PubMed

Imatinib mesylate reduces endoplasmic reticulum stress and induces remission of diabetes in db/db mice.

Han MS, Chung KW, Cheon HG, Rhee SD, Yoon CH, Lee MK, Kim KW, Lee MS.

Diabetes. 2009 Feb;58(2):329-36.PMID: 19171749 [PubMed - indexed for MEDLINE]Related articlesFree article

Cytokine-induced beta-cell death is independent of endoplasmic reticulum stress signaling.

Akerfeldt MC, Howes J, Chan JY, Stevens VA, Boubenna N, McGuire HM, King C, Biden TJ, Laybutt DR.

Diabetes. 2008 Nov;57(11):3034-44. Epub 2008 Jun 30.PMID: 18591394 [PubMed - indexed for MEDLINE]Related articlesFree article

Therapeutic potential of peroxisome proliferators--activated receptor-alpha/gamma dual agonist with alleviation of endoplasmic reticulum stress for the treatment of diabetes.

Han KL, Choi JS, Lee JY, Song J, Joe MK, Jung MH, Hwang JK.

Diabetes. 2008 Mar;57(3):737-45. Epub 2007 Dec 7.PMID: 18065517 [PubMed - indexed for MEDLINE]Related articlesFree article

Diazoxide-induced beta-cell rest reduces endoplasmic reticulum stress in lipotoxic beta-cells.

Sargsyan E, Ortsäter H, Thorn K, Bergsten P.

J Endocrinol. 2008 Oct;199(1):41-50. Epub 2008 Jul 21.PMID: 18644846 [PubMed - indexed for MEDLINE]Related articlesFree article

Endoplasmic reticulum stress contributes to beta cell apoptosis in type 2 diabetes.

Laybutt DR, Preston AM, Akerfeldt MC, Kench JG, Busch AK, Biankin AV, Biden TJ.

Diabetologia. 2007 Apr;50(4):752-63. Epub 2007 Feb 1.PMID: 17268797 [PubMed - indexed for MEDLINE]Related articles

Role of oxidative stress, endoplasmic reticulum stress, and c-Jun N-terminal kinase in pancreatic beta-cell dysfunction and insulin resistance.

Kaneto H, Nakatani Y, Kawamori D, Miyatsuka T, Matsuoka TA, Matsuhisa M, Yamasaki Y.

Int J Biochem Cell Biol. 2006;38(5-6):782-93. Review.PMID: 16607699 [PubMed - indexed for MEDLINE]Related articles

Chromium alleviates glucose intolerance, insulin resistance, and hepatic ER stress in obese mice.

Sreejayan N, Dong F, Kandadi MR, Yang X, Ren J.

Obesity (Silver Spring). 2008 Jun;16(6):1331-7. Epub 2008 Apr 3.PMID: 18388893 [PubMed - indexed for MEDLINE]Related articles

CCAAT/enhancing binding protein beta deletion in mice attenuates inflammation, endoplasmic reticulum stress, and lipid accumulation in diet-induced nonalcoholic steatohepatitis.

Rahman SM, Schroeder-Gloeckler JM, Janssen RC, Jiang H, Qadri I, Maclean KN, Friedman JE.

Hepatology. 2007 May;45(5):1108-17.PMID: 17464987 [PubMed - indexed for MEDLINE]Related articles

Inhibition of Foxo1 protects pancreatic islet beta-cells against fatty acid and endoplasmic reticulum stress-induced apoptosis.

Martinez SC, Tanabe K, Cras-Méneur C, Abumrad NA, Bernal-Mizrachi E, Permutt MA.

Diabetes. 2008 Apr;57(4):846-59. Epub 2008 Jan 3.PMID: 18174526 [PubMed - indexed for MEDLINE]Related articlesFree article

High expression rates of human islet amyloid polypeptide induce endoplasmic reticulum stress mediated beta-cell apoptosis, a characteristic of humans with type 2 but not type 1 diabetes.

Huang CJ, Lin CY, Haataja L, Gurlo T, Butler AE, Rizza RA, Butler PC.

Diabetes. 2007 Aug;56(8):2016-27. Epub 2007 May 2.PMID: 17475933 [PubMed - indexed for MEDLINE]Related articlesFree article

Effect of pioglitazone treatment on endoplasmic reticulum stress response in human adipose and in palmitate-induced stress in human liver and adipose cell lines.

Das SK, Chu WS, Mondal AK, Sharma NK, Kern PA, Rasouli N, Elbein SC.

Am J Physiol Endocrinol Metab. 2008 Aug;295(2):E393-400. Epub 2008 Jun 10.PMID: 18544642 [PubMed - indexed for MEDLINE]Related articlesFree article

Selective inhibition of eukaryotic translation initiation factor 2 alpha dephosphorylation potentiates fatty acid-induced endoplasmic reticulum stress and causes pancreatic beta-cell dysfunction and apoptosis.

Cnop M, Ladriere L, Hekerman P, Ortis F, Cardozo AK, Dogusan Z, Flamez D, Boyce M, Yuan J, Eizirik DL.

J Biol Chem. 2007 Feb 9;282(6):3989-97. Epub 2006 Dec 8.PMID: 17158450 [PubMed - indexed for MEDLINE]Related articlesFree article

The protective effect of dantrolene on ischemic neuronal cell death is associated with reduced expression of endoplasmic reticulum stress markers.

Li F, Hayashi T, Jin G, Deguchi K, Nagotani S, Nagano I, Shoji M, Chan PH, Abe K.

Brain Res. 2005 Jun 28;1048(1-2):59-68.PMID: 15921666 [PubMed - indexed for MEDLINE]Related articles

Glucose amplifies fatty acid-induced endoplasmic reticulum stress in pancreatic beta-cells via activation of mTORC1.

Bachar E, Ariav Y, Ketzinel-Gilad M, Cerasi E, Kaiser N, Leibowitz G.

PLoS One. 2009;4(3):e4954. Epub 2009 Mar 23.PMID: 19305497 [PubMed - indexed for MEDLINE]Related articlesFree article

Differential regulation of the endoplasmic reticulum stress response in pancreatic beta-cells exposed to long-chain saturated and monounsaturated fatty acids.

Diakogiannaki E, Welters HJ, Morgan NG.

J Endocrinol. 2008 Jun;197(3):553-63.PMID: 18492819 [PubMed - indexed for MEDLINE]Related articlesFree article

Chemical chaperones reduce ER stress and restore glucose homeostasis in a mouse model of type 2 diabetes.

Ozcan U, Yilmaz E, Ozcan L, Furuhashi M, Vaillancourt E, Smith RO, Görgün CZ, Hotamisligil GS.

Science. 2006 Aug 25;313(5790):1137-40.PMID: 16931765 [PubMed - indexed for MEDLINE]Related articlesFree article

Initiation and execution of lipotoxic ER stress in pancreatic beta-cells.

Cunha DA, Hekerman P, Ladrière L, Bazarra-Castro A, Ortis F, Wakeham MC, Moore F, Rasschaert J, Cardozo AK, Bellomo E, Overbergh L, Mathieu C, Lupi R, Hai T, Herchuelz A, Marchetti P, Rutter GA, Eizirik DL, Cnop M.

J Cell Sci. 2008 Jul 15;121(Pt 14):2308-18. Epub 2008 Jun 17.PMID: 18559892 [PubMed - indexed for MEDLINE]Related articlesFree article

Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes.

Ozcan U, Cao Q, Yilmaz E, Lee AH, Iwakoshi NN, Ozdelen E, Tuncman G, Görgün C, Glimcher LH, Hotamisligil GS.

Science. 2004 Oct 15;306(5695):457-61.PMID: 15486293 [PubMed - indexed for MEDLINE]Related articlesFree article

Amelioration of diabetes by imatinib mesylate (Gleevec): role of beta-cell NF-kappaB activation and anti-apoptotic preconditioning.

Hägerkvist R, Sandler S, Mokhtari D, Welsh N.

FASEB J. 2007 Feb;21(2):618-28. Epub 2006 Nov 29.PMID: 17135364 [PubMed - indexed for MEDLINE]Related articlesFree article

Roles of IP3R and RyR Ca2+ channels in endoplasmic reticulum stress and beta-cell death.

Luciani DS, Gwiazda KS, Yang TL, Kalynyak TB, Bychkivska Y, Frey MH, Jeffrey KD, Sampaio AV, Underhill TM, Johnson JD.

Diabetes. 2009 Feb;58(2):422-32. Epub 2008 Nov 25.PMID: 19033399 [PubMed - indexed for MEDLINE]Related articlesFree article