PubMed

Protective effect of perindopril on diabetic retinopathy is associated with decreased vascular endothelial growth factor-to-pigment epithelium-derived factor ratio: involvement of a mitochondria-reactive oxygen species pathway.

Zheng Z, Chen H, Ke G, Fan Y, Zou H, Sun X, Gu Q, Xu X, Ho PC.

Diabetes. 2009 Apr;58(4):954-64. Epub 2009 Feb 2.PMID: 19188429 [PubMed - indexed for MEDLINE]Related articlesFree article

Pigment epithelium-derived factor inhibits advanced glycation end product-induced retinal vascular hyperpermeability by blocking reactive oxygen species-mediated vascular endothelial growth factor expression.

Yamagishi S, Nakamura K, Matsui T, Inagaki Y, Takenaka K, Jinnouchi Y, Yoshida Y, Matsuura T, Narama I, Motomiya Y, Takeuchi M, Inoue H, Yoshimura A, Bucala R, Imaizumi T.

J Biol Chem. 2006 Jul 21;281(29):20213-20. Epub 2006 May 17.PMID: 16707486 [PubMed - indexed for MEDLINE]Related articlesFree article

PEDF inhibits JAK2/STAT3-mediated VEGF upregulation under high glucose condition through a mitochondrial ROS pathway in vitro.

Zheng Z, Chen H, Zhao H, Liu K, Luo D, Chen Y, Chen Y, Yang X, Gu Q, Xu X.

Invest Ophthalmol Vis Sci. 2009 Aug 20. [Epub ahead of print]PMID: 19696171 [PubMed - as supplied by publisher]Related articles

Pigment epithelium-derived factor downregulates vascular endothelial growth factor (VEGF) expression and inhibits VEGF-VEGF receptor 2 binding in diabetic retinopathy.

Zhang SX, Wang JJ, Gao G, Parke K, Ma JX.

J Mol Endocrinol. 2006 Aug;37(1):1-12.PMID: 16901919 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of angiotensin-converting enzyme inhibitors and beta-adrenergic blockers on retinal vascular endothelial growth factor expression in rat diabetic retinopathy.

Zheng Z, Chen H, Xu X, Li C, Gu Q.

Exp Eye Res. 2007 Apr;84(4):745-52. Epub 2006 Dec 31.PMID: 17303121 [PubMed - indexed for MEDLINE]Related articles

Angiotensin converting enzyme inhibition reduces retinal overexpression of vascular endothelial growth factor and hyperpermeability in experimental diabetes.

Gilbert RE, Kelly DJ, Cox AJ, Wilkinson-Berka JL, Rumble JR, Osicka T, Panagiotopoulos S, Lee V, Hendrich EC, Jerums G, Cooper ME.

Diabetologia. 2000 Nov;43(11):1360-7.PMID: 11126403 [PubMed - indexed for MEDLINE]Related articles

Pigment epithelium-derived factor (PEDF) is an endogenous antiinflammatory factor.

Zhang SX, Wang JJ, Gao G, Shao C, Mott R, Ma JX.

FASEB J. 2006 Feb;20(2):323-5. Epub 2005 Dec 20.PMID: 16368716 [PubMed - indexed for MEDLINE]Related articlesFree article

Anti-inflammatory effects of pigment epithelium-derived factor in diabetic nephropathy.

Wang JJ, Zhang SX, Mott R, Chen Y, Knapp RR, Cao W, Ma JX.

Am J Physiol Renal Physiol. 2008 May;294(5):F1166-73. Epub 2008 Mar 5.PMID: 18322021 [PubMed - indexed for MEDLINE]Related articlesFree article

Reduction of experimental diabetic vascular leakage by delivery of angiostatin with a recombinant adeno-associated virus vector.

Shyong MP, Lee FL, Kuo PC, Wu AC, Cheng HC, Chen SL, Tung TH, Tsao YP.

Mol Vis. 2007 Jan 31;13:133-41.PMID: 17293777 [PubMed - indexed for MEDLINE]Related articlesFree article

Effect of over-expression of pigment epithelium derived factor (PEDF) on developing retinal vasculature in the mouse.

Wong WT, Rex TS, Auricchio A, Maguire AM, Chung D, Tang W, Bennett J.

Mol Vis. 2004 Nov 8;10:837-44.PMID: 15547489 [PubMed - indexed for MEDLINE]Related articlesFree article

Expression of pigment epithelium-derived factor (PEDF) and vascular endothelial growth factor (VEGF) in sickle cell retina and choroid.

Kim SY, Mocanu C, Mcleod DS, Bhutto IA, Merges C, Eid M, Tong P, Lutty GA.

Exp Eye Res. 2003 Oct;77(4):433-45.PMID: 12957143 [PubMed - indexed for MEDLINE]Related articles

Molecular mechanism of limbs' postischemic revascularization improved by perindopril in diabetic rats.

Gao L, Yu DM.

Chin Med J (Engl). 2008 Nov 5;121(21):2129-33.PMID: 19080171 [PubMed - indexed for MEDLINE]Related articlesFree article

Salutary effect of pigment epithelium-derived factor in diabetic nephropathy: evidence for antifibrogenic activities.

Wang JJ, Zhang SX, Mott R, Knapp RR, Cao W, Lau K, Ma JX.

Diabetes. 2006 Jun;55(6):1678-85.PMID: 16731830 [PubMed - indexed for MEDLINE]Related articlesFree article

Pigment epithelium-derived factor suppresses ischemia-induced retinal neovascularization and VEGF-induced migration and growth.

Duh EJ, Yang HS, Suzuma I, Miyagi M, Youngman E, Mori K, Katai M, Yan L, Suzuma K, West K, Davarya S, Tong P, Gehlbach P, Pearlman J, Crabb JW, Aiello LP, Campochiaro PA, Zack DJ.

Invest Ophthalmol Vis Sci. 2002 Mar;43(3):821-9.PMID: 11867604 [PubMed - indexed for MEDLINE]Related articlesFree article

Expression modification of uncoupling proteins and MnSOD in retinal endothelial cells and pericytes induced by high glucose: the role of reactive oxygen species in diabetic retinopathy.

Cui Y, Xu X, Bi H, Zhu Q, Wu J, Xia X, Qiushi Ren, Ho PC.

Exp Eye Res. 2006 Oct;83(4):807-16. Epub 2006 Jun 5.PMID: 16750827 [PubMed - indexed for MEDLINE]Related articles

Pigment epithelium-derived factor inhibits leptin-induced angiogenesis by suppressing vascular endothelial growth factor gene expression through anti-oxidative properties.

Yamagishi S, Amano S, Inagaki Y, Okamoto T, Takeuchi M, Inoue H.

Microvasc Res. 2003 May;65(3):186-90.PMID: 12711260 [PubMed - indexed for MEDLINE]Related articles

Pigment-epithelium-derived factor suppresses expression of receptor for advanced glycation end products in the eye of diabetic rats.

Yamagishi S, Matsui T, Nakamura K, Yoshida T, Takeuchi M, Inoue H, Yoshida Y, Imaizumi T.

Ophthalmic Res. 2007;39(2):92-7. Epub 2007 Feb 2.PMID: 17284935 [PubMed - indexed for MEDLINE]Related articles

Anti-inflammatory and antioxidant effects of SERPINA3K in the retina.

Zhang B, Hu Y, Ma JX.

Invest Ophthalmol Vis Sci. 2009 Aug;50(8):3943-52. Epub 2009 Mar 25.PMID: 19324842 [PubMed - indexed for MEDLINE]Related articles

[Downregulation of the pigment epithelium derived factor by hypoxia and elevated glucose concentration in cultured human retinal pigment epithelial cells]

Yao Y, Guan M, Zhao XQ, Huang YF.

Zhonghua Yi Xue Za Zhi. 2003 Nov 25;83(22):1989-92. Chinese. PMID: 14703436 [PubMed - indexed for MEDLINE]Related articles

Leukostasis and pigment epithelium-derived factor in rat models of diabetic retinopathy.

Matsuoka M, Ogata N, Minamino K, Matsumura M.

Mol Vis. 2007 Jun 29;13:1058-65.PMID: 17653050 [PubMed - indexed for MEDLINE]Related articlesFree article