PubMed

Liver-specific loss of lipolysis-stimulated lipoprotein receptor triggers systemic hyperlipidemia in mice.

Narvekar P, Berriel Diaz M, Krones-Herzig A, Hardeland U, Strzoda D, Stöhr S, Frohme M, Herzig S.

Diabetes. 2009 May;58(5):1040-9. Epub 2009 Feb 2.PMID: 19188430 [PubMed - indexed for MEDLINE]Related articlesFree article

Lipolysis stimulated lipoprotein receptor: a novel molecular link between hyperlipidemia, weight gain, and atherosclerosis in mice.

Yen FT, Roitel O, Bonnard L, Notet V, Pratte D, Stenger C, Magueur E, Bihain BE.

J Biol Chem. 2008 Sep 12;283(37):25650-9. Epub 2008 Jul 21.PMID: 18644789 [PubMed - indexed for MEDLINE]Related articlesFree article

Molecular mechanisms of type III hyperlipoproteinemia: The contribution of the carboxy-terminal domain of ApoE can account for the dyslipidemia that is associated with the E2/E2 phenotype.

Kypreos KE, Li X, van Dijk KW, Havekes LM, Zannis VI.

Biochemistry. 2003 Aug 26;42(33):9841-53.PMID: 12924933 [PubMed - indexed for MEDLINE]Related articles

Decreased lipoprotein clearance is responsible for increased cholesterol in LDL receptor knockout mice with streptozotocin-induced diabetes.

Goldberg IJ, Hu Y, Noh HL, Wei J, Huggins LA, Rackmill MG, Hamai H, Reid BN, Blaner WS, Huang LS.

Diabetes. 2008 Jun;57(6):1674-82. Epub 2008 Mar 17.PMID: 18346984 [PubMed - indexed for MEDLINE]Related articlesFree article

Hypertriglyceridemia in lecithin-cholesterol acyltransferase-deficient mice is associated with hepatic overproduction of triglycerides, increased lipogenesis, and improved glucose tolerance.

Ng DS, Xie C, Maguire GF, Zhu X, Ugwu F, Lam E, Connelly PW.

J Biol Chem. 2004 Feb 27;279(9):7636-42. Epub 2003 Dec 10.PMID: 14668345 [PubMed - indexed for MEDLINE]Related articlesFree article

Overexpression and accumulation of apolipoprotein E as a cause of hypertriglyceridemia.

Huang Y, Liu XQ, Rall SC Jr, Taylor JM, von Eckardstein A, Assmann G, Mahley RW.

J Biol Chem. 1998 Oct 9;273(41):26388-93.PMID: 9756870 [PubMed - indexed for MEDLINE]Related articlesFree article

Generation and characterization of two novel mouse models exhibiting the phenotypes of the metabolic syndrome: Apob48-/-Lepob/ob mice devoid of ApoE or Ldlr.

Lloyd DJ, McCormick J, Helmering J, Kim KW, Wang M, Fordstrom P, Kaufman SA, Lindberg RA, Véniant MM.

Am J Physiol Endocrinol Metab. 2008 Mar;294(3):E496-505. Epub 2007 Dec 26.PMID: 18160459 [PubMed - indexed for MEDLINE]Related articlesFree article

LDL receptor but not apolipoprotein E deficiency increases diet-induced obesity and diabetes in mice.

Schreyer SA, Vick C, Lystig TC, Mystkowski P, LeBoeuf RC.

Am J Physiol Endocrinol Metab. 2002 Jan;282(1):E207-14.PMID: 11739102 [PubMed - indexed for MEDLINE]Related articlesFree article

Expression of human apolipoprotein A-II in apolipoprotein E-deficient mice induces features of familial combined hyperlipidemia.

Escolà-Gil JC, Julve J, Marzal-Casacuberta A, Ordóñez-Llanos J, González-Sastre F, Blanco-Vaca F.

J Lipid Res. 2000 Aug;41(8):1328-38.PMID: 10946021 [PubMed - indexed for MEDLINE]Related articlesFree article

Cafestol increases serum cholesterol levels in apolipoprotein E*3-Leiden transgenic mice by suppression of bile acid synthesis.

Post SM, de Roos B, Vermeulen M, Afman L, Jong MC, Dahlmans VE, Havekes LM, Stellaard F, Katan MB, Princen HM.

Arterioscler Thromb Vasc Biol. 2000 Jun;20(6):1551-6.PMID: 10845871 [PubMed - indexed for MEDLINE]Related articlesFree article

Apolipoprotein E2 reduces the low density lipoprotein level in transgenic mice by impairing lipoprotein lipase-mediated lipolysis of triglyceride-rich lipoproteins.

Huang Y, Liu XQ, Rall SC Jr, Mahley RW.

J Biol Chem. 1998 Jul 10;273(28):17483-90.PMID: 9651338 [PubMed - indexed for MEDLINE]Related articlesFree article

Mice deficient in apolipoprotein E but not LDL receptors are resistant to accelerated atherosclerosis associated with obesity.

Schreyer SA, Lystig TC, Vick CM, LeBoeuf RC.

Atherosclerosis. 2003 Nov;171(1):49-55.PMID: 14642405 [PubMed - indexed for MEDLINE]Related articles

Overexpression of apolipoprotein E3 in transgenic rabbits causes combined hyperlipidemia by stimulating hepatic VLDL production and impairing VLDL lipolysis.

Huang Y, Ji ZS, Brecht WJ, Rall SC Jr, Taylor JM, Mahley RW.

Arterioscler Thromb Vasc Biol. 1999 Dec;19(12):2952-9.PMID: 10591675 [PubMed - indexed for MEDLINE]Related articlesFree article

Apolipoprotein E participates in the regulation of very low density lipoprotein-triglyceride secretion by the liver.

Mensenkamp AR, Jong MC, van Goor H, van Luyn MJ, Bloks V, Havinga R, Voshol PJ, Hofker MH, van Dijk KW, Havekes LM, Kuipers F.

J Biol Chem. 1999 Dec 10;274(50):35711-8.PMID: 10585451 [PubMed - indexed for MEDLINE]Related articlesFree article

The db/db mouse, a model for diabetic dyslipidemia: molecular characterization and effects of Western diet feeding.

Kobayashi K, Forte TM, Taniguchi S, Ishida BY, Oka K, Chan L.

Metabolism. 2000 Jan;49(1):22-31.PMID: 10647060 [PubMed - indexed for MEDLINE]Related articles

Carbenoxolone treatment attenuates symptoms of metabolic syndrome and atherogenesis in obese, hyperlipidemic mice.

Nuotio-Antar AM, Hachey DL, Hasty AH.

Am J Physiol Endocrinol Metab. 2007 Dec;293(6):E1517-28. Epub 2007 Sep 18. Erratum in: Am J Physiol Endocrinol Metab. 2008 May;294(5):E993. PMID: 17878220 [PubMed - indexed for MEDLINE]Related articlesFree article

Resistance of chylomicron and VLDL remnants to post-heparin lipolysis in ApoE-deficient mice: the role of apoE in lipoprotein lipase-mediated lipolysis in vivo and in vitro.

Zsigmond E, Fuke Y, Li L, Kobayashi K, Chan L.

J Lipid Res. 1998 Sep;39(9):1852-61.PMID: 9741698 [PubMed - indexed for MEDLINE]Related articlesFree article

Inhibitory effects of specific apolipoprotein C-III isoforms on the binding of triglyceride-rich lipoproteins to the lipolysis-stimulated receptor.

Mann CJ, Troussard AA, Yen FT, Hannouche N, Najib J, Fruchart JC, Lotteau V, André P, Bihain BE.

J Biol Chem. 1997 Dec 12;272(50):31348-54.PMID: 9395464 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of vitamin E on oxidative stress and atherosclerosis in an obese hyperlipidemic mouse model.

Hasty AH, Gruen ML, Terry ES, Surmi BK, Atkinson RD, Gao L, Morrow JD.

J Nutr Biochem. 2007 Feb;18(2):127-33. Epub 2006 Jun 16.PMID: 16781857 [PubMed - indexed for MEDLINE]Related articles

Hyperlipidemia of ApoE2(Arg(158)-Cys) and ApoE3-Leiden transgenic mice is modulated predominantly by LDL receptor expression.

van Dijk KW, van Vlijmen BJ, de Winther MP, van 't Hof B, van der Zee A, van der Boom H, Havekes LM, Hofker MH.

Arterioscler Thromb Vasc Biol. 1999 Dec;19(12):2945-51.PMID: 10591674 [PubMed - indexed for MEDLINE]Related articlesFree article