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    Results: 1 to 20 of 147

    1.

    Overexpression of carnitine palmitoyltransferase-1 in skeletal muscle is sufficient to enhance fatty acid oxidation and improve high-fat diet-induced insulin resistance.

    Bruce CR, Hoy AJ, Turner N, Watt MJ, Allen TL, Carpenter K, Cooney GJ, Febbraio MA, Kraegen EW.

    Diabetes. 2009 Mar;58(3):550-8. Epub 2008 Dec 10.PMID: 19073774 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    Overexpression of carnitine palmitoyltransferase I in skeletal muscle in vivo increases fatty acid oxidation and reduces triacylglycerol esterification.

    Bruce CR, Brolin C, Turner N, Cleasby ME, van der Leij FR, Cooney GJ, Kraegen EW.

    Am J Physiol Endocrinol Metab. 2007 Apr;292(4):E1231-7. Epub 2006 Dec 19.PMID: 17179390 [PubMed - indexed for MEDLINE]Related articlesFree article

    3.

    Excess lipid availability increases mitochondrial fatty acid oxidative capacity in muscle: evidence against a role for reduced fatty acid oxidation in lipid-induced insulin resistance in rodents.

    Turner N, Bruce CR, Beale SM, Hoehn KL, So T, Rolph MS, Cooney GJ.

    Diabetes. 2007 Aug;56(8):2085-92. Epub 2007 May 22.PMID: 17519422 [PubMed - indexed for MEDLINE]Related articlesFree article

    4.

    Heat treatment improves glucose tolerance and prevents skeletal muscle insulin resistance in rats fed a high-fat diet.

    Gupte AA, Bomhoff GL, Swerdlow RH, Geiger PC.

    Diabetes. 2009 Mar;58(3):567-78. Epub 2008 Dec 10.PMID: 19073766 [PubMed - indexed for MEDLINE]Related articlesFree article

    5.

    Increased beta-oxidation in muscle cells enhances insulin-stimulated glucose metabolism and protects against fatty acid-induced insulin resistance despite intramyocellular lipid accumulation.

    Perdomo G, Commerford SR, Richard AM, Adams SH, Corkey BE, O'Doherty RM, Brown NF.

    J Biol Chem. 2004 Jun 25;279(26):27177-86. Epub 2004 Apr 22.PMID: 15105415 [PubMed - indexed for MEDLINE]Related articlesFree article

    6.

    Mechanisms of liver and muscle insulin resistance induced by chronic high-fat feeding.

    Oakes ND, Cooney GJ, Camilleri S, Chisholm DJ, Kraegen EW.

    Diabetes. 1997 Nov;46(11):1768-74.PMID: 9356024 [PubMed - indexed for MEDLINE]Related articles

    7.

    Crocetin improves the insulin resistance induced by high-fat diet in rats.

    Sheng L, Qian Z, Shi Y, Yang L, Xi L, Zhao B, Xu X, Ji H.

    Br J Pharmacol. 2008 Jul;154(5):1016-24. Epub 2008 May 12.PMID: 18469847 [PubMed - indexed for MEDLINE]Related articlesFree article

    8.

    Medium-chain fatty acids ameliorate insulin resistance caused by high-fat diets in rats.

    Wein S, Wolffram S, Schrezenmeir J, Gasperiková D, Klimes I, Seböková E.

    Diabetes Metab Res Rev. 2009 Feb;25(2):185-94.PMID: 19219861 [PubMed - indexed for MEDLINE]Related articles

    9.

    [The mechanism of and relationship between lipid metabolism genes expression and insulin resistance in high fat-fed mice]

    Bai XP, Li HL, Yang WY, Xiao JZ, Wang B, Du RQ, Lou DJ.

    Zhonghua Nei Ke Za Zhi. 2007 Sep;46(9):751-4. Chinese. PMID: 18028806 [PubMed - indexed for MEDLINE]Related articles

    10.

    Diet-induced muscle insulin resistance in rats is ameliorated by acute dietary lipid withdrawal or a single bout of exercise: parallel relationship between insulin stimulation of glucose uptake and suppression of long-chain fatty acyl-CoA.

    Oakes ND, Bell KS, Furler SM, Camilleri S, Saha AK, Ruderman NB, Chisholm DJ, Kraegen EW.

    Diabetes. 1997 Dec;46(12):2022-8.PMID: 9392490 [PubMed - indexed for MEDLINE]Related articles

    11.

    Saturated, but not n-6 polyunsaturated, fatty acids induce insulin resistance: role of intramuscular accumulation of lipid metabolites.

    Lee JS, Pinnamaneni SK, Eo SJ, Cho IH, Pyo JH, Kim CK, Sinclair AJ, Febbraio MA, Watt MJ.

    J Appl Physiol. 2006 May;100(5):1467-74. Epub 2005 Dec 15.PMID: 16357064 [PubMed - indexed for MEDLINE]Related articlesFree article

    12.

    Enhanced susceptibility of Cpt1c knockout mice to glucose intolerance induced by a high-fat diet involves elevated hepatic gluconeogenesis and decreased skeletal muscle glucose uptake.

    Gao XF, Chen W, Kong XP, Xu AM, Wang ZG, Sweeney G, Wu D.

    Diabetologia. 2009 May;52(5):912-20. Epub 2009 Feb 18.PMID: 19224198 [PubMed - indexed for MEDLINE]Related articles

    13.

    The long-term regulation of skeletal muscle pyruvate dehydrogenase kinase by dietary lipid is dependent on fatty acid composition.

    Fryer LG, Orfali KA, Holness MJ, Saggerson ED, Sugden MC.

    Eur J Biochem. 1995 May 1;229(3):741-8.PMID: 7758471 [PubMed - indexed for MEDLINE]Related articlesFree article

    14.

    Comparison of the extrapancreatic action of gamma-linolenic acid and n-3 PUFAs in the high fat diet-induced insulin resistance [corrected].

    Simoncíkova P, Wein S, Gasperikova D, Ukropec J, Certik M, Klimes I, Sebokova E.

    Endocr Regul. 2002 Nov;36(4):143-9. Erratum in: Endocr Regul. 2003 Mar;37(1):20. PMID: 12466014 [PubMed - indexed for MEDLINE]Related articlesFree article

    15.

    Mitochondrial overload and incomplete fatty acid oxidation contribute to skeletal muscle insulin resistance.

    Koves TR, Ussher JR, Noland RC, Slentz D, Mosedale M, Ilkayeva O, Bain J, Stevens R, Dyck JR, Newgard CB, Lopaschuk GD, Muoio DM.

    Cell Metab. 2008 Jan;7(1):45-56.PMID: 18177724 [PubMed - indexed for MEDLINE]Related articles

    16.

    Prolonged inhibition of muscle carnitine palmitoyltransferase-1 promotes intramyocellular lipid accumulation and insulin resistance in rats.

    Dobbins RL, Szczepaniak LS, Bentley B, Esser V, Myhill J, McGarry JD.

    Diabetes. 2001 Jan;50(1):123-30.PMID: 11147777 [PubMed - indexed for MEDLINE]Related articlesFree article

    17.

    Increased efficiency of fatty acid uptake contributes to lipid accumulation in skeletal muscle of high fat-fed insulin-resistant rats.

    Hegarty BD, Cooney GJ, Kraegen EW, Furler SM.

    Diabetes. 2002 May;51(5):1477-84.PMID: 11978645 [PubMed - indexed for MEDLINE]Related articlesFree article

    18.

    Dietary soya protein intake and exercise training have an additive effect on skeletal muscle fatty acid oxidation enzyme activities and mRNA levels in rats.

    Morifuji M, Sanbongi C, Sugiura K.

    Br J Nutr. 2006 Sep;96(3):469-75.PMID: 16925851 [PubMed - indexed for MEDLINE]Related articles

    19.

    Malonyl-CoA and the regulation of fatty acid oxidation in soleus muscle.

    Alam N, Saggerson ED.

    Biochem J. 1998 Aug 15;334 ( Pt 1):233-41.PMID: 9693125 [PubMed - indexed for MEDLINE]Related articlesFree article

    20.

    Modest PGC-1alpha overexpression in muscle in vivo is sufficient to increase insulin sensitivity and palmitate oxidation in subsarcolemmal, not intermyofibrillar, mitochondria.

    Benton CR, Nickerson JG, Lally J, Han XX, Holloway GP, Glatz JF, Luiken JJ, Graham TE, Heikkila JJ, Bonen A.

    J Biol Chem. 2008 Feb 15;283(7):4228-40. Epub 2007 Dec 12.PMID: 18079123 [PubMed - indexed for MEDLINE]Related articlesFree article

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