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    Results: 1 to 20 of 99

    1.

    Use of high-density tiling microarrays to identify mutations globally and elucidate mechanisms of drug resistance in Plasmodium falciparum.

    Dharia NV, Sidhu AB, Cassera MB, Westenberger SJ, Bopp SE, Eastman RT, Plouffe D, Batalov S, Park DJ, Volkman SK, Wirth DF, Zhou Y, Fidock DA, Winzeler EA.

    Genome Biol. 2009 Feb 13;10(2):R21.

    PMID:
    19216790
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    2.

    Detection of genome-wide polymorphisms in the AT-rich Plasmodium falciparum genome using a high-density microarray.

    Jiang H, Yi M, Mu J, Zhang L, Ivens A, Klimczak LJ, Huyen Y, Stephens RM, Su XZ.

    BMC Genomics. 2008 Aug 25;9:398.

    PMID:
    18724869
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    3.

    Field-based evidence of fast and global increase of Plasmodium falciparum drug-resistance by DNA-microarrays and PCR/RFLP in Niger.

    Ibrahim ML, Steenkeste N, Khim N, Adam HH, Konaté L, Coppée JY, Ariey F, Duchemin JB.

    Malar J. 2009 Feb 23;8:32.

    PMID:
    19236701
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    4.

    Mefloquine resistance in Plasmodium falciparum and increased pfmdr1 gene copy number.

    Price RN, Uhlemann AC, Brockman A, McGready R, Ashley E, Phaipun L, Patel R, Laing K, Looareesuwan S, White NJ, Nosten F, Krishna S.

    Lancet. 2004 Jul 31-Aug 6;364(9432):438-47.

    PMID:
    15288742
    [PubMed - indexed for MEDLINE]
    5.

    A systematic map of genetic variation in Plasmodium falciparum.

    Kidgell C, Volkman SK, Daily J, Borevitz JO, Plouffe D, Zhou Y, Johnson JR, Le Roch K, Sarr O, Ndir O, Mboup S, Batalov S, Wirth DF, Winzeler EA.

    PLoS Pathog. 2006 Jun;2(6):e57. Epub 2006 Jun 23. Erratum in: PLoS Pathog. 2006 Aug;2(8):e96.

    PMID:
    16789840
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    6.

    Geographical distribution of selected and putatively neutral SNPs in Southeast Asian malaria parasites.

    Anderson TJ, Nair S, Sudimack D, Williams JT, Mayxay M, Newton PN, Guthmann JP, Smithuis FM, Tran TH, van den Broek IV, White NJ, Nosten F.

    Mol Biol Evol. 2005 Dec;22(12):2362-74. Epub 2005 Aug 10.

    PMID:
    16093566
    [PubMed - indexed for MEDLINE]
    Free Article
    7.

    Proteomic approaches to studying drug targets and resistance in Plasmodium.

    Cooper RA, Carucci DJ.

    Curr Drug Targets Infect Disord. 2004 Mar;4(1):41-51. Review.

    PMID:
    15032633
    [PubMed - indexed for MEDLINE]
    8.

    Heterogeneous distribution of Plasmodium falciparum drug resistance haplotypes in subsets of the host population.

    Schoepflin S, Marfurt J, Goroti M, Baisor M, Mueller I, Felger I.

    Malar J. 2008 May 6;7:78.

    PMID:
    18460212
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    9.

    Regulatory hotspots in the malaria parasite genome dictate transcriptional variation.

    Gonzales JM, Patel JJ, Ponmee N, Jiang L, Tan A, Maher SP, Wuchty S, Rathod PK, Ferdig MT.

    PLoS Biol. 2008 Sep 30;6(9):e238.

    PMID:
    18828674
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    10.

    A second target of the antimalarial and antibacterial agent fosmidomycin revealed by cellular metabolic profiling.

    Zhang B, Watts KM, Hodge D, Kemp LM, Hunstad DA, Hicks LM, Odom AR.

    Biochemistry. 2011 May 3;50(17):3570-7. Epub 2011 Apr 11.

    PMID:
    21438569
    [PubMed - indexed for MEDLINE]
    11.

    A multiplex ligase detection reaction-fluorescent microsphere assay for simultaneous detection of single nucleotide polymorphisms associated with Plasmodium falciparum drug resistance.

    Carnevale EP, Kouri D, DaRe JT, McNamara DT, Mueller I, Zimmerman PA.

    J Clin Microbiol. 2007 Mar;45(3):752-61. Epub 2006 Nov 22.

    PMID:
    17121999
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    12.

    Recurrent gene amplification and soft selective sweeps during evolution of multidrug resistance in malaria parasites.

    Nair S, Nash D, Sudimack D, Jaidee A, Barends M, Uhlemann AC, Krishna S, Nosten F, Anderson TJ.

    Mol Biol Evol. 2007 Feb;24(2):562-73. Epub 2006 Nov 23.

    PMID:
    17124182
    [PubMed - indexed for MEDLINE]
    Free Article
    13.

    Validation of isoleucine utilization targets in Plasmodium falciparum.

    Istvan ES, Dharia NV, Bopp SE, Gluzman I, Winzeler EA, Goldberg DE.

    Proc Natl Acad Sci U S A. 2011 Jan 25;108(4):1627-32. Epub 2011 Jan 4.

    PMID:
    21205898
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    14.

    Drug resistance and genetic mapping in Plasmodium falciparum.

    Hayton K, Su XZ.

    Curr Genet. 2008 Nov;54(5):223-39. Epub 2008 Sep 18. Review.

    PMID:
    18802698
    [PubMed - indexed for MEDLINE]
    15.

    Identification and functional validation of the novel antimalarial resistance locus PF10_0355 in Plasmodium falciparum.

    Van Tyne D, Park DJ, Schaffner SF, Neafsey DE, Angelino E, Cortese JF, Barnes KG, Rosen DM, Lukens AK, Daniels RF, Milner DA Jr, Johnson CA, Shlyakhter I, Grossman SR, Becker JS, Yamins D, Karlsson EK, Ndiaye D, Sarr O, Mboup S, Happi C, Furlotte NA, Eskin E, Kang HM, Hartl DL, Birren BW, Wiegand RC, Lander ES, Wirth DF, Volkman SK, Sabeti PC.

    PLoS Genet. 2011 Apr;7(4):e1001383. Epub 2011 Apr 21.

    PMID:
    21533027
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    16.

    Functional analysis of drug resistance in Plasmodium falciparum in the post-genomic era.

    Cowman AF.

    Int J Parasitol. 2001 Jul;31(9):871-8. Review.

    PMID:
    11406136
    [PubMed - indexed for MEDLINE]
    17.

    Plasmodium falciparum genome-wide scans for positive selection, recombination hot spots and resistance to antimalarial drugs.

    Mu J, Myers RA, Jiang H, Liu S, Ricklefs S, Waisberg M, Chotivanich K, Wilairatana P, Krudsood S, White NJ, Udomsangpetch R, Cui L, Ho M, Ou F, Li H, Song J, Li G, Wang X, Seila S, Sokunthea S, Socheat D, Sturdevant DE, Porcella SF, Fairhurst RM, Wellems TE, Awadalla P, Su XZ.

    Nat Genet. 2010 Mar;42(3):268-71. Epub 2010 Jan 31.

    PMID:
    20101240
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    18.

    Rapid microarray-based method for monitoring of all currently known single-nucleotide polymorphisms associated with parasite resistance to antimalaria drugs.

    Crameri A, Marfurt J, Mugittu K, Maire N, Regös A, Coppee JY, Sismeiro O, Burki R, Huber E, Laubscher D, Puijalon O, Genton B, Felger I, Beck HP.

    J Clin Microbiol. 2007 Nov;45(11):3685-91. Epub 2007 Sep 5.

    PMID:
    17804664
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    19.

    In vitro and in vivo synergy of fosmidomycin, a novel antimalarial drug, with clindamycin.

    Wiesner J, Henschker D, Hutchinson DB, Beck E, Jomaa H.

    Antimicrob Agents Chemother. 2002 Sep;46(9):2889-94.

    PMID:
    12183243
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    20.

    In vitro assessment of artesunate, artemether and amodiaquine susceptibility and molecular analysis of putative resistance-associated mutations of Plasmodium falciparum from São Tomé and Príncipe.

    Ferreira ID, Lopes D, Martinelli A, Ferreira C, do Rosário VE, Cravo P.

    Trop Med Int Health. 2007 Mar;12(3):353-62.

    PMID:
    17313506
    [PubMed - indexed for MEDLINE]
    Free Article

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