PubMed

Interleukin-21 is required for the development of type 1 diabetes in NOD mice.

Sutherland AP, Van Belle T, Wurster AL, Suto A, Michaud M, Zhang D, Grusby MJ, von Herrath M.

Diabetes. 2009 May;58(5):1144-55. Epub 2009 Feb 10.PMID: 19208913 [PubMed - indexed for MEDLINE]Related articlesFree article

Monocyte chemoattractant protein-1 is expressed in pancreatic islets from prediabetic NOD mice and in interleukin-1 beta-exposed human and rat islet cells.

Chen MC, Proost P, Gysemans C, Mathieu C, Eizirik DL.

Diabetologia. 2001 Mar;44(3):325-32.PMID: 11317664 [PubMed - indexed for MEDLINE]Related articles

IL-12 administration accelerates autoimmune diabetes in both wild-type and IFN-gamma-deficient nonobese diabetic mice, revealing pathogenic and protective effects of IL-12-induced IFN-gamma.

Trembleau S, Penna G, Gregori S, Giarratana N, Adorini L.

J Immunol. 2003 Jun 1;170(11):5491-501.PMID: 12759426 [PubMed - indexed for MEDLINE]Related articlesFree article

IL-1 receptor deficiency slows progression to diabetes in the NOD mouse.

Thomas HE, Irawaty W, Darwiche R, Brodnicki TC, Santamaria P, Allison J, Kay TW.

Diabetes. 2004 Jan;53(1):113-21.PMID: 14693705 [PubMed - indexed for MEDLINE]Related articlesFree article

Pancreas-infiltrating Th1 cells and diabetes develop in IL-12-deficient nonobese diabetic mice.

Trembleau S, Penna G, Gregori S, Chapman HD, Serreze DV, Magram J, Adorini L.

J Immunol. 1999 Sep 1;163(5):2960-8.PMID: 10453045 [PubMed - indexed for MEDLINE]Related articlesFree article

Islet-specific expression of IL-10 promotes diabetes in nonobese diabetic mice independent of Fas, perforin, TNF receptor-1, and TNF receptor-2 molecules.

Balasa B, Van Gunst K, Jung N, Balakrishna D, Santamaria P, Hanafusa T, Itoh N, Sarvetnick N.

J Immunol. 2000 Sep 1;165(5):2841-9.PMID: 10946317 [PubMed - indexed for MEDLINE]Related articlesFree article

Disease resistant, NOD-related strains reveal checkpoints of immunoregulation in the pancreas.

Rothe H, Ito Y, Kolb H.

J Mol Med. 2001 May;79(4):190-7.PMID: 11409710 [PubMed - indexed for MEDLINE]Related articles

Suppressor of cytokine signaling-1 overexpression protects pancreatic beta cells from CD8+ T cell-mediated autoimmune destruction.

Chong MM, Chen Y, Darwiche R, Dudek NL, Irawaty W, Santamaria P, Allison J, Kay TW, Thomas HE.

J Immunol. 2004 May 1;172(9):5714-21.PMID: 15100317 [PubMed - indexed for MEDLINE]Related articlesFree article

Essential role for signal transducer and activator of transcription-1 in pancreatic beta-cell death and autoimmune type 1 diabetes of nonobese diabetic mice.

Kim S, Kim HS, Chung KW, Oh SH, Yun JW, Im SH, Lee MK, Kim KW, Lee MS.

Diabetes. 2007 Oct;56(10):2561-8. Epub 2007 Jul 9.PMID: 17620422 [PubMed - indexed for MEDLINE]Related articlesFree article

An update on cytokines in the pathogenesis of insulin-dependent diabetes mellitus.

Rabinovitch A.

Diabetes Metab Rev. 1998 Jun;14(2):129-51. Review.PMID: 9679667 [PubMed - indexed for MEDLINE]Related articles

Suppression of insulitis in non-obese diabetic (NOD) mice by oral insulin administration is associated with selective expression of interleukin-4 and -10, transforming growth factor-beta, and prostaglandin-E.

Hancock WW, Polanski M, Zhang J, Blogg N, Weiner HL.

Am J Pathol. 1995 Nov;147(5):1193-9.PMID: 7485382 [PubMed - indexed for MEDLINE]Related articlesFree article

IL-1beta and IFN-gamma induce the expression of diverse chemokines and IL-15 in human and rat pancreatic islet cells, and in islets from pre-diabetic NOD mice.

Cardozo AK, Proost P, Gysemans C, Chen MC, Mathieu C, Eizirik DL.

Diabetologia. 2003 Feb;46(2):255-66. Epub 2003 Feb 12.PMID: 12627325 [PubMed - indexed for MEDLINE]Related articles

Differential expression of CC chemokines and the CCR5 receptor in the pancreas is associated with progression to type I diabetes.

Cameron MJ, Arreaza GA, Grattan M, Meagher C, Sharif S, Burdick MD, Strieter RM, Cook DN, Delovitch TL.

J Immunol. 2000 Jul 15;165(2):1102-10.PMID: 10878389 [PubMed - indexed for MEDLINE]Related articlesFree article

alpha/beta-T cell receptor (TCR)+CD4-CD8- (NKT) thymocytes prevent insulin-dependent diabetes mellitus in nonobese diabetic (NOD)/Lt mice by the influence of interleukin (IL)-4 and/or IL-10.

Hammond KJ, Poulton LD, Palmisano LJ, Silveira PA, Godfrey DI, Baxter AG.

J Exp Med. 1998 Apr 6;187(7):1047-56.PMID: 9529321 [PubMed - indexed for MEDLINE]Related articlesFree article

A mechanism for IL-10-mediated diabetes in the nonobese diabetic (NOD) mouse: ICAM-1 deficiency blocks accelerated diabetes.

Balasa B, La Cava A, Van Gunst K, Mocnik L, Balakrishna D, Nguyen N, Tucker L, Sarvetnick N.

J Immunol. 2000 Dec 15;165(12):7330-7.PMID: 11120869 [PubMed - indexed for MEDLINE]Related articlesFree article

Interleukin 12 mRNA expression in islets correlates with beta-cell destruction in NOD mice.

Rabinovitch A, Suarez-Pinzon WL, Sorensen O.

J Autoimmun. 1996 Oct;9(5):645-51.PMID: 8933280 [PubMed - indexed for MEDLINE]Related articles

Paralytic autoimmune myositis develops in nonobese diabetic mice made Th1 cytokine-deficient by expression of an IFN-gamma receptor beta-chain transgene.

Serreze DV, Pierce MA, Post CM, Chapman HD, Savage H, Bronson RT, Rothman PB, Cox GA.

J Immunol. 2003 Mar 1;170(5):2742-9.PMID: 12594305 [PubMed - indexed for MEDLINE]Related articlesFree article

Pancreatic expression of interleukin-4 abrogates insulitis and autoimmune diabetes in nonobese diabetic (NOD) mice.

Mueller R, Krahl T, Sarvetnick N.

J Exp Med. 1996 Sep 1;184(3):1093-9.PMID: 9064326 [PubMed - indexed for MEDLINE]Related articlesFree article

A Reg family protein is overexpressed in islets from a patient with new-onset type 1 diabetes and acts as T-cell autoantigen in NOD mice.

Gurr W, Yavari R, Wen L, Shaw M, Mora C, Christa L, Sherwin RS.

Diabetes. 2002 Feb;51(2):339-46.PMID: 11812740 [PubMed - indexed for MEDLINE]Related articlesFree article

Administration of IL-4 prevents autoimmune diabetes but enhances pancreatic insulitis in NOD mice.

Tominaga Y, Nagata M, Yasuda H, Okamoto N, Arisawa K, Moriyama H, Miki M, Yokono K, Kasuga M.

Clin Immunol Immunopathol. 1998 Feb;86(2):209-18.PMID: 9473384 [PubMed - indexed for MEDLINE]Related articles