PubMed

Mutations on the Switch III region and the alpha3 helix of Galpha16 differentially affect receptor coupling and regulation of downstream effectors.

Yu MY, Ho MK, Liu AM, Wong YH.

J Mol Signal. 2008 Nov 22;3:17.PMID: 19025606 [PubMed - in process]Free PMC ArticleFree textRelated citations

Galpha16 activates Ras by forming a complex with tetratricopeptide repeat 1 (TPR1) and Son of Sevenless (SOS).

Liu AM, Lo RK, Lee MM, Wang Y, Yeung WW, Ho MK, Su Y, Ye RD, Wong YH.

Cell Signal. 2010 Oct;22(10):1448-58.PMID: 20639119 [PubMed - in process]Related citations

Identification of a stretch of six divergent amino acids on the alpha5 helix of Galpha16 as a major determinant of the promiscuity and efficiency of receptor coupling.

Ho MK, Chan JH, Wong CS, Wong YH.

Biochem J. 2004 Jun 1;380(Pt 2):361-9.PMID: 15005654 [PubMed - indexed for MEDLINE]Free PMC ArticleFree textRelated citations

Two basic amino acids in the second inner loop of the interleukin-8 receptor are essential for Galpha16 coupling.

Xie W, Jiang H, Wu Y, Wu D.

J Biol Chem. 1997 Oct 3;272(40):24948-51.PMID: 9312098 [PubMed - indexed for MEDLINE]Free ArticleRelated citations

Gbeta3 forms distinct dimers with specific Ggamma subunits and preferentially activates the beta3 isoform of phospholipase C.

Poon LS, Chan AS, Wong YH.

Cell Signal. 2009 May;21(5):737-44. Epub 2009 Jan 9.PMID: 19168127 [PubMed - indexed for MEDLINE]Related citations

The RhoA-specific guanine nucleotide exchange factor p63RhoGEF binds to activated Galpha(16) and inhibits the canonical phospholipase Cbeta pathway.

Yeung WW, Wong YH.

Cell Signal. 2009 Aug;21(8):1317-25. Epub 2009 Apr 5.PMID: 19332116 [PubMed - indexed for MEDLINE]Related citations

Sprouty4 negatively regulates protein kinase C activation by inhibiting phosphatidylinositol 4,5-biphosphate hydrolysis.

Ayada T, Taniguchi K, Okamoto F, Kato R, Komune S, Takaesu G, Yoshimura A.

Oncogene. 2009 Feb 26;28(8):1076-88. Epub 2009 Jan 12.PMID: 19137008 [PubMed - indexed for MEDLINE]Related citations

Engineered socket study of signaling through a four-helix bundle: evidence for a yin-yang mechanism in the kinase control module of the aspartate receptor.

Swain KE, Gonzalez MA, Falke JJ.

Biochemistry. 2009 Oct 6;48(39):9266-77.PMID: 19705835 [PubMed - indexed for MEDLINE]Related citations

Phosphatidic acid regulates signal output by G protein coupled receptors through direct interaction with phospholipase C-beta(1).

Litosch I, Pujari R, Lee SJ.

Cell Signal. 2009 Sep;21(9):1379-84. Epub 2009 May 3.PMID: 19414067 [PubMed - indexed for MEDLINE]Related citations

CCR1-mediated activation of Nuclear Factor-kappaB in THP-1 monocytic cells involves Pertussis Toxin-insensitive Galpha(14) and Galpha(16) signaling cascades.

Lee MM, Wong YH.

J Leukoc Biol. 2009 Dec;86(6):1319-29. Epub 2009 Aug 17.PMID: 19687291 [PubMed - indexed for MEDLINE]Related citations

Molecular dissection of human oncostatin M-mediated signal transductions through site-directed mutagenesis.

Liu H, Fenollar-Ferrer C, Cao A, Anselmi C, Carloni P, Liu J.

Int J Mol Med. 2009 Feb;23(2):161-72.PMID: 19148539 [PubMed - indexed for MEDLINE]Related citations

Inhibition of extracellular signal-regulated kinase (ERK) signaling participates in repression of nuclear factor (NF)-kappaB activity by glucocorticoids.

Bladh LG, Johansson-Haque K, Rafter I, Nilsson S, Okret S.

Biochim Biophys Acta. 2009 Mar;1793(3):439-46. Epub 2008 Dec 9.PMID: 19110010 [PubMed - indexed for MEDLINE]Related citations

c-Jun N-terminal kinase binding domain-dependent phosphorylation of mitogen-activated protein kinase kinase 4 and mitogen-activated protein kinase kinase 7 and balancing cross-talk between c-Jun N-terminal kinase and extracellular signal-regulated kinase pathways in cortical neurons.

Repici M, Mare L, Colombo A, Ploia C, Sclip A, Bonny C, Nicod P, Salmona M, Borsello T.

Neuroscience. 2009 Mar 3;159(1):94-103. Epub 2008 Dec 14.PMID: 19135136 [PubMed - indexed for MEDLINE]Related citations

Supraspinal Gbetagamma-dependent stimulation of PLCbeta originating from G inhibitory protein-mu opioid receptor-coupling is necessary for morphine induced acute hyperalgesia.

Bianchi E, Norcini M, Smrcka A, Ghelardini C.

J Neurochem. 2009 Oct;111(1):171-80. Epub 2009 Jul 27.PMID: 19656263 [PubMed - indexed for MEDLINE]Related citations

GCK is essential to systemic inflammation and pattern recognition receptor signaling to JNK and p38.

Zhong J, Gavrilescu LC, Molnár A, Murray L, Garafalo S, Kehrl JH, Simon AR, Van Etten RA, Kyriakis JM.

Proc Natl Acad Sci U S A. 2009 Mar 17;106(11):4372-7. Epub 2009 Feb 25.PMID: 19246396 [PubMed - indexed for MEDLINE]Free PMC ArticleFree textRelated citations

Poxvirus host range protein CP77 contains an F-box-like domain that is necessary to suppress NF-kappaB activation by tumor necrosis factor alpha but is independent of its host range function.

Chang SJ, Hsiao JC, Sonnberg S, Chiang CT, Yang MH, Tzou DL, Mercer AA, Chang W.

J Virol. 2009 May;83(9):4140-52. Epub 2009 Feb 11.PMID: 19211746 [PubMed - indexed for MEDLINE]Free PMC ArticleFree textRelated citations

Epidermal growth factor receptor phosphorylation sites Ser991 and Tyr998 are implicated in the regulation of receptor endocytosis and phosphorylations at Ser1039 and Thr1041.

Tong J, Taylor P, Peterman SM, Prakash A, Moran MF.

Mol Cell Proteomics. 2009 Sep;8(9):2131-44. Epub 2009 Jun 15.PMID: 19531499 [PubMed - indexed for MEDLINE]Free PMC ArticleFree textRelated citations

Alternate pathways preserve tumor necrosis factor-alpha production after nuclear factor-kappaB inhibition in neonatal cerebral hypoxia-ischemia.

Nijboer CH, Heijnen CJ, Groenendaal F, van Bel F, Kavelaars A.

Stroke. 2009 Oct;40(10):3362-8. Epub 2009 Jul 23.PMID: 19628795 [PubMed - indexed for MEDLINE]Related citations

X-linked inhibitor of apoptosis protein and its E3 ligase activity promote transforming growth factor-{beta}-mediated nuclear factor-{kappa}B activation during breast cancer progression.

Neil JR, Tian M, Schiemann WP.

J Biol Chem. 2009 Aug 7;284(32):21209-17. Epub 2009 Jun 15.PMID: 19531477 [PubMed - indexed for MEDLINE]Related citations

Cysteinyl leukotrienes induce monocyte chemoattractant protein-1 in human monocyte/macrophages via mitogen-activated protein kinase and nuclear factor-kappaB pathways.

Hashimoto K, Ichiyama T, Hasegawa M, Hasegawa S, Matsubara T, Furukawa S.

Int Arch Allergy Immunol. 2009;149(3):275-82. Epub 2009 Feb 12.PMID: 19218821 [PubMed - indexed for MEDLINE]Related citations