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    Results: 1 to 20 of 1092

    1.

    Antirheumatic drug response signatures in human chondrocytes: potential molecular targets to stimulate cartilage regeneration.

    Andreas K, Häupl T, Lübke C, Ringe J, Morawietz L, Wachtel A, Sittinger M, Kaps C.

    Arthritis Res Ther. 2009;11(1):R15. Epub 2009 Feb 3.

    PMID:
    19192274
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    2.

    Key regulatory molecules of cartilage destruction in rheumatoid arthritis: an in vitro study.

    Andreas K, Lübke C, Häupl T, Dehne T, Morawietz L, Ringe J, Kaps C, Sittinger M.

    Arthritis Res Ther. 2008;10(1):R9. Epub 2008 Jan 18.

    PMID:
    18205922
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    3.

    Kinesin-like protein CENP-E is upregulated in rheumatoid synovial fibroblasts.

    Kullmann F, Judex M, Ballhorn W, Jüsten HP, Wessinghage D, Welsh J, Yen TJ, Lang B, Hittle JC, McClelland M, Gay S, Schölmerich J, Müller-Ladner U.

    Arthritis Res. 1999;1(1):71-80. Epub 1999 Oct 26.

    PMID:
    11056662
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    4.

    The effects of 1 alpha,25-dihydroxyvitamin D(3) on matrix metalloproteinase and prostaglandin E(2) production by cells of the rheumatoid lesion.

    Tetlow LC, Woolley DE.

    Arthritis Res. 1999;1(1):63-70. Epub 1999 Oct 14.

    PMID:
    11056661
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    6.

    Mast cell activation and its relation to proinflammatory cytokine production in the rheumatoid lesion.

    Woolley DE, Tetlow LC.

    Arthritis Res. 2000;2(1):65-74.

    PMID:
    11219391
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    7.

    Gene expression profiling of rheumatoid arthritis synovial cells treated with antirheumatic drugs.

    Häupl T, Yahyawi M, Lübke C, Ringe J, Rohrlach T, Burmester GR, Sittinger M, Kaps C.

    J Biomol Screen. 2007 Apr;12(3):328-40. Epub 2007 Mar 22.

    PMID:
    17379860
    [PubMed - indexed for MEDLINE]
    8.

    Modulatory effects of inflammation and therapy on GDF-5 expression in rheumatoid arthritis synovium.

    Bramlage CP, Kaps C, Ungethüm U, Bramlage P, Koziolek M, Wessels J, Krenn V, Pruss A, Müller GA, Strutz F, Burmester GR, Häupl T.

    Scand J Rheumatol. 2008 Nov-Dec;37(6):401-9.

    PMID:
    18830904
    [PubMed - indexed for MEDLINE]
    9.

    In vitro model for the analysis of synovial fibroblast-mediated degradation of intact cartilage.

    Pretzel D, Pohlers D, Weinert S, Kinne RW.

    Arthritis Res Ther. 2009;11(1):R25. Epub 2009 Feb 18.

    PMID:
    19226472
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    10.

    Aurothiomalate inhibits COX-2 expression in chondrocytes and in human cartilage possibly through its effects on COX-2 mRNA stability.

    Nieminen R, Vuolteenaho K, Riutta A, Kankaanranta H, van der Kraan PM, Moilanen T, Moilanen E.

    Eur J Pharmacol. 2008 Jun 10;587(1-3):309-16. Epub 2008 Mar 29.

    PMID:
    18448096
    [PubMed - indexed for MEDLINE]
    11.

    The role of cytokines in osteoarthritis pathophysiology.

    Fernandes JC, Martel-Pelletier J, Pelletier JP.

    Biorheology. 2002;39(1-2):237-46. Review.

    PMID:
    12082286
    [PubMed - indexed for MEDLINE]
    12.

    Toll-like receptors and chondrocytes: the lipopolysaccharide-induced decrease in cartilage matrix synthesis is dependent on the presence of toll-like receptor 4 and antagonized by bone morphogenetic protein 7.

    Bobacz K, Sunk IG, Hofstaetter JG, Amoyo L, Toma CD, Akira S, Weichhart T, Saemann M, Smolen JS.

    Arthritis Rheum. 2007 Jun;56(6):1880-93.

    PMID:
    17530716
    [PubMed - indexed for MEDLINE]
    Free Article
    13.

    Matrix metalloproteinase 10 promotion of collagenolysis via procollagenase activation: implications for cartilage degradation in arthritis.

    Barksby HE, Milner JM, Patterson AM, Peake NJ, Hui W, Robson T, Lakey R, Middleton J, Cawston TE, Richards CD, Rowan AD.

    Arthritis Rheum. 2006 Oct;54(10):3244-53.

    PMID:
    17009259
    [PubMed - indexed for MEDLINE]
    Free Article
    14.

    Mediation of interleukin-1beta-induced transforming growth factor beta1 expression by activator protein 4 transcription factor in primary cultures of bovine articular chondrocytes: possible cooperation with activator protein 1.

    Andriamanalijaona R, Felisaz N, Kim SJ, King-Jones K, Lehmann M, Pujol JP, Boumediene K.

    Arthritis Rheum. 2003 Jun;48(6):1569-81.

    PMID:
    12794825
    [PubMed - indexed for MEDLINE]
    Free Article
    15.

    A 3D cartilage - inflammatory cell culture system for the modeling of human osteoarthritis.

    Sun L, Wang X, Kaplan DL.

    Biomaterials. 2011 Aug;32(24):5581-9. Epub 2011 May 12.

    PMID:
    21565399
    [PubMed - indexed for MEDLINE]
    16.

    Human rheumatoid arthritis tissue production of IL-17A drives matrix and cartilage degradation: synergy with tumour necrosis factor-alpha, Oncostatin M and response to biologic therapies.

    Moran EM, Mullan R, McCormick J, Connolly M, Sullivan O, Fitzgerald O, Bresnihan B, Veale DJ, Fearon U.

    Arthritis Res Ther. 2009;11(4):R113. Epub 2009 Jul 23.

    PMID:
    19627579
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    17.

    Expression of osteopontin messenger RNA and protein in rheumatoid arthritis: effects of osteopontin on the release of collagenase 1 from articular chondrocytes and synovial fibroblasts.

    Petrow PK, Hummel KM, Schedel J, Franz JK, Klein CL, Müller-Ladner U, Kriegsmann J, Chang PL, Prince CW, Gay RE, Gay S.

    Arthritis Rheum. 2000 Jul;43(7):1597-605.

    PMID:
    10902765
    [PubMed - indexed for MEDLINE]
    Free Article
    18.

    Egr-1 inhibits the expression of extracellular matrix genes in chondrocytes by TNFalpha-induced MEK/ERK signalling.

    Rockel JS, Bernier SM, Leask A.

    Arthritis Res Ther. 2009;11(1):R8. Epub 2009 Jan 14.

    PMID:
    19144181
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    19.

    Melanoma inhibitory activity, a biomarker related to chondrocyte anabolism, is reversibly suppressed by proinflammatory cytokines in rheumatoid arthritis.

    Vandooren B, Cantaert T, van Lierop MJ, Bos E, De Rycke L, Veys EM, De Keyser F, Bresnihan B, Luyten FP, Verdonk PC, Tak PP, Boots AH, Baeten D.

    Ann Rheum Dis. 2009 Jun;68(6):1044-50. Epub 2008 Jul 16.

    PMID:
    18633128
    [PubMed - indexed for MEDLINE]
    20.

    Gene expression profiling in the synovium identifies a predictive signature of absence of response to adalimumab therapy in rheumatoid arthritis.

    Badot V, Galant C, Nzeusseu Toukap A, Theate I, Maudoux AL, Van den Eynde BJ, Durez P, Houssiau FA, Lauwerys BR.

    Arthritis Res Ther. 2009;11(2):R57. Epub 2009 Apr 23.

    PMID:
    19389237
    [PubMed - indexed for MEDLINE]
    Free PMC Article

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