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    Results: 1 to 20 of 100

    1.

    Genetic variation in the multidrug and toxin extrusion 1 transporter protein influences the glucose-lowering effect of metformin in patients with diabetes: a preliminary study.

    Becker ML, Visser LE, van Schaik RH, Hofman A, Uitterlinden AG, Stricker BH.

    Diabetes. 2009 Mar;58(3):745-9. Epub 2009 Feb 19.PMID: 19228809 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    Genetic variation in the organic cation transporter 1 is associated with metformin response in patients with diabetes mellitus.

    Becker ML, Visser LE, van Schaik RH, Hofman A, Uitterlinden AG, Stricker BH.

    Pharmacogenomics J. 2009 Aug;9(4):242-7. Epub 2009 Apr 21.PMID: 19381165 [PubMed - indexed for MEDLINE]Related articles

    3.

    Interaction between polymorphisms in the OCT1 and MATE1 transporter and metformin response.

    Becker ML, Visser LE, van Schaik RH, Hofman A, Uitterlinden AG, Stricker BH.

    Pharmacogenet Genomics. 2009 Nov 5. [Epub ahead of print]PMID: 19898263 [PubMed - as supplied by publisher]Related articles

    4.

    Reduced-function SLC22A1 polymorphisms encoding organic cation transporter 1 and glycemic response to metformin: a GoDARTS study.

    Zhou K, Donnelly LA, Kimber CH, Donnan PT, Doney AS, Leese G, Hattersley AT, McCarthy MI, Morris AD, Palmer CN, Pearson ER.

    Diabetes. 2009 Jun;58(6):1434-9. Epub 2009 Mar 31.PMID: 19336679 [PubMed - indexed for MEDLINE]Related articlesFree article

    5.

    Effect of genetic variation in the organic cation transporter 2 on the renal elimination of metformin.

    Chen Y, Li S, Brown C, Cheatham S, Castro RA, Leabman MK, Urban TJ, Chen L, Yee SW, Choi JH, Huang Y, Brett CM, Burchard EG, Giacomini KM.

    Pharmacogenet Genomics. 2009 Jul;19(7):497-504.PMID: 19483665 [PubMed - indexed for MEDLINE]Related articles

    6.

    Targeted disruption of the multidrug and toxin extrusion 1 (mate1) gene in mice reduces renal secretion of metformin.

    Tsuda M, Terada T, Mizuno T, Katsura T, Shimakura J, Inui K.

    Mol Pharmacol. 2009 Jun;75(6):1280-6. Epub 2009 Mar 30.PMID: 19332510 [PubMed - indexed for MEDLINE]Related articles

    7.

    OCT2 polymorphisms and in-vivo renal functional consequence: studies with metformin and cimetidine.

    Wang ZJ, Yin OQ, Tomlinson B, Chow MS.

    Pharmacogenet Genomics. 2008 Jul;18(7):637-45.PMID: 18551044 [PubMed - indexed for MEDLINE]Related articles

    8.

    Involvement of human multidrug and toxin extrusion 1 in the drug interaction between cimetidine and metformin in renal epithelial cells.

    Tsuda M, Terada T, Ueba M, Sato T, Masuda S, Katsura T, Inui K.

    J Pharmacol Exp Ther. 2009 Apr;329(1):185-91. Epub 2009 Jan 22.PMID: 19164462 [PubMed - indexed for MEDLINE]Related articles

    9.

    Human organic cation transporter (OCT1 and OCT2) gene polymorphisms and therapeutic effects of metformin.

    Shikata E, Yamamoto R, Takane H, Shigemasa C, Ikeda T, Otsubo K, Ieiri I.

    J Hum Genet. 2007;52(2):117-22. Epub 2006 Nov 17.PMID: 17111267 [PubMed - indexed for MEDLINE]Related articles

    10.

    The effects of genetic polymorphisms in the organic cation transporters OCT1, OCT2, and OCT3 on the renal clearance of metformin.

    Tzvetkov MV, Vormfelde SV, Balen D, Meineke I, Schmidt T, Sehrt D, Sabolić I, Koepsell H, Brockmöller J.

    Clin Pharmacol Ther. 2009 Sep;86(3):299-306. Epub 2009 Jun 17.PMID: 19536068 [PubMed - indexed for MEDLINE]Related articles

    11.

    Functional characterization of the human organic cation transporter 2 variant p.270Ala>Ser.

    Zolk O, Solbach TF, König J, Fromm MF.

    Drug Metab Dispos. 2009 Jun;37(6):1312-8. Epub 2009 Feb 27.PMID: 19251820 [PubMed - indexed for MEDLINE]Related articles

    12.

    Polymorphism in human organic cation transporters and metformin action.

    Takane H, Shikata E, Otsubo K, Higuchi S, Ieiri I.

    Pharmacogenomics. 2008 Apr;9(4):415-22. Review.PMID: 18384255 [PubMed - indexed for MEDLINE]Related articles

    13.

    Expression of organic cation transporters OCT1 (SLC22A1) and OCT3 (SLC22A3) is affected by genetic factors and cholestasis in human liver.

    Nies AT, Koepsell H, Winter S, Burk O, Klein K, Kerb R, Zanger UM, Keppler D, Schwab M, Schaeffeler E.

    Hepatology. 2009 Oct;50(4):1227-40.PMID: 19591196 [PubMed - indexed for MEDLINE]Related articles

    14.

    Metformin is a superior substrate for renal organic cation transporter OCT2 rather than hepatic OCT1.

    Kimura N, Masuda S, Tanihara Y, Ueo H, Okuda M, Katsura T, Inui K.

    Drug Metab Pharmacokinet. 2005 Oct;20(5):379-86.PMID: 16272756 [PubMed - indexed for MEDLINE]Related articlesFree article

    15.

    Association of variants in RETN with plasma resistin levels and diabetes-related traits in the Framingham Offspring Study.

    Hivert MF, Manning AK, McAteer JB, Dupuis J, Fox CS, Cupples LA, Meigs JB, Florez JC.

    Diabetes. 2009 Mar;58(3):750-6. Epub 2008 Dec 15.PMID: 19074981 [PubMed - indexed for MEDLINE]Related articlesFree article

    16.

    Genetic variants of the organic cation transporter 2 influence the disposition of metformin.

    Song IS, Shin HJ, Shim EJ, Jung IS, Kim WY, Shon JH, Shin JG.

    Clin Pharmacol Ther. 2008 Nov;84(5):559-62. Epub 2008 Apr 9.PMID: 18401339 [PubMed - indexed for MEDLINE]Related articles

    17.

    Common variation in the NOS1AP gene is associated with reduced glucose-lowering effect and with increased mortality in users of sulfonylurea.

    Becker ML, Aarnoudse AJ, Newton-Cheh C, Hofman A, Witteman JC, Uitterlinden AG, Visser LE, Stricker BH.

    Pharmacogenet Genomics. 2008 Jul;18(7):591-7.PMID: 18551039 [PubMed - indexed for MEDLINE]Related articles

    18.

    Genetic variants in multidrug and toxic compound extrusion-1, hMATE1, alter transport function.

    Chen Y, Teranishi K, Li S, Yee SW, Hesselson S, Stryke D, Johns SJ, Ferrin TE, Kwok P, Giacomini KM.

    Pharmacogenomics J. 2009 Apr;9(2):127-36. Epub 2009 Jan 27.PMID: 19172157 [PubMed - indexed for MEDLINE]Related articles

    19.

    Improvements in glycemic control in type 2 diabetes patients switched from sulfonylurea coadministered with metformin to glyburide-metformin tablets.

    Duckworth W, Marcelli M, Padden M, Kellick K, Duhancik T, Wilhardt M, Colgan K, Romie A.

    J Manag Care Pharm. 2003 May-Jun;9(3):256-62.PMID: 14613469 [PubMed - indexed for MEDLINE]Related articlesFree article

    20.

    Inflammation, insulin resistance, and diabetes--Mendelian randomization using CRP haplotypes points upstream.

    Brunner EJ, Kivimäki M, Witte DR, Lawlor DA, Davey Smith G, Cooper JA, Miller M, Lowe GD, Rumley A, Casas JP, Shah T, Humphries SE, Hingorani AD, Marmot MG, Timpson NJ, Kumari M.

    PLoS Med. 2008 Aug 12;5(8):e155.PMID: 18700811 [PubMed - indexed for MEDLINE]Related articlesFree article

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