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    Results: 1 to 20 of 121

    1.

    Variants near MC4R are associated with obesity and influence obesity-related quantitative traits in a population of middle-aged people: studies of 14,940 Danes.

    Zobel DP, Andreasen CH, Grarup N, Eiberg H, Sørensen TI, Sandbaek A, Lauritzen T, Borch-Johnsen K, Jørgensen T, Pedersen O, Hansen T.

    Diabetes. 2009 Mar;58(3):757-64. Epub 2008 Dec 10.PMID: 19073769 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    Common variants near MC4R are associated with fat mass, weight and risk of obesity.

    Loos RJ, Lindgren CM, Li S, Wheeler E, Zhao JH, Prokopenko I, Inouye M, Freathy RM, Attwood AP, Beckmann JS, Berndt SI; Prostate, Lung, Colorectal, and Ovarian (PLCO) Cancer Screening Trial, Jacobs KB, Chanock SJ, Hayes RB, Bergmann S, Bennett AJ, Bingham SA, Bochud M, Brown M, Cauchi S, Connell JM, Cooper C, Smith GD, Day I, Dina C, De S, Dermitzakis ET, Doney AS, Elliott KS, Elliott P, Evans DM, Sadaf Farooqi I, Froguel P, Ghori J, Groves CJ, Gwilliam R, Hadley D, Hall AS, Hattersley AT, Hebebrand J, Heid IM; KORA, Lamina C, Gieger C, Illig T, Meitinger T, Wichmann HE, Herrera B, Hinney A, Hunt SE, Jarvelin MR, Johnson T, Jolley JD, Karpe F, Keniry A, Khaw KT, Luben RN, Mangino M, Marchini J, McArdle WL, McGinnis R, Meyre D, Munroe PB, Morris AD, Ness AR, Neville MJ, Nica AC, Ong KK, O'Rahilly S, Owen KR, Palmer CN, Papadakis K, Potter S, Pouta A, Qi L; Nurses' Health Study, Randall JC, Rayner NW, Ring SM, Sandhu MS, Scherag A, Sims MA, Song K, Soranzo N, Speliotes EK; Diabetes Genetics Initiative, Syddall HE, Teichmann SA, Timpson NJ, Tobias JH, Uda M; SardiNIA Study, Vogel CI, Wallace C, Waterworth DM, Weedon MN; Wellcome Trust Case Control Consortium, Willer CJ; FUSION, Wraight, Yuan X, Zeggini E, Hirschhorn JN, Strachan DP, Ouwehand WH, Caulfield MJ, Samani NJ, Frayling TM, Vollenweider P, Waeber G, Mooser V, Deloukas P, McCarthy MI, Wareham NJ, Barroso I, Jacobs KB, Chanock SJ, Hayes RB, Lamina C, Gieger C, Illig T, Meitinger T, Wichmann HE, Kraft P, Hankinson SE, Hunter DJ, Hu FB, Lyon HN, Voight BF, Ridderstrale M, Groop L, Scheet P, Sanna S, Abecasis GR, Albai G, Nagaraja R, Schlessinger D, Jackson AU, Tuomilehto J, Collins FS, Boehnke M, Mohlke KL.

    Nat Genet. 2008 Jun;40(6):768-75. Epub 2008 May 4.PMID: 18454148 [PubMed - indexed for MEDLINE]Related articlesFree article

    3.

    Combined effects of MC4R and FTO common genetic variants on obesity in European general populations.

    Cauchi S, Stutzmann F, Cavalcanti-Proença C, Durand E, Pouta A, Hartikainen AL, Marre M, Vol S, Tammelin T, Laitinen J, Gonzalez-Izquierdo A, Blakemore AI, Elliott P, Meyre D, Balkau B, Järvelin MR, Froguel P.

    J Mol Med. 2009 May;87(5):537-46. Epub 2009 Mar 3.PMID: 19255736 [PubMed - indexed for MEDLINE]Related articles

    4.

    Studies of CTNNBL1 and FDFT1 variants and measures of obesity: analyses of quantitative traits and case-control studies in 18,014 Danes.

    Andreasen CH, Mogensen MS, Borch-Johnsen K, Sandbaek A, Lauritzen T, Almind K, Hansen L, Jørgensen T, Pedersen O, Hansen T.

    BMC Med Genet. 2009 Feb 26;10:17.PMID: 19245693 [PubMed - indexed for MEDLINE]Related articlesFree article

    5.

    The common obesity variant near MC4R gene is associated with higher intakes of total energy and dietary fat, weight change and diabetes risk in women.

    Qi L, Kraft P, Hunter DJ, Hu FB.

    Hum Mol Genet. 2008 Nov 15;17(22):3502-8. Epub 2008 Aug 12.PMID: 18697794 [PubMed - indexed for MEDLINE]Related articlesFree article

    6.

    Variation in the gene encoding Krüppel-like factor 7 influences body fat: studies of 14 818 Danes.

    Zobel DP, Andreasen CH, Burgdorf KS, Andersson EA, Sandbaek A, Lauritzen T, Borch-Johnsen K, Jørgensen T, Maeda S, Nakamura Y, Eiberg H, Pederse O, Hansen T.

    Eur J Endocrinol. 2009 Apr;160(4):603-9. Epub 2009 Jan 15.PMID: 19147600 [PubMed - indexed for MEDLINE]Related articles

    7.

    Common variants near MC4R in relation to body fat, body fat distribution, metabolic traits and energy expenditure.

    Kring SI, Holst C, Toubro S, Astrup A, Hansen T, Pedersen O, Sørensen TI.

    Int J Obes (Lond). 2009 Oct 20. [Epub ahead of print]PMID: 19844209 [PubMed - as supplied by publisher]Related articles

    8.

    Genome-wide association scan shows genetic variants in the FTO gene are associated with obesity-related traits.

    Scuteri A, Sanna S, Chen WM, Uda M, Albai G, Strait J, Najjar S, Nagaraja R, Orrú M, Usala G, Dei M, Lai S, Maschio A, Busonero F, Mulas A, Ehret GB, Fink AA, Weder AB, Cooper RS, Galan P, Chakravarti A, Schlessinger D, Cao A, Lakatta E, Abecasis GR.

    PLoS Genet. 2007 Jul;3(7):e115.PMID: 17658951 [PubMed - indexed for MEDLINE]Related articlesFree article

    9.

    Common genetic variation near MC4R is associated with waist circumference and insulin resistance.

    Chambers JC, Elliott P, Zabaneh D, Zhang W, Li Y, Froguel P, Balding D, Scott J, Kooner JS.

    Nat Genet. 2008 Jun;40(6):716-8. Epub 2008 May 4.PMID: 18454146 [PubMed - indexed for MEDLINE]Related articles

    10.

    Studies of the relationship between the ENPP1 K121Q polymorphism and type 2 diabetes, insulin resistance and obesity in 7,333 Danish white subjects.

    Grarup N, Urhammer SA, Ek J, Albrechtsen A, Glümer C, Borch-Johnsen K, Jørgensen T, Hansen T, Pedersen O.

    Diabetologia. 2006 Sep;49(9):2097-104. Epub 2006 Jul 25.PMID: 16865358 [PubMed - indexed for MEDLINE]Related articles

    11.

    Low physical activity accentuates the effect of the FTO rs9939609 polymorphism on body fat accumulation.

    Andreasen CH, Stender-Petersen KL, Mogensen MS, Torekov SS, Wegner L, Andersen G, Nielsen AL, Albrechtsen A, Borch-Johnsen K, Rasmussen SS, Clausen JO, Sandbaek A, Lauritzen T, Hansen L, Jørgensen T, Pedersen O, Hansen T.

    Diabetes. 2008 Jan;57(1):95-101. Epub 2007 Oct 17.PMID: 17942823 [PubMed - indexed for MEDLINE]Related articlesFree article

    12.

    Association of the 103I MC4R allele with decreased body mass in 7937 participants of two population based surveys.

    Heid IM, Vollmert C, Hinney A, Döring A, Geller F, Löwel H, Wichmann HE, Illig T, Hebebrand J, Kronenberg F; KORA Group.

    J Med Genet. 2005 Apr;42(4):e21.PMID: 15805150 [PubMed - indexed for MEDLINE]Related articlesFree article

    13.

    Lack of association between PKLR rs3020781 and NOS1AP rs7538490 and type 2 diabetes, overweight, obesity and related metabolic phenotypes in a Danish large-scale study: case-control studies and analyses of quantitative traits.

    Andreasen CH, Mogensen MS, Borch-Johnsen K, Sandbaek A, Lauritzen T, Almind K, Hansen L, Jørgensen T, Pedersen O, Hansen T.

    BMC Med Genet. 2008 Dec 26;9:118.PMID: 19111066 [PubMed - indexed for MEDLINE]Related articlesFree article

    14.

    Association testing of novel type 2 diabetes risk alleles in the JAZF1, CDC123/CAMK1D, TSPAN8, THADA, ADAMTS9, and NOTCH2 loci with insulin release, insulin sensitivity, and obesity in a population-based sample of 4,516 glucose-tolerant middle-aged Danes.

    Grarup N, Andersen G, Krarup NT, Albrechtsen A, Schmitz O, Jørgensen T, Borch-Johnsen K, Hansen T, Pedersen O.

    Diabetes. 2008 Sep;57(9):2534-40. Epub 2008 Jun 20.PMID: 18567820 [PubMed - indexed for MEDLINE]Related articlesFree article

    15.

    Non-replication of genome-wide based associations between common variants in INSIG2 and PFKP and obesity in studies of 18,014 Danes.

    Andreasen CH, Mogensen MS, Borch-Johnsen K, Sandbaek A, Lauritzen T, Sørensen TI, Hansen L, Almind K, Jørgensen T, Pedersen O, Hansen T.

    PLoS One. 2008 Aug 6;3(8):e2872.PMID: 18682847 [PubMed - indexed for MEDLINE]Related articlesFree article

    16.

    Common variation in the FTO gene alters diabetes-related metabolic traits to the extent expected given its effect on BMI.

    Freathy RM, Timpson NJ, Lawlor DA, Pouta A, Ben-Shlomo Y, Ruokonen A, Ebrahim S, Shields B, Zeggini E, Weedon MN, Lindgren CM, Lango H, Melzer D, Ferrucci L, Paolisso G, Neville MJ, Karpe F, Palmer CN, Morris AD, Elliott P, Jarvelin MR, Smith GD, McCarthy MI, Hattersley AT, Frayling TM.

    Diabetes. 2008 May;57(5):1419-26. Epub 2008 Mar 17.PMID: 18346983 [PubMed - indexed for MEDLINE]Related articlesFree article

    17.

    Common genetic variants at the MC4R locus are associated with obesity, but not with dietary energy intake or colorectal cancer in the Scottish population.

    Tenesa A, Campbell H, Theodoratou E, Dunlop L, Cetnarskyj R, Farrington SM, Dunlop MG.

    Int J Obes (Lond). 2009 Feb;33(2):284-8. Epub 2008 Dec 9.PMID: 19050674 [PubMed - indexed for MEDLINE]Related articles

    18.

    Replication of Association Between a Common Variant Near Melanocortin-4 Receptor Gene and Obesity-related Traits in Asian Sikhs.

    Been LF, Nath SK, Ralhan SK, Wander GS, Mehra NK, Singh J, Mulvihill JJ, Sanghera DK.

    Obesity (Silver Spring). 2009 Aug 13. [Epub ahead of print]PMID: 19680233 [PubMed - as supplied by publisher]Related articles

    19.

    [Prevalence of melanocortin 4 receptor (MC4R) mutations and polymorphismsin consecutively ascertained obese children and adolescents from a pediatric health care utilization population]

    Zakel UA, Wudy SA, Heinzel-Gutenbrunner M, Görg T, Schäfer H, Gortner L, Blum WF, Hebebrand J, Hinney A.

    Klin Padiatr. 2005 Jul-Aug;217(4):244-9. German. PMID: 16032553 [PubMed - indexed for MEDLINE]Related articles

    20.

    [Association between melanocortin 4 receptor gene polymorphisms and obesity]

    Zhang R, Jia WP, Hu C, Wang CR, Fang QC, Bao YQ, Lu JX, Ma XJ, Xu J, Lu HJ, Xiang KS.

    Zhonghua Yi Xue Za Zhi. 2007 Jan 9;87(2):96-9. Chinese. PMID: 17418015 [PubMed - indexed for MEDLINE]Related articles

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