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    Results: 1 to 20 of 137

    1.

    Mitochondrial reactive oxygen species are obligatory signals for glucose-induced insulin secretion.

    Leloup C, Tourrel-Cuzin C, Magnan C, Karaca M, Castel J, Carneiro L, Colombani AL, Ktorza A, Casteilla L, Pénicaud L.

    Diabetes. 2009 Mar;58(3):673-81. Epub 2008 Dec 10.PMID: 19073765 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    Mitochondrial reactive oxygen species are required for hypothalamic glucose sensing.

    Leloup C, Magnan C, Benani A, Bonnet E, Alquier T, Offer G, Carriere A, Périquet A, Fernandez Y, Ktorza A, Casteilla L, Pénicaud L.

    Diabetes. 2006 Jul;55(7):2084-90.PMID: 16804079 [PubMed - indexed for MEDLINE]Related articlesFree article

    3.

    Ouabain suppresses glucose-induced mitochondrial ATP production and insulin release by generating reactive oxygen species in pancreatic islets.

    Kajikawa M, Fujimoto S, Tsuura Y, Mukai E, Takeda T, Hamamoto Y, Takehiro M, Fujita J, Yamada Y, Seino Y.

    Diabetes. 2002 Aug;51(8):2522-9.PMID: 12145166 [PubMed - indexed for MEDLINE]Related articlesFree article

    4.

    Inhibition of mitochondrial Na+-Ca2+ exchanger increases mitochondrial metabolism and potentiates glucose-stimulated insulin secretion in rat pancreatic islets.

    Lee B, Miles PD, Vargas L, Luan P, Glasco S, Kushnareva Y, Kornbrust ES, Grako KA, Wollheim CB, Maechler P, Olefsky JM, Anderson CM.

    Diabetes. 2003 Apr;52(4):965-73.PMID: 12663468 [PubMed - indexed for MEDLINE]Related articlesFree article

    5.

    Src activation generates reactive oxygen species and impairs metabolism-secretion coupling in diabetic Goto-Kakizaki and ouabain-treated rat pancreatic islets.

    Kominato R, Fujimoto S, Mukai E, Nakamura Y, Nabe K, Shimodahira M, Nishi Y, Funakoshi S, Seino Y, Inagaki N.

    Diabetologia. 2008 Jul;51(7):1226-35. Epub 2008 May 1.PMID: 18449527 [PubMed - indexed for MEDLINE]Related articles

    6.

    Glucose suppresses superoxide generation in metabolically responsive pancreatic beta cells.

    Martens GA, Cai Y, Hinke S, Stangé G, Van de Casteele M, Pipeleers D.

    J Biol Chem. 2005 May 27;280(21):20389-96. Epub 2005 Mar 17.PMID: 15774474 [PubMed - indexed for MEDLINE]Related articlesFree article

    7.

    Evidence for a role of superoxide generation in glucose-induced beta-cell dysfunction in vivo.

    Tang C, Han P, Oprescu AI, Lee SC, Gyulkhandanyan AV, Chan GN, Wheeler MB, Giacca A.

    Diabetes. 2007 Nov;56(11):2722-31. Epub 2007 Aug 6.PMID: 17682092 [PubMed - indexed for MEDLINE]Related articlesFree article

    8.

    Chronic exposure to beta-hydroxybutyrate inhibits glucose-induced insulin release from pancreatic islets by decreasing NADH contents.

    Takehiro M, Fujimoto S, Shimodahira M, Shimono D, Mukai E, Nabe K, Radu RG, Kominato R, Aramaki Y, Seino Y, Yamada Y.

    Am J Physiol Endocrinol Metab. 2005 Feb;288(2):E372-80. Epub 2004 Oct 12.PMID: 15479955 [PubMed - indexed for MEDLINE]Related articlesFree article

    9.

    Mitochondrial reactive oxygen species reduce insulin secretion by pancreatic beta-cells.

    Sakai K, Matsumoto K, Nishikawa T, Suefuji M, Nakamaru K, Hirashima Y, Kawashima J, Shirotani T, Ichinose K, Brownlee M, Araki E.

    Biochem Biophys Res Commun. 2003 Jan 3;300(1):216-22.PMID: 12480546 [PubMed - indexed for MEDLINE]Related articles

    10.

    D-Glyceraldehyde causes production of intracellular peroxide in pancreatic islets, oxidative stress, and defective beta cell function via non-mitochondrial pathways.

    Takahashi H, Tran PO, LeRoy E, Harmon JS, Tanaka Y, Robertson RP.

    J Biol Chem. 2004 Sep 3;279(36):37316-23. Epub 2004 Jun 22.PMID: 15213233 [PubMed - indexed for MEDLINE]Related articlesFree article

    11.

    Increased uncoupling protein-2 levels in beta-cells are associated with impaired glucose-stimulated insulin secretion: mechanism of action.

    Chan CB, De Leo D, Joseph JW, McQuaid TS, Ha XF, Xu F, Tsushima RG, Pennefather PS, Salapatek AM, Wheeler MB.

    Diabetes. 2001 Jun;50(6):1302-10.PMID: 11375330 [PubMed - indexed for MEDLINE]Related articlesFree article

    12.

    Sodium palmitate induces partial mitochondrial uncoupling and reactive oxygen species in rat pancreatic islets in vitro.

    Carlsson C, Borg LA, Welsh N.

    Endocrinology. 1999 Aug;140(8):3422-8.PMID: 10433196 [PubMed - indexed for MEDLINE]Related articlesFree article

    13.

    HIV-1 protease inhibitor induced oxidative stress suppresses glucose stimulated insulin release: protection with thymoquinone.

    Chandra S, Mondal D, Agrawal KC.

    Exp Biol Med (Maywood). 2009 Apr;234(4):442-53. Epub 2009 Feb 20.PMID: 19234050 [PubMed - indexed for MEDLINE]Related articles

    14.

    Increasing uncoupling protein-2 in pancreatic beta cells does not alter glucose-induced insulin secretion but decreases production of reactive oxygen species.

    Produit-Zengaffinen N, Davis-Lameloise N, Perreten H, Bécard D, Gjinovci A, Keller PA, Wollheim CB, Herrera P, Muzzin P, Assimacopoulos-Jeannet F.

    Diabetologia. 2007 Jan;50(1):84-93. Epub 2006 Nov 28.PMID: 17131143 [PubMed - indexed for MEDLINE]Related articles

    15.

    Reactive oxygen species amplify protein kinase C signaling in high glucose-induced fibronectin expression by human peritoneal mesothelial cells.

    Lee HB, Yu MR, Song JS, Ha H.

    Kidney Int. 2004 Apr;65(4):1170-9. Erratum in: Kidney Int. 2004 May;65(5):1989. PMID: 15086456 [PubMed - indexed for MEDLINE]Related articles

    16.

    Calcium and a mitochondrial signal interact to stimulate phosphoinositide hydrolysis and insulin secretion in rat islets.

    Kelley GG, Zawalich KC, Zawalich WS.

    Endocrinology. 1994 Apr;134(4):1648-54.PMID: 8137727 [PubMed - indexed for MEDLINE]Related articles

    17.

    Complex I-mediated reactive oxygen species generation: modulation by cytochrome c and NAD(P)+ oxidation-reduction state.

    Kushnareva Y, Murphy AN, Andreyev A.

    Biochem J. 2002 Dec 1;368(Pt 2):545-53.PMID: 12180906 [PubMed - indexed for MEDLINE]Related articlesFree article

    18.

    Stimulated Ca2+ influx raises mitochondrial free Ca2+ to supramicromolar levels in a pancreatic beta-cell line. Possible role in glucose and agonist-induced insulin secretion.

    Rutter GA, Theler JM, Murgia M, Wollheim CB, Pozzan T, Rizzuto R.

    J Biol Chem. 1993 Oct 25;268(30):22385-90.PMID: 8226749 [PubMed - indexed for MEDLINE]Related articlesFree article

    19.

    Acute overexpression of lactate dehydrogenase-A perturbs beta-cell mitochondrial metabolism and insulin secretion.

    Ainscow EK, Zhao C, Rutter GA.

    Diabetes. 2000 Jul;49(7):1149-55.PMID: 10909972 [PubMed - indexed for MEDLINE]Related articlesFree article

    20.

    Increased glucose sensitivity of stimulus-secretion coupling in islets from Psammomys obesus after diet induction of diabetes.

    Pertusa JA, Nesher R, Kaiser N, Cerasi E, Henquin JC, Jonas JC.

    Diabetes. 2002 Aug;51(8):2552-60.PMID: 12145170 [PubMed - indexed for MEDLINE]Related articlesFree article

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