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    Results: 1 to 20 of 123

    1.

    Differential effects of 24-hydroxycholesterol and 27-hydroxycholesterol on beta-amyloid precursor protein levels and processing in human neuroblastoma SH-SY5Y cells.

    Prasanthi JR, Huls A, Thomasson S, Thompson A, Schommer E, Ghribi O.

    Mol Neurodegener. 2009 Jan 6;4:1.PMID: 19126211 [PubMed - in process]Related articlesFree article

    2.

    Regulation of alpha- and beta-secretase activity by oxysterols: cerebrosterol stimulates processing of APP via the alpha-secretase pathway.

    Famer D, Meaney S, Mousavi M, Nordberg A, Björkhem I, Crisby M.

    Biochem Biophys Res Commun. 2007 Jul 20;359(1):46-50. Epub 2007 May 14.PMID: 17532301 [PubMed - indexed for MEDLINE]Related articles

    3.

    Upregulation of CRABP1 in human neuroblastoma cells overproducing the Alzheimer-typical Abeta42 reduces their differentiation potential.

    Uhrig M, Brechlin P, Jahn O, Knyazev Y, Weninger A, Busia L, Honarnejad K, Otto M, Hartmann T.

    BMC Med. 2008 Dec 16;6:38.PMID: 19087254 [PubMed - indexed for MEDLINE]Related articlesFree article

    4.

    Down-regulation of seladin-1 increases BACE1 levels and activity through enhanced GGA3 depletion during apoptosis.

    Sarajärvi T, Haapasalo A, Viswanathan J, Mäkinen P, Laitinen M, Soininen H, Hiltunen M.

    J Biol Chem. 2009 Dec 4;284(49):34433-43. Epub 2009 Oct 8.PMID: 19815556 [PubMed - indexed for MEDLINE]Related articles

    5.

    The liver X receptor ligand T0901317 decreases amyloid beta production in vitro and in a mouse model of Alzheimer's disease.

    Koldamova RP, Lefterov IM, Staufenbiel M, Wolfe D, Huang S, Glorioso JC, Walter M, Roth MG, Lazo JS.

    J Biol Chem. 2005 Feb 11;280(6):4079-88. Epub 2004 Nov 22.PMID: 15557325 [PubMed - indexed for MEDLINE]Related articlesFree article

    6.

    Induction of the cholesterol transporter ABCA1 in central nervous system cells by liver X receptor agonists increases secreted Abeta levels.

    Fukumoto H, Deng A, Irizarry MC, Fitzgerald ML, Rebeck GW.

    J Biol Chem. 2002 Dec 13;277(50):48508-13. Epub 2002 Oct 15.PMID: 12384498 [PubMed - indexed for MEDLINE]Related articlesFree article

    7.

    Oxysterol-binding protein-1 (OSBP1) modulates processing and trafficking of the amyloid precursor protein.

    Zerbinatti CV, Cordy JM, Chen CD, Guillily M, Suon S, Ray WJ, Seabrook GR, Abraham CR, Wolozin B.

    Mol Neurodegener. 2008 Mar 18;3:5.PMID: 18348724 [PubMed - in process]Related articlesFree article

    8.

    The cholesterol transporter ABCG1 modulates the subcellular distribution and proteolytic processing of beta-amyloid precursor protein.

    Tansley GH, Burgess BL, Bryan MT, Su Y, Hirsch-Reinshagen V, Pearce J, Chan JY, Wilkinson A, Evans J, Naus KE, McIsaac S, Bromley K, Song W, Yang HC, Wang N, DeMattos RB, Wellington CL.

    J Lipid Res. 2007 May;48(5):1022-34. Epub 2007 Feb 10.PMID: 17293612 [PubMed - indexed for MEDLINE]Related articlesFree article

    9.

    New protein kinase C activator regulates amyloid precursor protein processing in vitro by increasing alpha-secretase activity.

    Yang HQ, Pan J, Ba MW, Sun ZK, Ma GZ, Lu GQ, Xiao Q, Chen SD.

    Eur J Neurosci. 2007 Jul;26(2):381-91.PMID: 17650113 [PubMed - indexed for MEDLINE]Related articles

    10.

    Targeting ADAM10 to lipid rafts in neuroblastoma SH-SY5Y cells impairs amyloidogenic processing of the amyloid precursor protein.

    Harris B, Pereira I, Parkin E.

    Brain Res. 2009 Nov 3;1296:203-15. Epub 2009 Aug 11.PMID: 19679113 [PubMed - indexed for MEDLINE]Related articles

    11.

    Differential effects of 24-hydroxycholesterol and 27-hydroxycholesterol on tyrosine hydroxylase and alpha-synuclein in human neuroblastoma SH-SY5Y cells.

    Rantham Prabhakara JP, Feist G, Thomasson S, Thompson A, Schommer E, Ghribi O.

    J Neurochem. 2008 Dec;107(6):1722-9. Epub 2008 Nov 5.PMID: 19014385 [PubMed - indexed for MEDLINE]Related articles

    12.

    Zinc Inhibits Amyloid beta Production from Alzheimer's Amyloid Precursor Protein in SH-SY5Y Cells.

    Lee J, Kim CH, Kim DG, Ahn YS.

    Korean J Physiol Pharmacol. 2009 Jun;13(3):195-200. Epub 2009 Jun 30.PMID: 19885037 [PubMed - in process]Related articlesFree article

    13.

    Differential expression of cholesterol hydroxylases in Alzheimer's disease.

    Brown J 3rd, Theisler C, Silberman S, Magnuson D, Gottardi-Littell N, Lee JM, Yager D, Crowley J, Sambamurti K, Rahman MM, Reiss AB, Eckman CB, Wolozin B.

    J Biol Chem. 2004 Aug 13;279(33):34674-81. Epub 2004 May 17.PMID: 15148325 [PubMed - indexed for MEDLINE]Related articlesFree article

    14.

    Cryptotanshinone, a compound from Salvia miltiorrhiza modulates amyloid precursor protein metabolism and attenuates beta-amyloid deposition through upregulating alpha-secretase in vivo and in vitro.

    Mei Z, Zhang F, Tao L, Zheng W, Cao Y, Wang Z, Tang S, Le K, Chen S, Pi R, Liu P.

    Neurosci Lett. 2009 Mar 13;452(2):90-5. Epub 2009 Jan 13.PMID: 19154776 [PubMed - indexed for MEDLINE]Related articles

    15.

    Nicotinic receptor agonists and antagonists increase sAPPalpha secretion and decrease Abeta levels in vitro.

    Mousavi M, Hellström-Lindahl E.

    Neurochem Int. 2009 Mar-Apr;54(3-4):237-44. Epub 2008 Dec 7.PMID: 19111588 [PubMed - indexed for MEDLINE]Related articles

    16.

    The role of amyloid beta peptide 42 in Alzheimer's disease.

    Findeis MA.

    Pharmacol Ther. 2007 Nov;116(2):266-86. Epub 2007 Jul 17. Review.PMID: 17716740 [PubMed - indexed for MEDLINE]Related articles

    17.

    Role of ABCG1 and ABCA1 in regulation of neuronal cholesterol efflux to apolipoprotein E discs and suppression of amyloid-beta peptide generation.

    Kim WS, Rahmanto AS, Kamili A, Rye KA, Guillemin GJ, Gelissen IC, Jessup W, Hill AF, Garner B.

    J Biol Chem. 2007 Feb 2;282(5):2851-61. Epub 2006 Nov 22.PMID: 17121837 [PubMed - indexed for MEDLINE]Related articlesFree article

    18.

    Leptin is Involved in Accumulation of Amyloid-beta and Tau Phosphorylation Induced by 27-Hydroxycholesterol in Organotypic Slices from Adult Rabbit Hippocampus.

    Marwarha G, Dasari B, Prasanthi JR, Schommer J, Ghribi O.

    J Alzheimers Dis. . [Epub ahead of print]PMID: 20009233 [PubMed - as supplied by publisher]Related articles

    19.

    Modulation of Abeta generation by small ubiquitin-like modifiers does not require conjugation to target proteins.

    Dorval V, Mazzella MJ, Mathews PM, Hay RT, Fraser PE.

    Biochem J. 2007 Jun 1;404(2):309-16.PMID: 17346237 [PubMed - indexed for MEDLINE]Related articlesFree article

    20.

    APP-BP1 inhibits Abeta42 levels by interacting with Presenilin-1.

    Chen Y, Bodles AM, McPhie DL, Neve RL, Mrak RE, Griffin WS.

    Mol Neurodegener. 2007 Feb 7;2:3.PMID: 17286867 [PubMed]Related articlesFree article

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