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    Results: 1 to 20 of 326

    1.

    Cilengitide induces cellular detachment and apoptosis in endothelial and glioma cells mediated by inhibition of FAK/src/AKT pathway.

    Oliveira-Ferrer L, Hauschild J, Fiedler W, Bokemeyer C, Nippgen J, Celik I, Schuch G.

    J Exp Clin Cancer Res. 2008 Dec 29;27:86.PMID: 19114005 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    The integrin antagonist cilengitide activates alphaVbeta3, disrupts VE-cadherin localization at cell junctions and enhances permeability in endothelial cells.

    Alghisi GC, Ponsonnet L, Rüegg C.

    PLoS One. 2009;4(2):e4449. Epub 2009 Feb 12.PMID: 19212436 [PubMed - indexed for MEDLINE]Related articlesFree article

    3.

    Cilengitide modulates attachment and viability of human glioma cells, but not sensitivity to irradiation or temozolomide in vitro.

    Maurer GD, Tritschler I, Adams B, Tabatabai G, Wick W, Stupp R, Weller M.

    Neuro Oncol. 2009 Dec;11(6):747-56. Epub .PMID: 19221171 [PubMed - indexed for MEDLINE]Related articles

    4.

    Radiation sensitization of glioblastoma by cilengitide has unanticipated schedule-dependency.

    Mikkelsen T, Brodie C, Finniss S, Berens ME, Rennert JL, Nelson K, Lemke N, Brown SL, Hahn D, Neuteboom B, Goodman SL.

    Int J Cancer. 2009 Jun 1;124(11):2719-27.PMID: 19199360 [PubMed - indexed for MEDLINE]Related articles

    5.

    Effect of IFN-beta on human glioma cell lines with temozolomide resistance.

    Yoshino A, Ogino A, Yachi K, Ohta T, Fukushima T, Watanabe T, Katayama Y, Okamoto Y, Naruse N, Sano E.

    Int J Oncol. 2009 Jul;35(1):139-48.PMID: 19513561 [PubMed - indexed for MEDLINE]Related articles

    6.

    The integrin antagonist cilengitide increases the antitumor activity of temozolomide against malignant melanoma.

    Tentori L, Dorio AS, Muzi A, Lacal PM, Ruffini F, Navarra P, Graziani G.

    Oncol Rep. 2008 Apr;19(4):1039-43.PMID: 18357394 [PubMed - indexed for MEDLINE]Related articles

    7.

    Integrin alpha v beta 3 antagonist Cilengitide enhances efficacy of radiotherapy in endothelial cell and non-small-cell lung cancer models.

    Albert JM, Cao C, Geng L, Leavitt L, Hallahan DE, Lu B.

    Int J Radiat Oncol Biol Phys. 2006 Aug 1;65(5):1536-43.PMID: 16863930 [PubMed - indexed for MEDLINE]Related articles

    8.

    The PTEN/Akt pathway dictates the direct alphaVbeta3-dependent growth-inhibitory action of an active fragment of tumstatin in glioma cells in vitro and in vivo.

    Kawaguchi T, Yamashita Y, Kanamori M, Endersby R, Bankiewicz KS, Baker SJ, Bergers G, Pieper RO.

    Cancer Res. 2006 Dec 1;66(23):11331-40.PMID: 17145879 [PubMed - indexed for MEDLINE]Related articlesFree article

    9.

    O6-methylguanine-DNA methyltransferase is downregulated in transformed astrocyte cells: implications for anti-glioma therapies.

    Sasai K, Akagi T, Aoyanagi E, Tabu K, Kaneko S, Tanaka S.

    Mol Cancer. 2007 Jun 5;6:36.PMID: 17547775 [PubMed - indexed for MEDLINE]Related articlesFree article

    10.

    Potent mimicry of fibronectin-induced intracellular signaling in glioma cells by the homodimeric snake venom disintegrin contortrostatin.

    Schmitmeier S, Markland FS, Schönthal AH, Chen TC.

    Neurosurgery. 2005 Jul;57(1):141-53; discussion 141-53.PMID: 15987550 [PubMed - indexed for MEDLINE]Related articles

    11.

    Perifosine inhibits multiple signaling pathways in glial progenitors and cooperates with temozolomide to arrest cell proliferation in gliomas in vivo.

    Momota H, Nerio E, Holland EC.

    Cancer Res. 2005 Aug 15;65(16):7429-35.PMID: 16103096 [PubMed - indexed for MEDLINE]Related articlesFree article

    12.

    Cilengitide targeting of alpha(v)beta(3) integrin receptor synergizes with radioimmunotherapy to increase efficacy and apoptosis in breast cancer xenografts.

    Burke PA, DeNardo SJ, Miers LA, Lamborn KR, Matzku S, DeNardo GL.

    Cancer Res. 2002 Aug 1;62(15):4263-72.PMID: 12154028 [PubMed - indexed for MEDLINE]Related articlesFree article

    13.

    Folate supplementation limits the aggressiveness of glioma via the remethylation of DNA repeats element and genes governing apoptosis and proliferation.

    Hervouet E, Debien E, Campion L, Charbord J, Menanteau J, Vallette FM, Cartron PF.

    Clin Cancer Res. 2009 May 15;15(10):3519-29.PMID: 19451595 [PubMed - indexed for MEDLINE]Related articles

    14.

    The unfolded protein response regulator GRP78/BiP as a novel target for increasing chemosensitivity in malignant gliomas.

    Pyrko P, Schönthal AH, Hofman FM, Chen TC, Lee AS.

    Cancer Res. 2007 Oct 15;67(20):9809-16.PMID: 17942911 [PubMed - indexed for MEDLINE]Related articlesFree article

    15.

    Extracellular pressure stimulates tumor cell adhesion in vitro by paxillin activation.

    van Zyp JV, Conway WC, Craig DH, van Zyp NV, Thamilselvan V, Basson MD.

    Cancer Biol Ther. 2006 Sep;5(9):1169-78. Epub 2006 Sep 6.PMID: 16855384 [PubMed - indexed for MEDLINE]Related articles

    16.

    Methylselenol generated from selenomethionine by methioninase downregulates integrin expression and induces caspase-mediated apoptosis of B16F10 melanoma cells.

    Kim A, Oh JH, Park JM, Chung AS.

    J Cell Physiol. 2007 Aug;212(2):386-400.PMID: 17348006 [PubMed - indexed for MEDLINE]Related articles

    17.

    Cilengitide inhibits proliferation and differentiation of human endothelial progenitor cells in vitro.

    Loges S, Butzal M, Otten J, Schweizer M, Fischer U, Bokemeyer C, Hossfeld DK, Schuch G, Fiedler W.

    Biochem Biophys Res Commun. 2007 Jun 15;357(4):1016-20. Epub 2007 Apr 19.PMID: 17466276 [PubMed - indexed for MEDLINE]Related articles

    18.

    Clinical features, mechanisms, and management of pseudoprogression in malignant gliomas.

    Brandsma D, Stalpers L, Taal W, Sminia P, van den Bent MJ.

    Lancet Oncol. 2008 May;9(5):453-61. Review.PMID: 18452856 [PubMed - indexed for MEDLINE]Related articles

    19.

    Human cytomegalovirus induces cellular tyrosine kinase signaling and promotes glioma cell invasiveness.

    Cobbs CS, Soroceanu L, Denham S, Zhang W, Britt WJ, Pieper R, Kraus MH.

    J Neurooncol. 2007 Dec;85(3):271-80. Epub 2007 Jun 23.PMID: 17589804 [PubMed - indexed for MEDLINE]Related articles

    20.

    Shp2 negatively regulates growth in cardiomyocytes by controlling focal adhesion kinase/Src and mTOR pathways.

    Marin TM, Clemente CF, Santos AM, Picardi PK, Pascoal VD, Lopes-Cendes I, Saad MJ, Franchini KG.

    Circ Res. 2008 Oct 10;103(8):813-24. Epub 2008 Aug 28.PMID: 18757826 [PubMed - indexed for MEDLINE]Related articlesFree article

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