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Investigation of the diurnal variation in bone resorption for optimal drug delivery and efficacy in osteoporosis with oral calcitonin.

Karsdal MA, Byrjalsen I, Riis BJ, Christiansen C.

BMC Clin Pharmacol. 2008 Dec 4;8:12.PMID: 19055791 [PubMed - indexed for MEDLINE]Related articlesFree article

Optimizing bioavailability of oral administration of small peptides through pharmacokinetic and pharmacodynamic parameters: the effect of water and timing of meal intake on oral delivery of Salmon Calcitonin.

Karsdal MA, Byrjalsen I, Riis BJ, Christiansen C.

BMC Clin Pharmacol. 2008 Sep 9;8:5.PMID: 18782439 [PubMed - indexed for MEDLINE]Related articlesFree article

Safety and efficacy of a novel salmon calcitonin (sCT) technology-based oral formulation in healthy postmenopausal women: acute and 3-month effects on biomarkers of bone turnover.

Tankó LB, Bagger YZ, Alexandersen P, Devogelaer JP, Reginster JY, Chick R, Olson M, Benmammar H, Mindeholm L, Azria M, Christiansen C.

J Bone Miner Res. 2004 Sep;19(9):1531-8. Epub 2004 Jul 26.PMID: 15312255 [PubMed - indexed for MEDLINE]Related articles

Influence of food intake on the bioavailability and efficacy of oral calcitonin.

Karsdal MA, Byrjalsen I, Azria M, Arnold M, Choi L, Riis BJ, Christiansen C.

Br J Clin Pharmacol. 2009 Apr;67(4):413-20.PMID: 19371314 [PubMed - indexed for MEDLINE]Related articles

Investigations of inter- and intraindividual relationships between exposure to oral salmon calcitonin and a surrogate marker of pharmacodynamic efficacy.

Karsdal MA, Byrjalsen I, Henriksen K, Riis BJ, Christiansen C.

Eur J Clin Pharmacol. 2009 Oct 8. [Epub ahead of print]PMID: 19813008 [PubMed - as supplied by publisher]Related articles

A randomized trial of nasal spray salmon calcitonin in men with idiopathic osteoporosis: effects on bone mineral density and bone markers.

Trovas GP, Lyritis GP, Galanos A, Raptou P, Constantelou E.

J Bone Miner Res. 2002 Mar;17(3):521-7.PMID: 11874243 [PubMed - indexed for MEDLINE]Related articles

A pharmacokinetic and pharmacodynamic comparison of synthetic and recombinant oral salmon calcitonin.

Karsdal MA, Byrjalsen I, Henriksen K, Riis BJ, Christiansen C.

J Clin Pharmacol. 2009 Feb;49(2):229-34.PMID: 19179298 [PubMed - indexed for MEDLINE]Related articles

Oral salmon calcitonin induced suppression of urinary collagen type II degradation in postmenopausal women: a new potential treatment of osteoarthritis.

Bagger YZ, Tankó LB, Alexandersen P, Karsdal MA, Olson M, Mindeholm L, Azria M, Christiansen C.

Bone. 2005 Sep;37(3):425-30.PMID: 16005273 [PubMed - indexed for MEDLINE]Related articles

The effect of oral salmon calcitonin delivered with 5-CNAC on bone and cartilage degradation in osteoarthritic patients: a 14-day randomized study.

Karsdal MA, Byrjalsen I, Henriksen K, Riis BJ, Lau EM, Arnold M, Christiansen C.

Osteoarthritis Cartilage. 2009 Sep 1. [Epub ahead of print]PMID: 19747581 [PubMed - as supplied by publisher]Related articles

Plasma type 1 collagen cross-linked C-telopeptide: a sensitive marker of acute effects of salmon calcitonin on bone resorption.

Zikán V, Stepan JJ.

Clin Chim Acta. 2002 Feb;316(1-2):63-9.PMID: 11750275 [PubMed - indexed for MEDLINE]Related articles

Strontium ranelate in osteoporosis.

Reginster JY.

Curr Pharm Des. 2002;8(21):1907-16. Review.PMID: 12171530 [PubMed - indexed for MEDLINE]Related articles

Acute effects in healthy women of oral calcium on the calcium-parathyroid axis and bone resorption as assessed by serum beta-CrossLaps.

Zikán V, Haas T, Stepan JJ.

Calcif Tissue Int. 2001 Jun;68(6):352-7. Epub 2001 May 21.PMID: 11685423 [PubMed - indexed for MEDLINE]Related articles

Morning or evening administration of nasal calcitonin? Effects on biochemical markers of bone turnover.

Schlemmer A, Ravn P, Hassager C, Christiansen C.

Bone. 1997 Jan;20(1):63-7.PMID: 8988349 [PubMed - indexed for MEDLINE]Related articles

Acute effects of calcitonin nasal spray on serum C-telopeptide of type 1 collagen (CTx) levels in elderly osteopenic women with increased bone turnover.

Srivastava AK, Libanati C, Hohmann O, Kriegman A, Baylink DJ.

Calcif Tissue Int. 2004 Dec;75(6):477-81. Epub 2004 Sep 16.PMID: 15365658 [PubMed - indexed for MEDLINE]Related articles

Bioavailability and biological efficacy of a new oral formulation of salmon calcitonin in healthy volunteers.

Buclin T, Cosma Rochat M, Burckhardt P, Azria M, Attinger M.

J Bone Miner Res. 2002 Aug;17(8):1478-85.PMID: 12162502 [PubMed - indexed for MEDLINE]Related articles

Effect of the cathepsin K inhibitor odanacatib on bone resorption biomarkers in healthy postmenopausal women: two double-blind, randomized, placebo-controlled phase I studies.

Stoch SA, Zajic S, Stone J, Miller DL, Van Dyck K, Gutierrez MJ, De Decker M, Liu L, Liu Q, Scott BB, Panebianco D, Jin B, Duong LT, Gottesdiener K, Wagner JA.

Clin Pharmacol Ther. 2009 Aug;86(2):175-82. Epub 2009 May 6.PMID: 19421185 [PubMed - indexed for MEDLINE]Related articles

Effect of nasal salmon calcitonin on calcium and bone metabolism.

Thamsborg G.

Dan Med Bull. 1999 Apr;46(2):118-26. Review.PMID: 10327295 [PubMed - indexed for MEDLINE]Related articles

Early effect of nasal salmon calcitonin on the bone marker Crosslaps.

Ofluoglu D, Karadag-Saygi E, Canbulat C, Gunduz OH, Kul-Panza E, Akyuz G.

Rheumatol Int. 2006 Feb;26(4):288-91. Epub 2005 May 5.PMID: 15875189 [PubMed - indexed for MEDLINE]Related articles

Nocturnal rise in markers of bone resorption is not abolished by bedtime calcium or calcitonin.

Sairanen S, Tähtelä R, Laitinen K, Karonen SL, Välimäki MJ.

Calcif Tissue Int. 1994 Nov;55(5):349-52.PMID: 7866915 [PubMed - indexed for MEDLINE]Related articles

The effect of intranasal salmon calcitonin on postmenopausal bone turnover as assessed by biochemical markers: evidence of maximal effect after 8 weeks of continuous treatment.

Kraenzlin ME, Seibel MJ, Trechsel U, Boerlin V, Azria M, Kraenzlin CA, Haas HG.

Calcif Tissue Int. 1996 Apr;58(4):216-20.PMID: 8661950 [PubMed - indexed for MEDLINE]Related articles