PubMed

Mice with hyperghrelinemia are hyperphagic and glucose intolerant and have reduced leptin sensitivity.

Bewick GA, Kent A, Campbell D, Patterson M, Ghatei MA, Bloom SR, Gardiner JV.

Diabetes. 2009 Apr;58(4):840-6. Epub 2009 Jan 16.PMID: 19151202 [PubMed - indexed for MEDLINE]Related articlesFree article

Ghrelin--a new player in glucose homeostasis?

Ahima RS.

Cell Metab. 2006 May;3(5):301-2.PMID: 16679286 [PubMed - indexed for MEDLINE]Related articles

Mice with chronically increased circulating ghrelin develop age-related glucose intolerance.

Reed JA, Benoit SC, Pfluger PT, Tschöp MH, D'Alessio DA, Seeley RJ.

Am J Physiol Endocrinol Metab. 2008 Apr;294(4):E752-60. Epub 2008 Feb 12.PMID: 18270302 [PubMed - indexed for MEDLINE]Related articlesFree article

Leptin modulates orexigenic effects of ghrelin and attenuates adiponectin and insulin levels and selectively the dark-phase feeding as revealed by central leptin gene therapy.

Ueno N, Dube MG, Inui A, Kalra PS, Kalra SP.

Endocrinology. 2004 Sep;145(9):4176-84. Epub 2004 May 20.PMID: 15155574 [PubMed - indexed for MEDLINE]Related articlesFree article

Hypothalamic neuropeptide Y/Y1 receptor pathway activated by a reduction in circulating leptin, but not by an increase in circulating ghrelin, contributes to hyperphagia associated with triiodothyronine-induced thyrotoxicosis.

Ishii S, Kamegai J, Tamura H, Shimizu T, Sugihara H, Oikawa S.

Neuroendocrinology. 2003 Dec;78(6):321-30.PMID: 14688445 [PubMed - indexed for MEDLINE]Related articles

Involvement of cholecystokinin 2 receptor in food intake regulation: hyperphagia and increased fat deposition in cholecystokinin 2 receptor-deficient mice.

Clerc P, Coll Constans MG, Lulka H, Broussaud S, Guigné C, Leung-Theung-Long S, Perrin C, Knauf C, Carpéné C, Pénicaud L, Seva C, Burcelin R, Valet P, Fourmy D, Dufresne M.

Endocrinology. 2007 Mar;148(3):1039-49. Epub 2006 Nov 22.PMID: 17122076 [PubMed - indexed for MEDLINE]Related articlesFree article

Antagonism of ghrelin receptor reduces food intake and body weight gain in mice.

Asakawa A, Inui A, Kaga T, Katsuura G, Fujimiya M, Fujino MA, Kasuga M.

Gut. 2003 Jul;52(7):947-52.PMID: 12801949 [PubMed - indexed for MEDLINE]Related articlesFree article

Ablation of ghrelin improves the diabetic but not obese phenotype of ob/ob mice.

Sun Y, Asnicar M, Saha PK, Chan L, Smith RG.

Cell Metab. 2006 May;3(5):379-86.PMID: 16679295 [PubMed - indexed for MEDLINE]Related articles

Evidence for the existence of distinct central appetite, energy expenditure, and ghrelin stimulation pathways as revealed by hypothalamic site-specific leptin gene therapy.

Bagnasco M, Dube MG, Kalra PS, Kalra SP.

Endocrinology. 2002 Nov;143(11):4409-21.PMID: 12399438 [PubMed - indexed for MEDLINE]Related articlesFree article

Overeating of palatable food is associated with blunted leptin and ghrelin responses.

Lindqvist A, de la Cour CD, Stegmark A, Håkanson R, Erlanson-Albertsson C.

Regul Pept. 2005 Sep 15;130(3):123-32.PMID: 15964641 [PubMed - indexed for MEDLINE]Related articles

Altered postprandial glucose, insulin, leptin, and ghrelin in liver cirrhosis: correlations with energy intake and resting energy expenditure.

Kalaitzakis E, Bosaeus I, Ohman L, Björnsson E.

Am J Clin Nutr. 2007 Mar;85(3):808-15.PMID: 17344504 [PubMed - indexed for MEDLINE]Related articlesFree article

Peripheral signals conveying metabolic information to the brain: short-term and long-term regulation of food intake and energy homeostasis.

Havel PJ.

Exp Biol Med (Maywood). 2001 Dec;226(11):963-77. Review.PMID: 11743131 [PubMed - indexed for MEDLINE]Related articlesFree article

Ghrelin is an appetite-stimulatory signal from stomach with structural resemblance to motilin.

Asakawa A, Inui A, Kaga T, Yuzuriha H, Nagata T, Ueno N, Makino S, Fujimiya M, Niijima A, Fujino MA, Kasuga M.

Gastroenterology. 2001 Feb;120(2):337-45.PMID: 11159873 [PubMed - indexed for MEDLINE]Related articles

Post-embryonic ablation of AgRP neurons in mice leads to a lean, hypophagic phenotype.

Bewick GA, Gardiner JV, Dhillo WS, Kent AS, White NE, Webster Z, Ghatei MA, Bloom SR.

FASEB J. 2005 Oct;19(12):1680-2. Epub 2005 Aug 11.PMID: 16099943 [PubMed - indexed for MEDLINE]Related articlesFree article

Leptin gene transfer in the hypothalamus enhances longevity in adult monogenic mutant mice in the absence of circulating leptin.

Boghossian S, Ueno N, Dube MG, Kalra P, Kalra S.

Neurobiol Aging. 2007 Oct;28(10):1594-604. Epub 2006 Sep 29.PMID: 17011078 [PubMed - indexed for MEDLINE]Related articles

Sex-associated differences in the leptin and ghrelin systems related with the induction of hyperphagia under high-fat diet exposure in rats.

Priego T, Sánchez J, Picó C, Palou A.

Horm Behav. 2009 Jan;55(1):33-40. Epub 2008 Jul 31.PMID: 18718472 [PubMed - indexed for MEDLINE]Related articles

The inhibition of gastric ghrelin production by food intake in rats is dependent on the type of macronutrient.

Sánchez J, Oliver P, Palou A, Picó C.

Endocrinology. 2004 Nov;145(11):5049-55. Epub 2004 Jul 29.PMID: 15284203 [PubMed - indexed for MEDLINE]Related articlesFree article

Effect of des-acyl ghrelin on adiposity and glucose metabolism.

Zhang W, Chai B, Li JY, Wang H, Mulholland MW.

Endocrinology. 2008 Sep;149(9):4710-6. Epub 2008 Jun 5.PMID: 18535105 [PubMed - indexed for MEDLINE]Related articlesFree article

A mouse model of ghrelinoma exhibited activated growth hormone-insulin-like growth factor I axis and glucose intolerance.

Iwakura H, Ariyasu H, Li Y, Kanamoto N, Bando M, Yamada G, Hosoda H, Hosoda K, Shimatsu A, Nakao K, Kangawa K, Akamizu T.

Am J Physiol Endocrinol Metab. 2009 Sep;297(3):E802-11. Epub 2009 Jul 14.PMID: 19602582 [PubMed - indexed for MEDLINE]Related articles

Hyperphagia alters expression of hypothalamic 5-HT2C and 5-HT1B receptor genes and plasma des-acyl ghrelin levels in Ay mice.

Nonogaki K, Nozue K, Oka Y.

Endocrinology. 2006 Dec;147(12):5893-900. Epub 2006 Sep 14.PMID: 16973729 [PubMed - indexed for MEDLINE]Related articlesFree article