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    Results: 1 to 20 of 116

    1.

    Survey of the human pancreatic beta-cell G1/S proteome reveals a potential therapeutic role for cdk-6 and cyclin D1 in enhancing human beta-cell replication and function in vivo.

    Fiaschi-Taesch N, Bigatel TA, Sicari B, Takane KK, Salim F, Velazquez-Garcia S, Harb G, Selk K, Cozar-Castellano I, Stewart AF.

    Diabetes. 2009 Apr;58(4):882-93. Epub 2009 Jan 9.PMID: 19136653 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    Induction of beta-cell proliferation and retinoblastoma protein phosphorylation in rat and human islets using adenovirus-mediated transfer of cyclin-dependent kinase-4 and cyclin D1.

    Cozar-Castellano I, Takane KK, Bottino R, Balamurugan AN, Stewart AF.

    Diabetes. 2004 Jan;53(1):149-59.PMID: 14693709 [PubMed - indexed for MEDLINE]Related articlesFree article

    3.

    Lessons from the first comprehensive molecular characterization of cell cycle control in rodent insulinoma cell lines.

    Cozar-Castellano I, Harb G, Selk K, Takane K, Vasavada R, Sicari B, Law B, Zhang P, Scott DK, Fiaschi-Taesch N, Stewart AF.

    Diabetes. 2008 Nov;57(11):3056-68. Epub 2008 Jul 23.PMID: 18650366 [PubMed - indexed for MEDLINE]Related articlesFree article

    4.

    Effects of cyclin D1 overexpression on G1 progression-related events.

    Imoto M, Doki Y, Jiang W, Han EK, Weinstein IB.

    Exp Cell Res. 1997 Oct 10;236(1):173-80.PMID: 9344597 [PubMed - indexed for MEDLINE]Related articles

    5.

    Evaluation of beta-cell replication in mice transgenic for hepatocyte growth factor and placental lactogen: comprehensive characterization of the G1/S regulatory proteins reveals unique involvement of p21cip.

    Cozar-Castellano I, Weinstock M, Haught M, Velázquez-Garcia S, Sipula D, Stewart AF.

    Diabetes. 2006 Jan;55(1):70-7.PMID: 16380478 [PubMed - indexed for MEDLINE]Related articlesFree article

    6.

    TGF-beta1-induced cell cycle arrest in renal mesangial cells involves inhibition of cyclin E-cdk 2 activation and retinoblastoma protein phosphorylation.

    Schoecklmann HO, Rupprecht HD, Zauner I, Sterzel RB.

    Kidney Int. 1997 Apr;51(4):1228-36.PMID: 9083291 [PubMed - indexed for MEDLINE]Related articles

    8.

    lin-35 Rb and cki-1 Cip/Kip cooperate in developmental regulation of G1 progression in C. elegans.

    Boxem M, van den Heuvel S.

    Development. 2001 Nov;128(21):4349-59.PMID: 11684669 [PubMed - indexed for MEDLINE]Related articlesFree article

    9.

    Multifaceted regulation of cell cycle progression by estrogen: regulation of Cdk inhibitors and Cdc25A independent of cyclin D1-Cdk4 function.

    Foster JS, Henley DC, Bukovsky A, Seth P, Wimalasena J.

    Mol Cell Biol. 2001 Feb;21(3):794-810.PMID: 11154267 [PubMed - indexed for MEDLINE]Related articlesFree article

    10.

    Saucernetin-7 isolated from Saururus chinensis inhibits proliferation of human promyelocytic HL-60 leukemia cells via G0/G1 phase arrest and induction of differentiation.

    Seo BR, Lee KW, Ha J, Park HJ, Choi JW, Lee KT.

    Carcinogenesis. 2004 Aug;25(8):1387-94. Epub 2004 Mar 19.PMID: 15033903 [PubMed - indexed for MEDLINE]Related articlesFree article

    11.

    Downregulation of cyclin D1 alters cdk 4- and cdk 2-specific phosphorylation of retinoblastoma protein.

    Yu B, Lane ME, Pestell RG, Albanese C, Wadler S.

    Mol Cell Biol Res Commun. 2000 Jun;3(6):352-9.PMID: 11032757 [PubMed - indexed for MEDLINE]Related articles

    12.

    Induction of cell cycle regulatory proteins in anti-immunoglobulin-stimulated mature B lymphocytes.

    Solvason N, Wu WW, Kabra N, Wu X, Lees E, Howard MC.

    J Exp Med. 1996 Aug 1;184(2):407-17.PMID: 8760794 [PubMed - indexed for MEDLINE]Related articlesFree article

    13.

    IGF-I mediates regeneration of endocrine pancreas by increasing beta cell replication through cell cycle protein modulation in mice.

    Agudo J, Ayuso E, Jimenez V, Salavert A, Casellas A, Tafuro S, Haurigot V, Ruberte J, Segovia JC, Bueren J, Bosch F.

    Diabetologia. 2008 Oct;51(10):1862-72. Epub 2008 Jul 29.PMID: 18663428 [PubMed - indexed for MEDLINE]Related articles

    14.

    Cyclin D1 is dispensable for G1 control in retinoblastoma gene-deficient cells independently of cdk4 activity.

    Lukas J, Bartkova J, Rohde M, Strauss M, Bartek J.

    Mol Cell Biol. 1995 May;15(5):2600-11.PMID: 7739541 [PubMed - indexed for MEDLINE]Related articlesFree article

    15.

    Cycling to cancer with cyclin D1.

    Diehl JA.

    Cancer Biol Ther. 2002 May-Jun;1(3):226-31. Review.PMID: 12432268 [PubMed - indexed for MEDLINE]Related articles

    16.

    Overexpression of pre-pro-cholecystokinin stimulates beta-cell proliferation in mouse and human islets with retention of islet function.

    Lavine JA, Raess PW, Davis DB, Rabaglia ME, Presley BK, Keller MP, Beinfeld MC, Kopin AS, Newgard CB, Attie AD.

    Mol Endocrinol. 2008 Dec;22(12):2716-28. Epub 2008 Oct 9.PMID: 18845673 [PubMed - indexed for MEDLINE]Related articles

    17.

    The retinoblastoma protein and its homolog p130 regulate the G1/S transition in pancreatic beta-cells.

    Harb G, Vasavada RC, Cobrinik D, Stewart AF.

    Diabetes. 2009 Aug;58(8):1852-62. Epub 2009 Jun 9. Erratum in: Diabetes. 2009 Oct;58(10):2425. PMID: 19509021 [PubMed - indexed for MEDLINE]Related articlesFree article

    18.

    [Molecular mechanisms controlling the cell cycle: fundamental aspects and implications for oncology]

    Viallard JF, Lacombe F, Belloc F, Pellegrin JL, Reiffers J.

    Cancer Radiother. 2001 Apr;5(2):109-29. Review. French. PMID: 11355576 [PubMed - indexed for MEDLINE]Related articles

    19.

    Protein kinase C-zeta activation markedly enhances beta-cell proliferation: an essential role in growth factor mediated beta-cell mitogenesis.

    Vasavada RC, Wang L, Fujinaka Y, Takane KK, Rosa TC, Mellado-Gil JM, Friedman PA, Garcia-Ocaña A.

    Diabetes. 2007 Nov;56(11):2732-43. Epub 2007 Aug 8.PMID: 17686945 [PubMed - indexed for MEDLINE]Related articlesFree article

    20.

    The cell cycle inhibitory protein p21cip is not essential for maintaining beta-cell cycle arrest or beta-cell function in vivo.

    Cozar-Castellano I, Haught M, Stewart AF.

    Diabetes. 2006 Dec;55(12):3271-8.PMID: 17130470 [PubMed - indexed for MEDLINE]Related articlesFree article

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