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    Results: 1 to 20 of 100

    1.

    Polymorphisms in the GTP cyclohydrolase gene (GCH1) are associated with ratings of capsaicin pain.

    Campbell CM, Edwards RR, Carmona C, Uhart M, Wand G, Carteret A, Kim YK, Frost J, Campbell JN.

    Pain. 2009 Jan;141(1-2):114-8. Epub 2008 Dec 9.PMID: 19081190 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    Reliable screening for a pain-protective haplotype in the GTP cyclohydrolase 1 gene (GCH1) through the use of 3 or fewer single nucleotide polymorphisms.

    Lötsch J, Belfer I, Kirchhof A, Mishra BK, Max MB, Doehring A, Costigan M, Woolf CJ, Geisslinger G, Tegeder I.

    Clin Chem. 2007 Jun;53(6):1010-5. Epub 2007 Mar 15.PMID: 17363416 [PubMed - indexed for MEDLINE]Related articlesFree article

    3.

    Lack of influence of GTP cyclohydrolase gene (GCH1) variations on pain sensitivity in humans.

    Kim H, Dionne RA.

    Mol Pain. 2007 Mar 7;3:6.PMID: 17343757 [PubMed - indexed for MEDLINE]Related articlesFree article

    4.

    Reduced hyperalgesia in homozygous carriers of a GTP cyclohydrolase 1 haplotype.

    Tegeder I, Adolph J, Schmidt H, Woolf CJ, Geisslinger G, Lötsch J.

    Eur J Pain. 2008 Nov;12(8):1069-77. Epub 2008 Apr 18.PMID: 18374612 [PubMed - indexed for MEDLINE]Related articles

    5.

    Clinical genetics of functionally mild non-coding GTP cyclohydrolase 1 (GCH1) polymorphisms modulating pain and cardiovascular risk.

    Doehring A, Antoniades C, Channon KM, Tegeder I, Lötsch J.

    Mutat Res. 2008 Sep-Oct;659(3):195-201. Epub 2008 Apr 26. Review.PMID: 18515178 [PubMed - indexed for MEDLINE]Related articles

    6.

    Does the pain-protective GTP cyclohydrolase haplotype significantly alter the pattern or severity of pain in humans with chronic pancreatitis?

    Lazarev M, Lamb J, Barmada MM, Dai F, Anderson MA, Max MB, Whitcomb DC.

    Mol Pain. 2008 Nov 17;4:58.PMID: 19014702 [PubMed - indexed for MEDLINE]Related articlesFree article

    7.

    Discovery of common human genetic variants of GTP cyclohydrolase 1 (GCH1) governing nitric oxide, autonomic activity, and cardiovascular risk.

    Zhang L, Rao F, Zhang K, Khandrika S, Das M, Vaingankar SM, Bao X, Rana BK, Smith DW, Wessel J, Salem RM, Rodriguez-Flores JL, Mahata SK, Schork NJ, Ziegler MG, O'Connor DT.

    J Clin Invest. 2007 Sep;117(9):2658-71.PMID: 17717598 [PubMed - indexed for MEDLINE]Related articlesFree article

    8.

    Do genetic predictors of pain sensitivity associate with persistent widespread pain?

    Holliday KL, Nicholl BI, Macfarlane GJ, Thomson W, Davies KA, McBeth J.

    Mol Pain. 2009 Sep 23;5:56.PMID: 19775452 [PubMed - in process]Related articlesFree article

    9.

    Cross-sectional assessment of the consequences of a GTP cyclohydrolase 1 haplotype for specialized tertiary outpatient pain care.

    Doehring A, Freynhagen R, Griessinger N, Zimmermann M, Sittl R, Hentig N, Geisslinger G, Lötsch J.

    Clin J Pain. 2009 Nov-Dec;25(9):781-5.PMID: 19851158 [PubMed - in process]Related articles

    10.

    GCH1 haplotype determines vascular and plasma biopterin availability in coronary artery disease effects on vascular superoxide production and endothelial function.

    Antoniades C, Shirodaria C, Van Assche T, Cunnington C, Tegeder I, Lötsch J, Guzik TJ, Leeson P, Diesch J, Tousoulis D, Stefanadis C, Costigan M, Woolf CJ, Alp NJ, Channon KM.

    J Am Coll Cardiol. 2008 Jul 8;52(2):158-65.PMID: 18598896 [PubMed - indexed for MEDLINE]Related articlesFree article

    11.

    Adaptive copy number evolution in malaria parasites.

    Nair S, Miller B, Barends M, Jaidee A, Patel J, Mayxay M, Newton P, Nosten F, Ferdig MT, Anderson TJ.

    PLoS Genet. 2008 Oct;4(10):e1000243. Epub 2008 Oct 31.PMID: 18974876 [PubMed - indexed for MEDLINE]Related articlesFree article

    12.

    GTP cyclohydrolase and tetrahydrobiopterin regulate pain sensitivity and persistence.

    Tegeder I, Costigan M, Griffin RS, Abele A, Belfer I, Schmidt H, Ehnert C, Nejim J, Marian C, Scholz J, Wu T, Allchorne A, Diatchenko L, Binshtok AM, Goldman D, Adolph J, Sama S, Atlas SJ, Carlezon WA, Parsegian A, Lötsch J, Fillingim RB, Maixner W, Geisslinger G, Max MB, Woolf CJ.

    Nat Med. 2006 Nov;12(11):1269-77. Epub 2006 Oct 22.PMID: 17057711 [PubMed - indexed for MEDLINE]Related articles

    13.

    Decrease in GTP cyclohydrolase I gene expression caused by inactivation of one allele in hereditary progressive dystonia with marked diurnal fluctuation.

    Inagaki H, Ohye T, Suzuki T, Segawa M, Nomura Y, Nagatsu T, Ichinose H.

    Biochem Biophys Res Commun. 1999 Jul 14;260(3):747-51.PMID: 10403837 [PubMed - indexed for MEDLINE]Related articles

    14.

    [Genetic polymorphisms and human sensitivity to pain and opioids]

    Nishizawa D, Nagashima M, Satoh Y, Tagami M, Ikeda K.

    Masui. 2009 Sep;58(9):1093-101. Review. Japanese. PMID: 19764431 [PubMed - indexed for MEDLINE]Related articles

    15.

    Predisposition of genetic disease by modestly decreased expression of GCH1 mutant allele.

    Kim YS, Choi YB, Lee JH, Yang SH, Cho JH, Shin CH, Lee SD, Paik MK, Hong KM.

    Exp Mol Med. 2008 Jun 30;40(3):271-5.PMID: 18587264 [PubMed - indexed for MEDLINE]Related articlesFree article

    16.

    Novel mutations in the guanosine triphosphate cyclohydrolase 1 gene associated with DYT5 dystonia.

    Ohta E, Funayama M, Ichinose H, Toyoshima I, Urano F, Matsuo M, Tomoko N, Yukihiko K, Yoshino S, Yokoyama H, Shimazu H, Maeda K, Hasegawa K, Obata F.

    Arch Neurol. 2006 Nov;63(11):1605-10.PMID: 17101830 [PubMed - indexed for MEDLINE]Related articlesFree article

    17.

    Dopa-responsive dystonia due to a large deletion in the GTP cyclohydrolase I gene.

    Furukawa Y, Guttman M, Sparagana SP, Trugman JM, Hyland K, Wyatt P, Lang AE, Rouleau GA, Shimadzu M, Kish SJ.

    Ann Neurol. 2000 Apr;47(4):517-20.PMID: 10762165 [PubMed - indexed for MEDLINE]Related articles

    18.

    Reduced lymphoblast neopterin detects GTP cyclohydrolase dysfunction in dopa-responsive dystonia.

    Bezin L, Nygaard TG, Neville JD, Shen H, Levine RA.

    Neurology. 1998 Apr;50(4):1021-7.PMID: 9566389 [PubMed - indexed for MEDLINE]Related articles

    19.

    The pain protective haplotype: introducing the modern genetic test.

    Klein RD.

    Clin Chem. 2007 Jun;53(6):1007-9. No abstract available. PMID: 17517586 [PubMed - indexed for MEDLINE]Related articlesFree article

    20.

    Study of a Swiss dopa-responsive dystonia family with a deletion in GCH1: redefining DYT14 as DYT5.

    Wider C, Melquist S, Hauf M, Solida A, Cobb SA, Kachergus JM, Gass J, Coon KD, Baker M, Cannon A, Stephan DA, Schorderet DF, Ghika J, Burkhard PR, Kapatos G, Hutton M, Farrer MJ, Wszolek ZK, Vingerhoets FJ.

    Neurology. 2008 Apr 15;70(16 Pt 2):1377-83. Epub 2007 Sep 5.PMID: 17804835 [PubMed - indexed for MEDLINE]Related articlesFree article

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