PubMed

Muscle-derived angiopoietin-like protein 4 is induced by fatty acids via peroxisome proliferator-activated receptor (PPAR)-delta and is of metabolic relevance in humans.

Staiger H, Haas C, Machann J, Werner R, Weisser M, Schick F, Machicao F, Stefan N, Fritsche A, Häring HU.

Diabetes. 2009 Mar;58(3):579-89. Epub 2008 Dec 15.PMID: 19074989 [PubMed - indexed for MEDLINE]Related articlesFree article

Suppression of plasma free fatty acids upregulates peroxisome proliferator-activated receptor (PPAR) alpha and delta and PPAR coactivator 1alpha in human skeletal muscle, but not lipid regulatory genes.

Watt MJ, Southgate RJ, Holmes AG, Febbraio MA.

J Mol Endocrinol. 2004 Oct;33(2):533-44.PMID: 15525607 [PubMed - indexed for MEDLINE]Related articlesFree article

Fatty acid homeostasis and induction of lipid regulatory genes in skeletal muscles of peroxisome proliferator-activated receptor (PPAR) alpha knock-out mice. Evidence for compensatory regulation by PPAR delta.

Muoio DM, MacLean PS, Lang DB, Li S, Houmard JA, Way JM, Winegar DA, Corton JC, Dohm GL, Kraus WE.

J Biol Chem. 2002 Jul 19;277(29):26089-97. Epub 2002 May 6.PMID: 12118038 [PubMed - indexed for MEDLINE]Related articlesFree article

Effect of medium- and long-chain fatty acid diets on PPAR and SREBP-1 expression and glucose homeostasis in ACBP-overexpressing transgenic rats.

Oikari S, Ahtialansaari T, Huotari A, Kiehne K, Fölsch UR, Wolffram S, Jänne J, Alhonen L, Herzig KH.

Acta Physiol (Oxf). 2008 Sep;194(1):57-65. Epub 2008 Apr 3.PMID: 18394026 [PubMed - indexed for MEDLINE]Related articles

Direct activation of glucose transport in primary human myotubes after activation of peroxisome proliferator-activated receptor delta.

Krämer DK, Al-Khalili L, Perrini S, Skogsberg J, Wretenberg P, Kannisto K, Wallberg-Henriksson H, Ehrenborg E, Zierath JR, Krook A.

Diabetes. 2005 Apr;54(4):1157-63.PMID: 15793256 [PubMed - indexed for MEDLINE]Related articlesFree article

Regulation of angiopoietin-like protein 4/fasting-induced adipose factor (Angptl4/FIAF) expression in mouse white adipose tissue and 3T3-L1 adipocytes.

Dutton S, Trayhurn P.

Br J Nutr. 2008 Jul;100(1):18-26. Epub 2007 Dec 17.PMID: 18081944 [PubMed - indexed for MEDLINE]Related articles

Peroxisome proliferator-activated receptor (PPAR)-alpha agonism prevents the onset of type 2 diabetes in Zucker diabetic fatty rats: A comparison with PPAR gamma agonism.

Bergeron R, Yao J, Woods JW, Zycband EI, Liu C, Li Z, Adams A, Berger JP, Zhang BB, Moller DE, Doebber TW.

Endocrinology. 2006 Sep;147(9):4252-62. Epub 2006 May 25.PMID: 16728496 [PubMed - indexed for MEDLINE]Related articlesFree article

Expression of genes involved in lipid metabolism correlate with peroxisome proliferator-activated receptor gamma expression in human skeletal muscle.

Lapsys NM, Kriketos AD, Lim-Fraser M, Poynten AM, Lowy A, Furler SM, Chisholm DJ, Cooney GJ.

J Clin Endocrinol Metab. 2000 Nov;85(11):4293-7.PMID: 11095470 [PubMed - indexed for MEDLINE]Related articlesFree article

Improvement of insulin sensitivity after peroxisome proliferator-activated receptor-alpha agonist treatment is accompanied by paradoxical increase of circulating resistin levels.

Haluzik MM, Lacinova Z, Dolinkova M, Haluzikova D, Housa D, Horinek A, Vernerova Z, Kumstyrova T, Haluzik M.

Endocrinology. 2006 Sep;147(9):4517-24. Epub 2006 Jun 1.PMID: 16740970 [PubMed - indexed for MEDLINE]Related articlesFree article

Differential expression of peroxisomal proliferator activated receptors alpha and delta in skeletal muscle in response to changes in diet and exercise.

Kannisto K, Chibalin A, Glinghammar B, Zierath JR, Hamsten A, Ehrenborg E.

Int J Mol Med. 2006 Jan;17(1):45-52.PMID: 16328010 [PubMed - indexed for MEDLINE]Related articles

The direct peroxisome proliferator-activated receptor target fasting-induced adipose factor (FIAF/PGAR/ANGPTL4) is present in blood plasma as a truncated protein that is increased by fenofibrate treatment.

Mandard S, Zandbergen F, Tan NS, Escher P, Patsouris D, Koenig W, Kleemann R, Bakker A, Veenman F, Wahli W, Müller M, Kersten S.

J Biol Chem. 2004 Aug 13;279(33):34411-20. Epub 2004 Jun 9.PMID: 15190076 [PubMed - indexed for MEDLINE]Related articlesFree article

Saturated, but not n-6 polyunsaturated, fatty acids induce insulin resistance: role of intramuscular accumulation of lipid metabolites.

Lee JS, Pinnamaneni SK, Eo SJ, Cho IH, Pyo JH, Kim CK, Sinclair AJ, Febbraio MA, Watt MJ.

J Appl Physiol. 2006 May;100(5):1467-74. Epub 2005 Dec 15.PMID: 16357064 [PubMed - indexed for MEDLINE]Related articlesFree article

Effect of saponins from Helicteres isora on lipid and glucose metabolism regulating genes expression.

Bhavsar SK, Singh S, Giri S, Jain MR, Santani DD.

J Ethnopharmacol. 2009 Jul 30;124(3):426-33. Epub 2009 Jun 6.PMID: 19505560 [PubMed - indexed for MEDLINE]Related articles

Regulatory role of peroxisome proliferator-activated receptor delta (PPAR delta) in muscle metabolism. A new target for metabolic syndrome treatment?

Grimaldi PA.

Biochimie. 2005 Jan;87(1):5-8. Review.PMID: 15733729 [PubMed - indexed for MEDLINE]Related articles

Fasting-induced increases in aquaporin 7 and adipose triglyceride lipase mRNA expression in adipose tissue are attenuated by peroxisome proliferator-activated receptor alpha deficiency.

Walker CG, Holness MJ, Gibbons GF, Sugden MC.

Int J Obes (Lond). 2007 Jul;31(7):1165-71. Epub 2007 Jan 23.PMID: 17245390 [PubMed - indexed for MEDLINE]Related articles

Angiopoietin-like protein 4 decreases blood glucose and improves glucose tolerance but induces hyperlipidemia and hepatic steatosis in mice.

Xu A, Lam MC, Chan KW, Wang Y, Zhang J, Hoo RL, Xu JY, Chen B, Chow WS, Tso AW, Lam KS.

Proc Natl Acad Sci U S A. 2005 Apr 26;102(17):6086-91. Epub 2005 Apr 18.PMID: 15837923 [PubMed - indexed for MEDLINE]Related articlesFree article

Isomer-specific antidiabetic properties of conjugated linoleic acid. Improved glucose tolerance, skeletal muscle insulin action, and UCP-2 gene expression.

Ryder JW, Portocarrero CP, Song XM, Cui L, Yu M, Combatsiaris T, Galuska D, Bauman DE, Barbano DM, Charron MJ, Zierath JR, Houseknecht KL.

Diabetes. 2001 May;50(5):1149-57.PMID: 11334420 [PubMed - indexed for MEDLINE]Related articlesFree article

Preferential channeling of energy fuels toward fat rather than muscle during high free fatty acid availability in rats.

Fabris R, Nisoli E, Lombardi AM, Tonello C, Serra R, Granzotto M, Cusin I, Rohner-Jeanrenaud F, Federspil G, Carruba MO, Vettor R.

Diabetes. 2001 Mar;50(3):601-8.PMID: 11246880 [PubMed - indexed for MEDLINE]Related articlesFree article

Lipids, lipoproteins, and peroxisome proliferator activated receptor-delta.

Sprecher DL.

Am J Cardiol. 2007 Dec 3;100(11 A):n20-4. Review.PMID: 18047848 [PubMed - indexed for MEDLINE]Related articles

Differential regulation and properties of angiopoietin-like proteins 3 and 4.

Ge H, Cha JY, Gopal H, Harp C, Yu X, Repa JJ, Li C.

J Lipid Res. 2005 Jul;46(7):1484-90. Epub 2005 May 1.PMID: 15863837 [PubMed - indexed for MEDLINE]Related articlesFree article