj JC, Paterson AD, Barati MT, Klein JB, Ng DP, Placha G, Canani LH, Bochenski J, Waggott D, Merchant ML, Krolewski B, Mirea L, Wanic K, Katavetin P, Kure M, Wolkow P, Dunn JS, Smiles A, Walker WH, Boright AP, Bull SB; DCCT/EDIC Research Group, Doria A, Rogus JJ, Rich SS, Warram JH, Krolewski AS.

Diabetes. 2009 Jun;58(6):1403-10. Epub 2009 Feb 27.PMID: 19252134 [PubMed - indexed for MEDLINE]Related articlesFree article

Identification of novel candidate genes for type 2 diabetes from a genome-wide association scan in the Old Order Amish: evidence for replication from diabetes-related quantitative traits and from independent populations.

Rampersaud E, Damcott CM, Fu M, Shen H, McArdle P, Shi X, Shelton J, Yin J, Chang YP, Ott SH, Zhang L, Zhao Y, Mitchell BD, O'Connell J, Shuldiner AR.

Diabetes. 2007 Dec;56(12):3053-62. Epub 2007 Sep 10.PMID: 17846126 [PubMed - indexed for MEDLINE]Related articlesFree article

Association of transcription factor 7-like 2 (TCF7L2) variants with type 2 diabetes in a Finnish sample.

Scott LJ, Bonnycastle LL, Willer CJ, Sprau AG, Jackson AU, Narisu N, Duren WL, Chines PS, Stringham HM, Erdos MR, Valle TT, Tuomilehto J, Bergman RN, Mohlke KL, Collins FS, Boehnke M.

Diabetes. 2006 Sep;55(9):2649-53.PMID: 16936217 [PubMed - indexed for MEDLINE]Related articlesFree article

Strategies and issues in the detection of pathway enrichment in genome-wide association studies.

Hong MG, Pawitan Y, Magnusson PK, Prince JA.

Hum Genet. 2009 Aug;126(2):289-301. Epub 2009 May 1.PMID: 19408013 [PubMed - indexed for MEDLINE]Related articles

Follow-up analysis of genome-wide association data identifies novel loci for type 1 diabetes.

Grant SF, Qu HQ, Bradfield JP, Marchand L, Kim CE, Glessner JT, Grabs R, Taback SP, Frackelton EC, Eckert AW, Annaiah K, Lawson ML, Otieno FG, Santa E, Shaner JL, Smith RM, Skraban R, Imielinski M, Chiavacci RM, Grundmeier RW, Stanley CA, Kirsch SE, Waggott D, Paterson AD, Monos DS; DCCT/EDIC Research Group, Polychronakos C, Hakonarson H.

Diabetes. 2009 Jan;58(1):290-5. Epub 2008 Oct 7.PMID: 18840781 [PubMed - indexed for MEDLINE]Related articlesFree article

Haplotypic analysis of Wellcome Trust Case Control Consortium data.

Browning BL, Browning SR.

Hum Genet. 2008 Apr;123(3):273-80. Epub 2008 Jan 26.PMID: 18224336 [PubMed - indexed for MEDLINE]Related articlesFree article

Identification of susceptibility genes for complex diseases using pooling-based genome-wide association scans.

Bossé Y, Bacot F, Montpetit A, Rung J, Qu HQ, Engert JC, Polychronakos C, Hudson TJ, Froguel P, Sladek R, Desrosiers M.

Hum Genet. 2009 Apr;125(3):305-18. Epub 2009 Jan 29.PMID: 19184112 [PubMed - indexed for MEDLINE]Related articles

Genetic variation near the hepatocyte nuclear factor-4 alpha gene predicts susceptibility to type 2 diabetes.

Silander K, Mohlke KL, Scott LJ, Peck EC, Hollstein P, Skol AD, Jackson AU, Deloukas P, Hunt S, Stavrides G, Chines PS, Erdos MR, Narisu N, Conneely KN, Li C, Fingerlin TE, Dhanjal SK, Valle TT, Bergman RN, Tuomilehto J, Watanabe RM, Boehnke M, Collins FS.

Diabetes. 2004 Apr;53(4):1141-9.PMID: 15047633 [PubMed - indexed for MEDLINE]Related articlesFree article

Type 2 diabetes-associated genetic variants discovered in the recent genome-wide association studies are related to gestational diabetes mellitus in the Korean population.

Cho YM, Kim TH, Lim S, Choi SH, Shin HD, Lee HK, Park KS, Jang HC.

Diabetologia. 2009 Feb;52(2):253-61. Epub 2008 Nov 11.PMID: 19002430 [PubMed - indexed for MEDLINE]Related articles

Association of RASGRP1 with type 1 diabetes is revealed by combined follow-up of two genome-wide studies.

Qu HQ, Grant SF, Bradfield JP, Kim C, Frackelton E, Hakonarson H, Polychronakos C.

J Med Genet. 2009 Aug;46(8):553-4. Epub 2009 May 21.PMID: 19465406 [PubMed - indexed for MEDLINE]Related articles

Evaluating the association of common APOA2 variants with type 2 diabetes.

Duesing K, Charpentier G, Marre M, Tichet J, Hercberg S, Balkau B, Froguel P, Gibson F.

BMC Med Genet. 2009 Feb 13;10:13.PMID: 19216768 [PubMed - indexed for MEDLINE]Related articlesFree article

Evaluation of common variants in the six known maturity-onset diabetes of the young (MODY) genes for association with type 2 diabetes.

Winckler W, Weedon MN, Graham RR, McCarroll SA, Purcell S, Almgren P, Tuomi T, Gaudet D, Boström KB, Walker M, Hitman G, Hattersley AT, McCarthy MI, Ardlie KG, Hirschhorn JN, Daly MJ, Frayling TM, Groop L, Altshuler D.

Diabetes. 2007 Mar;56(3):685-93.PMID: 17327436 [PubMed - indexed for MEDLINE]Related articlesFree article

Evaluating the association of common PBX1 variants with type 2 diabetes.

Duesing K, Charpentier G, Marre M, Tichet J, Hercberg S, Balkau B, Froguel P, Gibson F.

BMC Med Genet. 2008 Feb 29;9:14.PMID: 18312624 [PubMed - indexed for MEDLINE]Related articlesFree article