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    Results: 1 to 20 of 97

    1.

    Recombinant human activated protein C in acute lung injury: what is the role of bronchial circulation?

    Maybauer MO, Traber DL, Maybauer DM.

    Crit Care. 2009;13(1):112. Epub 2009 Jan 23.PMID: 19226431 [PubMed - in process]Related articles

    2.

    Effects of recombinant human activated protein C in human models of endotoxin administration.

    Abraham E.

    Proc Am Thorac Soc. 2005;2(3):243-7. Review.PMID: 16222045 [PubMed - indexed for MEDLINE]Related articlesFree article

    3.

    Recombinant human activated protein C improves pulmonary function in ovine acute lung injury resulting from smoke inhalation and sepsis.

    Maybauer MO, Maybauer DM, Fraser JF, Traber LD, Westphal M, Enkhbaatar P, Cox RA, Huda R, Hawkins HK, Morita N, Murakami K, Mizutani A, Herndon DN, Traber DL.

    Crit Care Med. 2006 Sep;34(9):2432-8.PMID: 16810106 [PubMed - indexed for MEDLINE]Related articles

    4.

    Recombinant human activated protein C ameliorates oleic acid-induced lung injury in awake sheep.

    Waerhaug K, Kirov MY, Kuzkov VV, Kuklin VN, Bjertnaes LJ.

    Crit Care. 2008;12(6):R146. Epub 2008 Nov 20.PMID: 19021914 [PubMed - indexed for MEDLINE]Related articlesFree article

    5.

    Recombinant human activated protein C attenuates endotoxin-induced lung injury in awake sheep.

    Waerhaug K, Kuklin VN, Kirov MY, Sovershaev MA, Langbakk B, Ingebretsen OC, Ytrehus K, Bjertnaes LJ.

    Crit Care. 2008;12(4):R104. Epub 2008 Aug 15.PMID: 18702832 [PubMed - indexed for MEDLINE]Related articlesFree article

    6.

    Intravenous administration of activated protein C in Pseudomonas-induced lung injury: impact on lung fluid balance and the inflammatory response.

    Robriquet L, Collet F, Tournoys A, Prangère T, Nevière R, Fourrier F, Guery BP.

    Respir Res. 2006 Mar 22;7:41.PMID: 16553944 [PubMed - indexed for MEDLINE]Related articlesFree article

    7.

    Recombinant human activated protein C: current insights into its mechanism of action.

    Levi M, van der Poll T.

    Crit Care. 2007;11 Suppl 5:S3. Review.PMID: 18269690 [PubMed - indexed for MEDLINE]Related articlesFree article

    8.

    Recombinant human activated protein C reduces human endotoxin-induced pulmonary inflammation via inhibition of neutrophil chemotaxis.

    Nick JA, Coldren CD, Geraci MW, Poch KR, Fouty BW, O'Brien J, Gruber M, Zarini S, Murphy RC, Kuhn K, Richter D, Kast KR, Abraham E.

    Blood. 2004 Dec 15;104(13):3878-85. Epub 2004 Aug 31. Erratum in: Blood. 2005 May 15;105(10):3785. PMID: 15339848 [PubMed - indexed for MEDLINE]Related articlesFree article

    9.

    Anticoagulant therapy in acute lung injury: a useful tool without proper operating instruction?

    Rehberg S, Enkhbaatar P, Traber DL.

    Crit Care. 2008;12(5):179. Epub 2008 Sep 22.PMID: 18828885 [PubMed - indexed for MEDLINE]Related articlesFree article

    10.

    Early goal-directed therapy, corticosteroid, and recombinant human activated protein C for the treatment of severe sepsis and septic shock in the emergency department.

    Nguyen HB, Corbett SW, Menes K, Cho T, Daugharthy J, Klein W, Wittlake WA.

    Acad Emerg Med. 2006 Jan;13(1):109-13. Epub 2005 Dec 19.PMID: 16365336 [PubMed - indexed for MEDLINE]Related articles

    11.

    Cost-effectiveness of recombinant human activated protein C and the influence of severity of illness in the treatment of patients with severe sepsis.

    Fowler RA, Hill-Popper M, Stasinos J, Petrou C, Sanders GD, Garber AM.

    J Crit Care. 2003 Sep;18(3):181-91; discussion 191-4.PMID: 14595571 [PubMed - indexed for MEDLINE]Related articles

    12.

    Clinical and laboratory effects of recombinant human activated protein C in the treatment of a patient with sepsis-induced multiple organ failure.

    Brueckmann M, Wizenmann J, Hoffmann U, Seeger M, Bewig B.

    Thromb Res. 2003 Mar 15;109(5-6):259-63.PMID: 12818248 [PubMed - indexed for MEDLINE]Related articles

    13.

    Recombinant human activated protein C for severe sepsis in neonates.

    Kylat RI, Ohlsson A.

    Cochrane Database Syst Rev. 2006 Apr 19;(2):CD005385. Review.PMID: 16625638 [PubMed - indexed for MEDLINE]Related articles

    14.

    Activated protein C in sepsis: a critical review.

    Levi M.

    Curr Opin Hematol. 2008 Sep;15(5):481-6. Review.PMID: 18695371 [PubMed - indexed for MEDLINE]Related articles

    15.

    Recombinant human activated protein C (rhAPC; drotrecogin alfa [activated]) has minimal effect on markers of coagulation, fibrinolysis, and inflammation in acute human endotoxemia.

    Derhaschnig U, Reiter R, Knöbl P, Baumgartner M, Keen P, Jilma B.

    Blood. 2003 Sep 15;102(6):2093-8. Epub 2003 May 15.PMID: 12750166 [PubMed - indexed for MEDLINE]Related articlesFree article

    16.

    Recombinant human activated protein C upregulates cyclooxygenase-2 expression in endothelial cells via binding to endothelial cell protein C receptor and activation of protease-activated receptor-1.

    Brueckmann M, Horn S, Lang S, Fukudome K, Schulze Nahrup A, Hoffmann U, Kaden JJ, Borggrefe M, Haase KK, Huhle G.

    Thromb Haemost. 2005 Apr;93(4):743-50.PMID: 15841323 [PubMed - indexed for MEDLINE]Related articles

    17.

    Recombinant human activated protein C resets thrombin generation in patients with severe sepsis - a case control study.

    de Pont AC, Bakhtiari K, Hutten BA, de Jonge E, Vroom MB, Meijers JC, Büller HR, Levi M.

    Crit Care. 2005 Oct 5;9(5):R490-7. Epub 2005 Jul 21.PMID: 16277710 [PubMed - indexed for MEDLINE]Related articlesFree article

    18.

    Inhaled activated protein C attenuates lung injury induced by aerosolized endotoxin in mice.

    Kotanidou A, Loutrari H, Papadomichelakis E, Glynos C, Magkou C, Armaganidis A, Papapetropoulos A, Roussos C, Orfanos SE.

    Vascul Pharmacol. 2006 Aug;45(2):134-40. Epub 2006 Jul 25.PMID: 16959545 [PubMed - indexed for MEDLINE]Related articles

    19.

    Drotrecogin alfa activated (recombinant human activated protein C) in combination with heparin or melagatran: effects on prothrombin time and activated partial thromboplastin time.

    Koestenberger M, Cvirn G, Gallistl S, Muntean W.

    Blood Coagul Fibrinolysis. 2004 Oct;15(8):693-7.PMID: 15613925 [PubMed - indexed for MEDLINE]Related articles

    20.

    Prognostic value of platelet-derived growth factor in patients with severe sepsis.

    Brueckmann M, Hoffmann U, Engelhardt C, Lang S, Fukudome K, Haase KK, Liebe V, Kaden JJ, Putensen C, Borggrefe M, Huhle G.

    Growth Factors. 2007 Feb;25(1):15-24.PMID: 17454146 [PubMed - indexed for MEDLINE]Related articles

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