PubMed

Type 1 diabetes in the BB rat: a polygenic disease.

Wallis RH, Wang K, Marandi L, Hsieh E, Ning T, Chao GY, Sarmiento J, Paterson AD, Poussier P.

Diabetes. 2009 Apr;58(4):1007-17. Epub 2009 Jan 23.PMID: 19168599 [PubMed - indexed for MEDLINE]Related articlesFree article

A novel susceptibility locus on rat chromosome 8 affects spontaneous but not experimentally induced type 1 diabetes.

Wallis RH, Wang K, Dabrowski D, Marandi L, Ning T, Hsieh E, Paterson AD, Mordes JP, Blankenhorn EP, Poussier P.

Diabetes. 2007 Jun;56(6):1731-6. Epub 2007 Mar 27.PMID: 17389329 [PubMed - indexed for MEDLINE]Related articlesFree article

Diabetes-prone and diabetes-resistant BB rats share a common major diabetes susceptibility locus, iddm4: additional evidence for a "universal autoimmunity locus" on rat chromosome 4.

Martin AM, Maxson MN, Leif J, Mordes JP, Greiner DL, Blankenhorn EP.

Diabetes. 1999 Nov;48(11):2138-44.PMID: 10535446 [PubMed - indexed for MEDLINE]Related articlesFree article

Non-major histocompatibility complex-linked diabetes susceptibility loci on chromosomes 4 and 13 in a backcross of the DP-BB/Wor rat to the WF rat.

Martin AM, Blankenhorn EP, Maxson MN, Zhao M, Leif J, Mordes JP, Greiner DL.

Diabetes. 1999 Jan;48(1):50-8.PMID: 9892222 [PubMed - indexed for MEDLINE]Related articlesFree article

BB rat diabetes susceptibility and body weight regulation genes colocalize on chromosome 2.

Klaff LS, Koike G, Jiang J, Wang Y, Bieg S, Pettersson A, Lander E, Jacob H, Lernmark A.

Mamm Genome. 1999 Sep;10(9):883-7.PMID: 10441739 [PubMed - indexed for MEDLINE]Related articles

Introgression of F344 rat genomic DNA on BB rat chromosome 4 generates diabetes-resistant lymphopenic BB rats.

Fuller JM, Kwitek AE, Hawkins TJ, Moralejo DH, Lu W, Tupling TD, Macmurray AJ, Borchardt G, Hasinoff M, Lernmark A.

Diabetes. 2006 Dec;55(12):3351-7. Erratum in: Diabetes. 2007 Feb;56(2):549. PMID: 17130479 [PubMed - indexed for MEDLINE]Related articlesFree article

Genes of SHR rats protect spontaneously diabetic BB/OK rats from diabetes: lessons from congenic BB.SHR rat strains.

Klöting I, van den Brandt J, Kuttler B.

Biochem Biophys Res Commun. 2001 May 4;283(2):399-405.PMID: 11327715 [PubMed - indexed for MEDLINE]Related articles

Two genetic loci regulate T cell-dependent islet inflammation and drive autoimmune diabetes pathogenesis.

Fox CJ, Paterson AD, Mortin-Toth SM, Danska JS.

Am J Hum Genet. 2000 Jul;67(1):67-81. Epub 2000 Jun 9.PMID: 10848492 [PubMed - indexed for MEDLINE]Related articlesFree article

Quantitative trait loci for blood glucose confirm diabetes predisposing and protective genes, Iddm4 and Iddm5r, in the spontaneously diabetic BB/OK rat.

Klöting I, Van Den Brandt J, Kovács P.

Int J Mol Med. 1998 Nov;2(5):597-601.PMID: 9858659 [PubMed - indexed for MEDLINE]Related articles

Genetic variation in the multifunctional transcription factor Yy1 and type 1 diabetes mellitus in the BB rat.

Klöting N, Klöting I.

Mol Genet Metab. 2004 Jul;82(3):255-9.PMID: 15234341 [PubMed - indexed for MEDLINE]Related articles

A major histocompatibility complex class II restriction for BioBreeding/Worcester diabetes-inducing T cells.

Ellerman KE, Like AA.

J Exp Med. 1995 Oct 1;182(4):923-30.PMID: 7561695 [PubMed - indexed for MEDLINE]Related articlesFree article

Mapping of novel genes predisposing or protecting diabetes development in the BB/OK rat.

Klöting I, Schmidt S, Kovacs P.

Biochem Biophys Res Commun. 1998 Apr 17;245(2):483-6.PMID: 9571179 [PubMed - indexed for MEDLINE]Related articles

Alleles of diabetes-resistant BN rats contribute to insulin-dependent type 1 diabetes mellitus.

Klöting I, van den Brandt J, Klöting N, Radović B.

J Autoimmun. 2003 Mar;20(2):119-23.PMID: 12657525 [PubMed - indexed for MEDLINE]Related articles

NOD x 129.H2(g7) backcross delineates 129S1/SvImJ-derived genomic regions modulating type 1 diabetes development in mice.

Leiter EH, Reifsnyder PC, Wallace R, Li R, King B, Churchill GC.

Diabetes. 2009 Jul;58(7):1700-3. Epub 2009 Mar 31.PMID: 19336673 [PubMed - indexed for MEDLINE]Related articlesFree article

Lymphopenia in the BB rat model of type 1 diabetes is due to a mutation in a novel immune-associated nucleotide (Ian)-related gene.

MacMurray AJ, Moralejo DH, Kwitek AE, Rutledge EA, Van Yserloo B, Gohlke P, Speros SJ, Snyder B, Schaefer J, Bieg S, Jiang J, Ettinger RA, Fuller J, Daniels TL, Pettersson A, Orlebeke K, Birren B, Jacob HJ, Lander ES, Lernmark A.

Genome Res. 2002 Jul;12(7):1029-39.PMID: 12097339 [PubMed - indexed for MEDLINE]Related articlesFree article

New congenic rat strains for the separate study of MHC and non-MHC genetic effects in the development of diabetes in BB rats.

Kloeting I, Vogt L, Reetz IC, Wurst, Hedrich HJ, Guenther E.

Diabetes Res. 1990 Sep;15(1):41-5.PMID: 1983425 [PubMed - indexed for MEDLINE]Related articles

Segregation of autoimmune type 1 diabetes in a cross between diabetic BB and brown Norway rats.

Jackerott M, Hornum L, Andreasen BE, Markholst H.

J Autoimmun. 1997 Feb;10(1):35-41.PMID: 9080298 [PubMed - indexed for MEDLINE]Related articles

Genetics of the BB rat: association of autoimmune disorders (diabetes, insulitis, and thyroiditis) with lymphopenia and major histocompatibility complex class II.

Awata T, Guberski DL, Like AA.

Endocrinology. 1995 Dec;136(12):5731-5.PMID: 7588330 [PubMed - indexed for MEDLINE]Related articles

Polygenic nature of spontaneous diabetes in the rat. Permissive MHC haplotype and presence of the lymphopenic trait of the BB rat are not sufficient to produce susceptibility.

Colle E, Fuks A, Poussier P, Edouard P, Guttmann RD.

Diabetes. 1992 Dec;41(12):1617-23.PMID: 1446803 [PubMed - indexed for MEDLINE]Related articles

A single dose of the MHC-linked susceptibility determinant associated with the RT1u haplotype is permissive for insulin-dependent diabetes mellitus in the BB rat.

Fuks A, Ono SJ, Colle E, Guttmann RD.

Exp Clin Immunogenet. 1990;7(3):162-9.PMID: 1974448 [PubMed - indexed for MEDLINE]Related articles