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    Results: 1 to 20 of 98

    1.

    Functional targets of the monogenic diabetes transcription factors HNF-1alpha and HNF-4alpha are highly conserved between mice and humans.

    Boj SF, Servitja JM, Martin D, Rios M, Talianidis I, Guigo R, Ferrer J.

    Diabetes. 2009 May;58(5):1245-53. Epub 2009 Feb 2.PMID: 19188435 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    Genetic evidence that HNF-1alpha-dependent transcriptional control of HNF-4alpha is essential for human pancreatic beta cell function.

    Hansen SK, Párrizas M, Jensen ML, Pruhova S, Ek J, Boj SF, Johansen A, Maestro MA, Rivera F, Eiberg H, Andel M, Lebl J, Pedersen O, Ferrer J, Hansen T.

    J Clin Invest. 2002 Sep;110(6):827-33.PMID: 12235114 [PubMed - indexed for MEDLINE]Related articlesFree article

    3.

    Mechanisms of mutual functional interactions between HNF-4alpha and HNF-1alpha revealed by mutations that cause maturity onset diabetes of the young.

    Rowley CW, Staloch LJ, Divine JK, McCaul SP, Simon TC.

    Am J Physiol Gastrointest Liver Physiol. 2006 Mar;290(3):G466-75. Epub 2005 Oct 13.PMID: 16223942 [PubMed - indexed for MEDLINE]Related articlesFree article

    4.

    Regulatory mechanisms controlling human hepatocyte nuclear factor 4alpha gene expression.

    Hatzis P, Talianidis I.

    Mol Cell Biol. 2001 Nov;21(21):7320-30.PMID: 11585914 [PubMed - indexed for MEDLINE]Related articlesFree article

    5.

    Expression of HNF-4alpha (MODY1), HNF-1beta (MODY5), and HNF-1alpha (MODY3) proteins in the developing mouse pancreas.

    Nammo T, Yamagata K, Tanaka T, Kodama T, Sladek FM, Fukui K, Katsube F, Sato Y, Miyagawa J, Shimomura I.

    Gene Expr Patterns. 2008 Jan;8(2):96-106. Epub 2007 Oct 9.PMID: 17996499 [PubMed - indexed for MEDLINE]Related articles

    6.

    Modulation of hepatocyte nuclear factor-4alpha function by the peroxisome-proliferator-activated receptor-gamma co-activator-1alpha in the acute-phase response.

    Wang Z, Burke PA.

    Biochem J. 2008 Oct 15;415(2):289-96.PMID: 18510493 [PubMed - indexed for MEDLINE]Related articlesFree article

    7.

    Profound defects in pancreatic beta-cell function in mice with combined heterozygous mutations in Pdx-1, Hnf-1alpha, and Hnf-3beta.

    Shih DQ, Heimesaat M, Kuwajima S, Stein R, Wright CV, Stoffel M.

    Proc Natl Acad Sci U S A. 2002 Mar 19;99(6):3818-23.PMID: 11904435 [PubMed - indexed for MEDLINE]Related articlesFree article

    8.

    Co-operative regulation of the transcription of human dihydrodiol dehydrogenase (DD)4/aldo-keto reductase (AKR)1C4 gene by hepatocyte nuclear factor (HNF)-4alpha/gamma and HNF-1alpha.

    Ozeki T, Takahashi Y, Kume T, Nakayama K, Yokoi T, Nunoya K, Hara A, Kamataki T.

    Biochem J. 2001 Apr 15;355(Pt 2):537-44.PMID: 11284743 [PubMed - indexed for MEDLINE]Related articlesFree article

    9.

    Regulation of apolipoprotein M gene expression by MODY3 gene hepatocyte nuclear factor-1alpha: haploinsufficiency is associated with reduced serum apolipoprotein M levels.

    Richter S, Shih DQ, Pearson ER, Wolfrum C, Fajans SS, Hattersley AT, Stoffel M.

    Diabetes. 2003 Dec;52(12):2989-95.PMID: 14633861 [PubMed - indexed for MEDLINE]Related articlesFree article

    10.

    Variants in the hepatocyte nuclear factor-1alpha and -4alpha genes in Finnish and Chinese subjects with late-onset type 2 diabetes.

    Rissanen J, Wang H, Miettinen R, Kärkkäinen P, Kekäläinen P, Mykkänen L, Kuusisto J, Karhapää P, Niskanen L, Uusitupa M, Laakso M.

    Diabetes Care. 2000 Oct;23(10):1533-8.PMID: 11023148 [PubMed - indexed for MEDLINE]Related articlesFree article

    11.

    Hepatocyte nuclear factor-4alpha is a central transactivator of the mouse Ntcp gene.

    Geier A, Martin IV, Dietrich CG, Balasubramaniyan N, Strauch S, Suchy FJ, Gartung C, Trautwein C, Ananthanarayanan M.

    Am J Physiol Gastrointest Liver Physiol. 2008 Aug;295(2):G226-33. Epub 2008 May 15.PMID: 18483185 [PubMed - indexed for MEDLINE]Related articlesFree article

    12.

    Hepatocyte nuclear factor-4alpha regulates the human apolipoprotein AV gene: identification of a novel response element and involvement in the control by peroxisome proliferator-activated receptor-gamma coactivator-1alpha, AMP-activated protein kinase, and mitogen-activated protein kinase pathway.

    Prieur X, Schaap FG, Coste H, Rodríguez JC.

    Mol Endocrinol. 2005 Dec;19(12):3107-25. Epub 2005 Jul 28.PMID: 16051671 [PubMed - indexed for MEDLINE]Related articlesFree article

    13.

    Loss of HNF-1alpha function in mice leads to abnormal expression of genes involved in pancreatic islet development and metabolism.

    Shih DQ, Screenan S, Munoz KN, Philipson L, Pontoglio M, Yaniv M, Polonsky KS, Stoffel M.

    Diabetes. 2001 Nov;50(11):2472-80.PMID: 11679424 [PubMed - indexed for MEDLINE]Related articlesFree article

    14.

    Role of liver-enriched transcription factors and nuclear receptors in regulating the human, mouse, and rat NTCP gene.

    Jung D, Hagenbuch B, Fried M, Meier PJ, Kullak-Ublick GA.

    Am J Physiol Gastrointest Liver Physiol. 2004 May;286(5):G752-61. Epub 2003 Dec 30.PMID: 14701722 [PubMed - indexed for MEDLINE]Related articlesFree article

    15.

    Comparative genomic analysis of the HNF-4alpha transcription factor gene.

    Bagwell AM, Bailly A, Mychaleckyj JC, Freedman BI, Bowden DW.

    Mol Genet Metab. 2004 Feb;81(2):112-21.PMID: 14741192 [PubMed - indexed for MEDLINE]Related articles

    16.

    Regulation of a transcription factor network required for differentiation and metabolism.

    Duncan SA, Navas MA, Dufort D, Rossant J, Stoffel M.

    Science. 1998 Jul 31;281(5377):692-5.PMID: 9685261 [PubMed - indexed for MEDLINE]Related articlesFree article

    17.

    A genetic switch in pancreatic beta-cells: implications for differentiation and haploinsufficiency.

    Ferrer J.

    Diabetes. 2002 Aug;51(8):2355-62. Review.PMID: 12145145 [PubMed - indexed for MEDLINE]Related articlesFree article

    18.

    beta-cell genes and diabetes: molecular and clinical characterization of mutations in transcription factors.

    Frayling TM, Evans JC, Bulman MP, Pearson E, Allen L, Owen K, Bingham C, Hannemann M, Shepherd M, Ellard S, Hattersley AT.

    Diabetes. 2001 Feb;50 Suppl 1:S94-100.PMID: 11272211 [PubMed - indexed for MEDLINE]Related articles

    19.

    Clinical characteristics, beta-cell function, HLA class II and mutations in MODY genes in non-paediatric subjects with Type 1 diabetes without pancreatic autoantibodies.

    Aguilera E, Casamitjana R, Ercilla G, Oriola J, Nicoletti F, Gomis R, Conget I.

    Diabet Med. 2005 Feb;22(2):137-43.PMID: 15660729 [PubMed - indexed for MEDLINE]Related articles

    20.

    Hepatocyte nuclear factor-4alpha promotes differentiation of intestinal epithelial cells in a coculture system.

    Lussier CR, Babeu JP, Auclair BA, Perreault N, Boudreau F.

    Am J Physiol Gastrointest Liver Physiol. 2008 Feb;294(2):G418-28. Epub 2007 Nov 21.PMID: 18032476 [PubMed - indexed for MEDLINE]Related articlesFree article

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