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Expression of sterol regulatory element-binding transcription factor (SREBF) 2 and SREBF cleavage-activating protein (SCAP) in human atheroma and the association of their allelic variants with sudden cardiac death.

Fan YM, Karhunen PJ, Levula M, Ilveskoski E, Mikkelsson J, Kajander OA, Järvinen O, Oksala N, Thusberg J, Vihinen M, Salenius JP, Kytömäki L, Soini JT, Laaksonen R, Lehtimäki T.

Thromb J. 2008 Dec 30;6:17.PMID: 19116028 [PubMed - in process]Related articlesFree article

Sterol regulatory element-binding transcription factor (SREBF)-2, SREBF cleavage-activating protein (SCAP), and premature coronary artery disease in a Chinese population.

Chen Z, Ding Z, Ma G, Liu N, Qian Q.

Mol Biol Rep. 2010 Jan 29. [Epub ahead of print]PMID: 20111910 [PubMed - as supplied by publisher]Related articles

Effects of SREBF-1a and SCAP polymorphisms on plasma levels of lipids, severity, progression and regression of coronary atherosclerosis and response to therapy with fluvastatin.

Salek L, Lutucuta S, Ballantyne CM, Gotto Jr AM, Marian AJ.

J Mol Med. 2002 Nov;80(11):737-44. Epub 2002 Sep 11.PMID: 12436350 [PubMed - indexed for MEDLINE]Related articles

SREBP-2 and SCAP isoforms and risk of early onset myocardial infarction.

Friedlander Y, Schwartz SM, Durst R, Meiner V, Robertson AS, Erez G, Leitersdorf E, Siscovick DS.

Atherosclerosis. 2008 Feb;196(2):896-904. Epub 2007 Mar 26.PMID: 17383658 [PubMed - indexed for MEDLINE]Related articles

Determinants of variable response to simvastatin treatment: the role of common variants of SCAP, SREBF-1a and SREBF-2 genes.

Fiegenbaum M, Silveira FR, Van der Sand CR, Van der Sand LC, Ferreira ME, Pires RC, Hutz MH.

Pharmacogenomics J. 2005;5(6):359-64.PMID: 16158080 [PubMed - indexed for MEDLINE]Related articles

Age-dependent association between hepatic lipase gene C-480T polymorphism and the risk of pre-hospital sudden cardiac death: the Helsinki Sudden Death Study.

Fan YM, Lehtimäki T, Rontu R, Ilveskoski E, Goebeler S, Kajander O, Mikkelsson J, Perola M, Karhunen PJ.

Atherosclerosis. 2007 Jun;192(2):421-7. Epub 2006 Jun 21.PMID: 16793047 [PubMed - indexed for MEDLINE]Related articles

Interleukin 18 gene promoter polymorphism: a link between hypertension and pre-hospital sudden cardiac death: the Helsinki Sudden Death Study.

Hernesniemi JA, Karhunen PJ, Oksala N, Kähönen M, Levula M, Rontu R, Ilveskoski E, Kajander O, Goebeler S, Viiri LE, Hurme M, Lehtimäki T.

Eur Heart J. 2009 Dec;30(23):2939-46. Epub 2009 Aug 17.PMID: 19687159 [PubMed - in process]Related articles

The hepatic lipase gene C-480T polymorphism in the development of early coronary atherosclerosis: the Helsinki Sudden Death Study.

Fan YM, Lehtimäki T, Rontu R, Ilveskoski E, Goebeler S, Kajander O, Mikkelsson J, Viiri LE, Perola M, Karhunen PJ.

Eur J Clin Invest. 2007 Jun;37(6):472-7.PMID: 17537154 [PubMed - indexed for MEDLINE]Related articles

Coronary artery wall atherosclerosis in relation to the estrogen receptor 1 gene polymorphism: an autopsy study.

Lehtimäki T, Kunnas TA, Mattila KM, Perola M, Penttilä A, Koivula T, Karhunen PJ.

J Mol Med. 2002 Mar;80(3):176-80. Epub 2002 Jan 17.PMID: 11894143 [PubMed - indexed for MEDLINE]Related articles

Association of paraoxonase-1 M55L genotype and alcohol consumption with coronary atherosclerosis: the Helsinki Sudden Death Study.

Rontu R, Lehtimäki T, Ilveskoski E, Mikkelsson J, Kajander O, Goebeler S, Perola M, Penttilä A, Karhunen PJ.

Pharmacogenetics. 2004 Aug;14(8):479-85.PMID: 15284530 [PubMed - indexed for MEDLINE]Related articles

The discrete and combined effect of SREBP-2 and SCAP isoforms in the control of plasma lipids among familial hypercholesterolaemia patients.

Durst R, Jansen A, Erez G, Bravdo R, Butbul E, Ben Avi L, Shpitzen S, Lotan C, Leitersdorf E, Defesche J, Friedlander Y, Meiner V, Miserez AR.

Atherosclerosis. 2006 Dec;189(2):443-50. Epub 2006 Feb 8.PMID: 16466730 [PubMed - indexed for MEDLINE]Related articles

Neuropeptide Y signal peptide Pro7 substitution protects against coronary artery atherosclerosis: the Helsinki Sudden Death Study.

Ilveskoski E, Viiri LE, Mikkelsson J, Pörsti I, Lehtimäki T, Karhunen PJ.

Atherosclerosis. 2008 Aug;199(2):445-50. Epub 2007 Dec 4.PMID: 18054939 [PubMed - indexed for MEDLINE]Related articles

ADAM8 and its single nucleotide polymorphism 2662 T/G are associated with advanced atherosclerosis and fatal myocardial infarction: Tampere vascular study.

Levula M, Airla N, Oksala N, Hernesniemi JA, Pelto-Huikko M, Salenius JP, Zeitlin R, Jarvinen O, Huovila AP, Nikkari ST, Jaakkola O, Ilveskoski E, Mikkelsson J, Perola M, Laaksonen R, Kytomaki L, Soini JT, Kahonen M, Parkkinen J, Karhunen PJ, Lehtimaki T.

Ann Med. 2009 Jul 2:1-11. [Epub ahead of print]PMID: 19575316 [PubMed - as supplied by publisher]Related articles

Association analysis of allelic variants of USF1 in coronary atherosclerosis.

Kristiansson K, Ilveskoski E, Lehtimäki T, Peltonen L, Perola M, Karhunen PJ.

Arterioscler Thromb Vasc Biol. 2008 May;28(5):983-9. Epub 2008 Feb 14.PMID: 18276913 [PubMed - indexed for MEDLINE]Related articlesFree article

Matrix metalloproteinase3 and 9 gene promoter polymorphisms: joint action of two loci as a risk factor for coronary artery complicated plaques.

Pöllänen PJ, Lehtimäki T, Mikkelsson J, Ilveskoski E, Kunnas T, Perola M, Penttilä A, Mattila KM, Nikkari ST, Syrjäkoski K, Karhunen PJ.

Atherosclerosis. 2005 May;180(1):73-8. Epub 2004 Dec 18.PMID: 15823277 [PubMed - indexed for MEDLINE]Related articles

Interleukin-18 promoter polymorphism associates with the occurrence of sudden cardiac death among Caucasian males: the Helsinki Sudden Death Study.

Hernesniemi JA, Karhunen PJ, Rontu R, Ilveskoski E, Kajander O, Goebeler S, Viiri LE, Pessi T, Hurme M, Lehtimäki T.

Atherosclerosis. 2008 Feb;196(2):643-9. Epub 2007 Aug 31.PMID: 17765248 [PubMed - indexed for MEDLINE]Related articles

Genetic variant of the SREBF-1 gene is significantly related to cholesterol synthesis in man.

Laaksonen R, Thelen KM, Päivä H, Matinheikki J, Vesalainen R, Janatuinen T, Knuuti J, Rontu R, von Bergmann K, Lütjohann D, Lehtimäki T.

Atherosclerosis. 2006 Mar;185(1):206-9. Epub 2005 Jul 11.PMID: 16005884 [PubMed - indexed for MEDLINE]Related articles

Myeloperoxidase gene variation as a determinant of atherosclerosis progression in the abdominal and thoracic aorta: an autopsy study.

Mäkelä R, Karhunen PJ, Kunnas TA, Ilveskoski E, Kajander OA, Mikkelsson J, Perola M, Penttilä A, Lehtimäki T.

Lab Invest. 2003 Jul;83(7):919-25.PMID: 12861032 [PubMed - indexed for MEDLINE]Related articles

Interactions among genetic variants from SREBP2 activating-related pathway on risk of coronary heart disease in Chinese Han population.

Liu X, Li Y, Lu X, Wang L, Zhao Q, Yang W, Huang J, Cao J, Li H, Gu D.

Atherosclerosis. 2010 Feb;208(2):421-6. Epub 2009 Aug 14.PMID: 19740467 [PubMed - in process]Related articles

Silencing of the mutant SCAP allele accounts for restoration of a normal phenotype in CT60 cells selected for NPC1 expression.

Maguire JA, Reagan JW Jr.

J Lipid Res. 2005 Sep;46(9):1840-8. Epub 2005 Jul 1.PMID: 15995170 [PubMed - indexed for MEDLINE]Related articlesFree article