PubMed

APOBEC3G induces a hypermutation gradient: purifying selection at multiple steps during HIV-1 replication results in levels of G-to-A mutations that are high in DNA, intermediate in cellular viral RNA, and low in virion RNA.

Russell RA, Moore MD, Hu WS, Pathak VK.

Retrovirology. 2009 Feb 13;6:16.PMID: 19216784 [PubMed - indexed for MEDLINE]Related articlesFree article

Target cell APOBEC3C can induce limited G-to-A mutation in HIV-1.

Bourara K, Liegler TJ, Grant RM.

PLoS Pathog. 2007 Oct 26;3(10):1477-85.PMID: 17967058 [PubMed - indexed for MEDLINE]Related articlesFree article

Intracellular interactions between APOBEC3G, RNA, and HIV-1 Gag: APOBEC3G multimerization is dependent on its association with RNA.

Friew YN, Boyko V, Hu WS, Pathak VK.

Retrovirology. 2009 Jun 4;6:56.PMID: 19497112 [PubMed - indexed for MEDLINE]Related articlesFree article

Regulation of Vif mRNA splicing by human immunodeficiency virus type 1 requires 5' splice site D2 and an exonic splicing enhancer to counteract cellular restriction factor APOBEC3G.

Mandal D, Exline CM, Feng Z, Stoltzfus CM.

J Virol. 2009 Jun;83(12):6067-78. Epub 2009 Apr 8.PMID: 19357165 [PubMed - indexed for MEDLINE]Related articlesFree article

The antiviral factor APOBEC3G improves CTL recognition of cultured HIV-infected T cells.

Casartelli N, Guivel-Benhassine F, Bouziat R, Brandler S, Schwartz O, Moris A.

J Exp Med. 2010 Jan 18;207(1):39-49, S1-2. Epub 2009 Dec 28.PMID: 20038599 [PubMed - indexed for MEDLINE]Related articles

Vpr14-88-Apobec3G fusion protein is efficiently incorporated into Vif-positive HIV-1 particles and inhibits viral infection.

Ao Z, Yu Z, Wang L, Zheng Y, Yao X.

PLoS One. 2008 Apr 16;3(4):e1995.PMID: 18414671 [PubMed - indexed for MEDLINE]Related articlesFree article

The cytidine deaminase CEM15 induces hypermutation in newly synthesized HIV-1 DNA.

Zhang H, Yang B, Pomerantz RJ, Zhang C, Arunachalam SC, Gao L.

Nature. 2003 Jul 3;424(6944):94-8. Epub 2003 May 28.PMID: 12808465 [PubMed - indexed for MEDLINE]Related articlesFree article

Human immunodeficiency virus type 1 cDNAs produced in the presence of APOBEC3G exhibit defects in plus-strand DNA transfer and integration.

Mbisa JL, Barr R, Thomas JA, Vandegraaff N, Dorweiler IJ, Svarovskaia ES, Brown WL, Mansky LM, Gorelick RJ, Harris RS, Engelman A, Pathak VK.

J Virol. 2007 Jul;81(13):7099-110. Epub 2007 Apr 11.PMID: 17428871 [PubMed - indexed for MEDLINE]Related articlesFree article

Inhibition of HIV-1 infection and replication by enhancing viral incorporation of innate anti-HIV-1 protein A3G: a non-pathogenic Nef mutant-based anti-HIV strategy.

Green LA, Liu Y, He JJ.

J Biol Chem. 2009 May 15;284(20):13363-72. Epub 2009 Mar 26.PMID: 19324886 [PubMed - indexed for MEDLINE]Related articles

APOBEC3G and APOBEC3F require an endogenous cofactor to block HIV-1 replication.

Han Y, Wang X, Dang Y, Zheng YH.

PLoS Pathog. 2008 Jul 4;4(7):e1000095.PMID: 18604271 [PubMed - indexed for MEDLINE]Related articlesFree article

Human apolipoprotein B mRNA-editing enzyme-catalytic polypeptide-like 3G (APOBEC3G) is incorporated into HIV-1 virions through interactions with viral and nonviral RNAs.

Svarovskaia ES, Xu H, Mbisa JL, Barr R, Gorelick RJ, Ono A, Freed EO, Hu WS, Pathak VK.

J Biol Chem. 2004 Aug 20;279(34):35822-8. Epub 2004 Jun 20.PMID: 15210704 [PubMed - indexed for MEDLINE]Related articlesFree article

A single amino acid substitution in human APOBEC3G antiretroviral enzyme confers resistance to HIV-1 virion infectivity factor-induced depletion.

Xu H, Svarovskaia ES, Barr R, Zhang Y, Khan MA, Strebel K, Pathak VK.

Proc Natl Acad Sci U S A. 2004 Apr 13;101(15):5652-7. Epub 2004 Mar 30.PMID: 15054139 [PubMed - indexed for MEDLINE]Related articlesFree article

Exosomes packaging APOBEC3G confer human immunodeficiency virus resistance to recipient cells.

Khatua AK, Taylor HE, Hildreth JE, Popik W.

J Virol. 2009 Jan;83(2):512-21. Epub 2008 Nov 5.PMID: 18987139 [PubMed - indexed for MEDLINE]Related articlesFree article

The HIV-1 Vif PPLP motif is necessary for human APOBEC3G binding and degradation.

Donahue JP, Vetter ML, Mukhtar NA, D'Aquila RT.

Virology. 2008 Jul 20;377(1):49-53. Epub 2008 May 21.PMID: 18499212 [PubMed - indexed for MEDLINE]Related articlesFree article

Distinct viral determinants for the packaging of human cytidine deaminases APOBEC3G and APOBEC3C.

Wang T, Zhang W, Tian C, Liu B, Yu Y, Ding L, Spearman P, Yu XF.

Virology. 2008 Jul 20;377(1):71-9. Epub 2008 May 21.PMID: 18495196 [PubMed - indexed for MEDLINE]Related articlesFree article

Human immunodeficiency virus type 1 replication and regulation of APOBEC3G by peptidyl prolyl isomerase Pin1.

Watashi K, Khan M, Yedavalli VR, Yeung ML, Strebel K, Jeang KT.

J Virol. 2008 Oct;82(20):9928-36. Epub 2008 Aug 6.PMID: 18684817 [PubMed - indexed for MEDLINE]Related articlesFree article

The human immunodeficiency virus type 1 Vif protein reduces intracellular expression and inhibits packaging of APOBEC3G (CEM15), a cellular inhibitor of virus infectivity.

Kao S, Khan MA, Miyagi E, Plishka R, Buckler-White A, Strebel K.

J Virol. 2003 Nov;77(21):11398-407.PMID: 14557625 [PubMed - indexed for MEDLINE]Related articlesFree article

APOBEC3G-independent reduction in virion infectivity during long-term HIV-1 replication in terminally differentiated macrophages.

Miyagi E, Schwartzkopff F, Plishka R, Buckler-White A, Clouse KA, Strebel K.

Virology. 2008 Sep 30;379(2):266-74. Epub 2008 Aug 3.PMID: 18675436 [PubMed - indexed for MEDLINE]Related articlesFree article

Hypermutation by intersegmental transfer of APOBEC3G cytidine deaminase.

Nowarski R, Britan-Rosich E, Shiloach T, Kotler M.

Nat Struct Mol Biol. 2008 Oct;15(10):1059-66. Epub 2008 Sep 28.PMID: 18820687 [PubMed - indexed for MEDLINE]Related articles

APOBEC3G inhibits elongation of HIV-1 reverse transcripts.

Bishop KN, Verma M, Kim EY, Wolinsky SM, Malim MH.

PLoS Pathog. 2008 Dec;4(12):e1000231. Epub 2008 Dec 5.PMID: 19057663 [PubMed - indexed for MEDLINE]Related articlesFree article