PubMed

Munc18c depletion selectively impairs the sustained phase of insulin release.

Oh E, Thurmond DC.

Diabetes. 2009 May;58(5):1165-74. Epub 2009 Feb 2.PMID: 19188424 [PubMed - indexed for MEDLINE]Related articlesFree article

Doc2beta is a novel Munc18c-interacting partner and positive effector of syntaxin 4-mediated exocytosis.

Ke B, Oh E, Thurmond DC.

J Biol Chem. 2007 Jul 27;282(30):21786-97. Epub 2007 Jun 4.PMID: 17548353 [PubMed - indexed for MEDLINE]Related articlesFree article

The stimulus-induced tyrosine phosphorylation of Munc18c facilitates vesicle exocytosis.

Oh E, Thurmond DC.

J Biol Chem. 2006 Jun 30;281(26):17624-34. Epub 2006 Apr 25.PMID: 16638745 [PubMed - indexed for MEDLINE]Related articlesFree article

Syntaxin 4 facilitates biphasic glucose-stimulated insulin secretion from pancreatic beta-cells.

Spurlin BA, Thurmond DC.

Mol Endocrinol. 2006 Jan;20(1):183-93. Epub 2005 Aug 11.PMID: 16099818 [PubMed - indexed for MEDLINE]Related articlesFree article

Transduction of MIN6 beta cells with TAT-syntaxin SNARE motif inhibits insulin exocytosis in biphasic insulin release in a distinct mechanism analyzed by evanescent wave microscopy.

Ohara-Imaizumi M, Nakamichi Y, Nishiwaki C, Nagamatsu S.

J Biol Chem. 2002 Dec 27;277(52):50805-11. Epub 2002 Oct 21.PMID: 12393909 [PubMed - indexed for MEDLINE]Related articlesFree article

Insulin-triggered repositioning of munc18c on syntaxin-4 in GLUT4 signalling.

Smithers NP, Hodgkinson CP, Cuttle M, Sale GJ.

Biochem J. 2008 Mar 1;410(2):255-60.PMID: 17956227 [PubMed - indexed for MEDLINE]Related articlesFree article

The tyrosine phosphorylation of Munc18c induces a switch in binding specificity from syntaxin 4 to Doc2beta.

Jewell JL, Oh E, Bennett SM, Meroueh SO, Thurmond DC.

J Biol Chem. 2008 Aug 1;283(31):21734-46. Epub 2008 Jun 9.PMID: 18541526 [PubMed - indexed for MEDLINE]Related articlesFree article

WNK1 is a novel regulator of Munc18c-syntaxin 4 complex formation in soluble NSF attachment protein receptor (SNARE)-mediated vesicle exocytosis.

Oh E, Heise CJ, English JM, Cobb MH, Thurmond DC.

J Biol Chem. 2007 Nov 9;282(45):32613-22. Epub 2007 Sep 11.PMID: 17848561 [PubMed - indexed for MEDLINE]Related articlesFree article

Glucose-stimulated Cdc42 signaling is essential for the second phase of insulin secretion.

Wang Z, Oh E, Thurmond DC.

J Biol Chem. 2007 Mar 30;282(13):9536-46. Epub 2007 Feb 8.PMID: 17289663 [PubMed - indexed for MEDLINE]Related articlesFree article

Negative regulation of syntaxin4/SNAP-23/VAMP2-mediated membrane fusion by Munc18c in vitro.

Brandie FM, Aran V, Verma A, McNew JA, Bryant NJ, Gould GW.

PLoS One. 2008;3(12):e4074. Epub 2008 Dec 31.PMID: 19116655 [PubMed - indexed for MEDLINE]Related articlesFree article

A role for Sec1/Munc18 proteins in platelet exocytosis.

Schraw TD, Lemons PP, Dean WL, Whiteheart SW.

Biochem J. 2003 Aug 15;374(Pt 1):207-17.PMID: 12773094 [PubMed - indexed for MEDLINE]Related articlesFree article

A direct interaction between Cdc42 and vesicle-associated membrane protein 2 regulates SNARE-dependent insulin exocytosis.

Nevins AK, Thurmond DC.

J Biol Chem. 2005 Jan 21;280(3):1944-52. Epub 2004 Nov 9.PMID: 15537656 [PubMed - indexed for MEDLINE]Related articlesFree article

Munc18-syntaxin complexes and exocytosis in human platelets.

Houng A, Polgar J, Reed GL.

J Biol Chem. 2003 May 30;278(22):19627-33. Epub 2003 Mar 20.PMID: 12649283 [PubMed - indexed for MEDLINE]Related articlesFree article

Munc 18-1 and granuphilin collaborate during insulin granule exocytosis.

Tomas A, Meda P, Regazzi R, Pessin JE, Halban PA.

Traffic. 2008 May;9(5):813-32. Epub 2008 Jan 19.PMID: 18208509 [PubMed - indexed for MEDLINE]Related articles

Site of docking and fusion of insulin secretory granules in live MIN6 beta cells analyzed by TAT-conjugated anti-syntaxin 1 antibody and total internal reflection fluorescence microscopy.

Ohara-Imaizumi M, Nishiwaki C, Kikuta T, Kumakura K, Nakamichi Y, Nagamatsu S.

J Biol Chem. 2004 Feb 27;279(9):8403-8. Epub 2003 Dec 15.PMID: 14676208 [PubMed - indexed for MEDLINE]Related articlesFree article

Munc18c heterozygous knockout mice display increased susceptibility for severe glucose intolerance.

Oh E, Spurlin BA, Pessin JE, Thurmond DC.

Diabetes. 2005 Mar;54(3):638-47.PMID: 15734838 [PubMed - indexed for MEDLINE]Related articlesFree article

Munc18c interaction with syntaxin 4 monomers and SNARE complex intermediates in GLUT4 vesicle trafficking.

D'Andrea-Merrins M, Chang L, Lam AD, Ernst SA, Stuenkel EL.

J Biol Chem. 2007 Jun 1;282(22):16553-66. Epub 2007 Apr 5.PMID: 17412693 [PubMed - indexed for MEDLINE]Related articlesFree article

Characterization of SNARE protein expression in beta cell lines and pancreatic islets.

Wheeler MB, Sheu L, Ghai M, Bouquillon A, Grondin G, Weller U, Beaudoin AR, Bennett MK, Trimble WS, Gaisano HY.

Endocrinology. 1996 Apr;137(4):1340-8.PMID: 8625909 [PubMed - indexed for MEDLINE]Related articles

TCF7L2 regulates late events in insulin secretion from pancreatic islet beta-cells.

da Silva Xavier G, Loder MK, McDonald A, Tarasov AI, Carzaniga R, Kronenberger K, Barg S, Rutter GA.

Diabetes. 2009 Apr;58(4):894-905. Epub 2009 Jan 23.PMID: 19168596 [PubMed - indexed for MEDLINE]Related articlesFree article

Regulation of insulin exocytosis by Munc13-1.

Sheu L, Pasyk EA, Ji J, Huang X, Gao X, Varoqueaux F, Brose N, Gaisano HY.

J Biol Chem. 2003 Jul 25;278(30):27556-63. Epub 2003 May 13.PMID: 12871971 [PubMed - indexed for MEDLINE]Related articlesFree article