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Specific local cardiovascular changes of Nepsilon-(carboxymethyl)lysine, vascular endothelial growth factor, and Smad2 in the developing embryos coincide with maternal diabetes-induced congenital heart defects.

Roest PA, Molin DG, Schalkwijk CG, van Iperen L, Wentzel P, Eriksson UJ, Gittenberger-de Groot AC.

Diabetes. 2009 May;58(5):1222-8. Epub 2009 Feb 2.PMID: 19188426 [PubMed - indexed for MEDLINE]Related articlesFree article

Increased levels of vascular endothelial growth factor and advanced glycation end products in aqueous humor of patients with diabetic retinopathy.

Endo M, Yanagisawa K, Tsuchida K, Okamoto T, Matsushita T, Higuchi M, Matsuda A, Takeuchi M, Makita Z, Koike T.

Horm Metab Res. 2001 May;33(5):317-22.PMID: 11440280 [PubMed - indexed for MEDLINE]Related articles

The relationship between accumulation of advanced glycation end products and expression of vascular endothelial growth factor in human diabetic retinas.

Murata T, Nagai R, Ishibashi T, Inomuta H, Ikeda K, Horiuchi S.

Diabetologia. 1997 Jul;40(7):764-9.PMID: 9243096 [PubMed - indexed for MEDLINE]Related articles

Role of the vascular endothelial growth factor isoforms in retinal angiogenesis and DiGeorge syndrome.

Stalmans I.

Verh K Acad Geneeskd Belg. 2005;67(4):229-76. Review.PMID: 16334858 [PubMed - indexed for MEDLINE]Related articles

Diabetic retinopathy risk correlates with intracellular concentrations of the glycoxidation product Nepsilon-(carboxymethyl) lysine independently of glycohaemoglobin concentrations.

Hammes HP, Brownlee M, Lin J, Schleicher E, Bretzel RG.

Diabetologia. 1999 May;42(5):603-7.PMID: 10333054 [PubMed - indexed for MEDLINE]Related articles

Increased Nepsilon-(carboxymethyl)-lysine levels in cerebral blood vessels of diabetic patients and in a (streptozotocin-treated) rat model of diabetes mellitus.

van Deutekom AW, Niessen HW, Schalkwijk CG, Heine RJ, Simsek S.

Eur J Endocrinol. 2008 May;158(5):655-60.PMID: 18426823 [PubMed - indexed for MEDLINE]Related articlesFree article

Reactive oxygen species accelerate production of vascular endothelial growth factor by advanced glycation end products in RAW264.7 mouse macrophages.

Urata Y, Yamaguchi M, Higashiyama Y, Ihara Y, Goto S, Kuwano M, Horiuchi S, Sumikawa K, Kondo T.

Free Radic Biol Med. 2002 Apr 15;32(8):688-701.PMID: 11937295 [PubMed - indexed for MEDLINE]Related articles

Increased accumulation of the glycoxidation product Nepsilon-(carboxymethyl)lysine in hearts of diabetic patients: generation and characterisation of a monoclonal anti-CML antibody.

Schalkwijk CG, Baidoshvili A, Stehouwer CD, van Hinsbergh VW, Niessen HW.

Biochim Biophys Acta. 2004 Mar 22;1636(2-3):82-9.PMID: 15164755 [PubMed - indexed for MEDLINE]Related articles

Overproduction of N(epsilon)-(carboxymethyl)lysine-induced neovascularization in cultured choroidal explant of streptozotocin-diabetic rat.

Kobayashi S, Suzuki M, Tsuneki H, Nagai R, Horiuchi S, Hagino N.

Biol Pharm Bull. 2004 Oct;27(10):1565-71.PMID: 15467196 [PubMed - indexed for MEDLINE]Related articlesFree article

Mechanical ventilation during experimental sepsis increases deposition of advanced glycation end products and myocardial inflammation.

Kneyber MC, Gazendam RP, Niessen HW, Kuiper JW, Dos Santos CC, Slutsky AS, Plötz FB.

Crit Care. 2009;13(3):R87. Epub 2009 Jun 9.PMID: 19508707 [PubMed - indexed for MEDLINE]Related articlesFree article

Overproduction of N(epsilon)-(carboxymethyl)lysine-induced neovascularization in cultured choroidal explant of aged rat.

Kobayashi S, Nomura M, Nishioka T, Kikuchi M, Ishihara A, Nagai R, Hagino N.

Biol Pharm Bull. 2007 Jan;30(1):133-8.PMID: 17202673 [PubMed - indexed for MEDLINE]Related articlesFree article

Reduction of retinal albumin leakage by the antioxidant calcium dobesilate in streptozotocin-diabetic rats.

Rota R, Chiavaroli C, Garay RP, Hannaert P.

Eur J Pharmacol. 2004 Jul 14;495(2-3):217-24.PMID: 15249173 [PubMed - indexed for MEDLINE]Related articles

Immunohistochemical colocalization of glycoxidation products and lipid peroxidation products in diabetic renal glomerular lesions. Implication for glycoxidative stress in the pathogenesis of diabetic nephropathy.

Horie K, Miyata T, Maeda K, Miyata S, Sugiyama S, Sakai H, van Ypersole de Strihou C, Monnier VM, Witztum JL, Kurokawa K.

J Clin Invest. 1997 Dec 15;100(12):2995-3004.PMID: 9399945 [PubMed - indexed for MEDLINE]Related articlesFree article

Angiotensin II receptor blocker inhibits abnormal accumulation of advanced glycation end products and retinal damage in a rat model of type 2 diabetes.

Sugiyama T, Okuno T, Fukuhara M, Oku H, Ikeda T, Obayashi H, Ohta M, Fukui M, Hasegawa G, Nakamura N.

Exp Eye Res. 2007 Sep;85(3):406-12. Epub 2007 Jun 19.PMID: 17678894 [PubMed - indexed for MEDLINE]Related articles

An inhibitor of advanced glycation end product formation reduces N epsilon-(carboxymethyl)lysine accumulation in glomeruli of diabetic rats.

Nakamura S, Tachikawa T, Tobita K, Aoyama I, Takayama F, Enomoto A, Niwa T.

Am J Kidney Dis. 2003 Mar;41(3 Suppl 1):S68-71.PMID: 12612956 [PubMed - indexed for MEDLINE]Related articles

Cardiac malformations are associated with altered expression of vascular endothelial growth factor and endothelial nitric oxide synthase genes in embryos of diabetic mice.

Kumar SD, Yong SK, Dheen ST, Bay BH, Tay SS.

Exp Biol Med (Maywood). 2008 Nov;233(11):1421-32. Epub 2008 Sep 29.PMID: 18824721 [PubMed - indexed for MEDLINE]Related articlesFree article

The levels of vascular endothelial growth factor-A and placental growth factor-2 in embryopathy associated with experimental diabetic gestation.

Salim MD, Al-Matubsi HY, El-Sharaky AS, Kamel MA, Oriquat GA, Helmy MH, El-Bassiouni EA.

Growth Factors. 2009 Feb;27(1):32-9.PMID: 19048427 [PubMed - indexed for MEDLINE]Related articles

Serum levels of advanced glycation end products are increased in patients with type 2 diabetes and coronary heart disease.

Kilhovd BK, Berg TJ, Birkeland KI, Thorsby P, Hanssen KF.

Diabetes Care. 1999 Sep;22(9):1543-8.PMID: 10480523 [PubMed - indexed for MEDLINE]Related articlesFree article

Circulating soluble receptor for advanced glycation end products is inversely associated with glycemic control and S100A12 protein.

Basta G, Sironi AM, Lazzerini G, Del Turco S, Buzzigoli E, Casolaro A, Natali A, Ferrannini E, Gastaldelli A.

J Clin Endocrinol Metab. 2006 Nov;91(11):4628-34. Epub 2006 Aug 22.PMID: 16926247 [PubMed - indexed for MEDLINE]Related articlesFree article

Advanced glycation end products increase, through a protein kinase C-dependent pathway, vascular endothelial growth factor expression in retinal endothelial cells. Inhibitory effect of gliclazide.

Mamputu JC, Renier G.

J Diabetes Complications. 2002 Jul-Aug;16(4):284-93.PMID: 12126787 [PubMed - indexed for MEDLINE]Related articles