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    Results: 1 to 20 of 101

    1.

    Hypoxia. HIF-mediated articular chondrocyte function: prospects for cartilage repair.

    Murphy CL, Thoms BL, Vaghjiani RJ, Lafont JE.

    Arthritis Res Ther. 2009;11(1):213. Epub 2009 Feb 5. Review.

    PMID:
    19232075
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    2.

    Hypoxia promotes the differentiated human articular chondrocyte phenotype through SOX9-dependent and -independent pathways.

    Lafont JE, Talma S, Hopfgarten C, Murphy CL.

    J Biol Chem. 2008 Feb 22;283(8):4778-86. Epub 2007 Dec 12.

    PMID:
    18077449
    [PubMed - indexed for MEDLINE]
    Free Article
    3.

    Lack of oxygen in articular cartilage: consequences for chondrocyte biology.

    Lafont JE.

    Int J Exp Pathol. 2010 Apr;91(2):99-106. Review. Erratum in: Int J Exp Pathol. 2010 Jun;91(3):302.

    PMID:
    20384821
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    4.

    Hypoxia-inducible factor 2alpha is essential for hypoxic induction of the human articular chondrocyte phenotype.

    Lafont JE, Talma S, Murphy CL.

    Arthritis Rheum. 2007 Oct;56(10):3297-306.

    PMID:
    17907154
    [PubMed - indexed for MEDLINE]
    Free Article
    5.

    Role of hypoxia-inducible factor-1 alpha in the regulation of plasminogen activator activity in rat knee joint chondrocytes.

    Zhu G, Tang Y, Liang X, Zheng M, Yang J, Zhou H, Li L, Qin T.

    Osteoarthritis Cartilage. 2009 Nov;17(11):1494-502. Epub 2009 May 19.

    PMID:
    19490965
    [PubMed - indexed for MEDLINE]
    6.

    Hypoxia-inducible factor 1alpha is involved in the prostaglandin metabolism of osteoarthritic cartilage through up-regulation of microsomal prostaglandin E synthase 1 in articular chondrocytes.

    Grimmer C, Pfander D, Swoboda B, Aigner T, Mueller L, Hennig FF, Gelse K.

    Arthritis Rheum. 2007 Dec;56(12):4084-94.

    PMID:
    18050215
    [PubMed - indexed for MEDLINE]
    Free Article
    7.

    Role of hypoxia-inducible factor 1 alpha in the integrity of articular cartilage in murine knee joints.

    Gelse K, Pfander D, Obier S, Knaup KX, Wiesener M, Hennig FF, Swoboda B.

    Arthritis Res Ther. 2008;10(5):R111. Epub 2008 Sep 12.

    PMID:
    18789153
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    8.

    Catabolic stress induces expression of hypoxia-inducible factor (HIF)-1 alpha in articular chondrocytes: involvement of HIF-1 alpha in the pathogenesis of osteoarthritis.

    Yudoh K, Nakamura H, Masuko-Hongo K, Kato T, Nishioka K.

    Arthritis Res Ther. 2005;7(4):R904-14. Epub 2005 May 27. Erratum in: Arthritis Res Ther. 2005;7(5):225.

    PMID:
    15987493
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    9.

    Tonic activation of hypoxia-inducible factor 1alpha in avascular articular cartilage and implications for metabolic homeostasis.

    Brucker PU, Izzo NJ, Chu CR.

    Arthritis Rheum. 2005 Oct;52(10):3181-91.

    PMID:
    16200622
    [PubMed - indexed for MEDLINE]
    Free Article
    10.

    The use of mesenchymal stem cells for chondrogenesis.

    Pelttari K, Steck E, Richter W.

    Injury. 2008 Apr;39 Suppl 1:S58-65. Review.

    PMID:
    18313473
    [PubMed - indexed for MEDLINE]
    11.

    Hypoxia inducible factor-1 and facilitative glucose transporters GLUT1 and GLUT3: putative molecular components of the oxygen and glucose sensing apparatus in articular chondrocytes.

    Mobasheri A, Richardson S, Mobasheri R, Shakibaei M, Hoyland JA.

    Histol Histopathol. 2005 Oct;20(4):1327-38. Review.

    PMID:
    16136514
    [PubMed - indexed for MEDLINE]
    12.

    Hypoxia inducible factor-1 alpha expression in human normal and osteoarthritic chondrocytes.

    Coimbra IB, Jimenez SA, Hawkins DF, Piera-Velazquez S, Stokes DG.

    Osteoarthritis Cartilage. 2004 Apr;12(4):336-45.

    PMID:
    15023385
    [PubMed - indexed for MEDLINE]
    13.

    Subtractive gene expression profiling of articular cartilage and mesenchymal stem cells: serpins as cartilage-relevant differentiation markers.

    Boeuf S, Steck E, Pelttari K, Hennig T, Buneb A, Benz K, Witte D, Sültmann H, Poustka A, Richter W.

    Osteoarthritis Cartilage. 2008 Jan;16(1):48-60. Epub 2007 Jul 2.

    PMID:
    17604188
    [PubMed - indexed for MEDLINE]
    14.

    Sustained hypoxia enhances chondrocyte matrix synthesis.

    Coyle CH, Izzo NJ, Chu CR.

    J Orthop Res. 2009 Jun;27(6):793-9.

    PMID:
    19051248
    [PubMed - indexed for MEDLINE]
    15.

    Osteoarthritic chondrocyte-secreted morphogens induce chondrogenic differentiation of human mesenchymal stem cells.

    Aung A, Gupta G, Majid G, Varghese S.

    Arthritis Rheum. 2011 Jan;63(1):148-58. doi: 10.1002/art.30086.

    PMID:
    20954186
    [PubMed - indexed for MEDLINE]
    Free Article
    16.

    Facilitative glucose transporters in articular chondrocytes. Expression, distribution and functional regulation of GLUT isoforms by hypoxia, hypoxia mimetics, growth factors and pro-inflammatory cytokines.

    Mobasheri A, Bondy CA, Moley K, Mendes AF, Rosa SC, Richardson SM, Hoyland JA, Barrett-Jolley R, Shakibaei M.

    Adv Anat Embryol Cell Biol. 2008;200:1 p following vi, 1-84. Review.

    PMID:
    18841755
    [PubMed - indexed for MEDLINE]
    17.

    Coculture of equine mesenchymal stem cells and mature equine articular chondrocytes results in improved chondrogenic differentiation of the stem cells.

    Lettry V, Hosoya K, Takagi S, Okumura M.

    Jpn J Vet Res. 2010 May;58(1):5-15.

    PMID:
    20645581
    [PubMed - indexed for MEDLINE]
    18.

    Age-related biological characterization of mesenchymal progenitor cells in human articular cartilage.

    Chang HX, Yang L, Li Z, Chen G, Dai G.

    Orthopedics. 2011 Aug 8;34(8):e382-8. doi: 10.3928/01477447-20110627-06.

    PMID:
    21815581
    [PubMed - indexed for MEDLINE]
    19.

    Hypoxia and osteoarthritis: how chondrocytes survive hypoxic environments.

    Pfander D, Gelse K.

    Curr Opin Rheumatol. 2007 Sep;19(5):457-62. Review.

    PMID:
    17762611
    [PubMed - indexed for MEDLINE]
    20.

    Effect of hypoxia and reoxygenation on gene expression and response to interleukin-1 in cultured articular chondrocytes.

    Martin G, Andriamanalijaona R, Grässel S, Dreier R, Mathy-Hartert M, Bogdanowicz P, Boumédiene K, Henrotin Y, Bruckner P, Pujol JP.

    Arthritis Rheum. 2004 Nov;50(11):3549-60.

    PMID:
    15529381
    [PubMed - indexed for MEDLINE]
    Free Article

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