PubMed

PTTG: an important target gene for ovarian cancer therapy.

Panguluri SK, Yeakel C, Kakar SS.

J Ovarian Res. 2008 Oct 20;1(1):6.PMID: 19014669 [PubMed]Free PMC ArticleFree textRelated citations

Pituitary tumor transforming gene: an important gene in normal cellular functions and tumorigenesis.

Bradshaw C, Kakar SS.

Histol Histopathol. 2007 Feb;22(2):219-26. Review.PMID: 17149695 [PubMed - indexed for MEDLINE]Related citations

Development of cystic glandular hyperplasia of the endometrium in Mullerian inhibitory substance type II receptor-pituitary tumor transforming gene transgenic mice.

El-Naggar SM, Malik MT, Martin A, Moore JP, Proctor M, Hamid T, Kakar SS.

J Endocrinol. 2007 Jul;194(1):179-91.PMID: 17592032 [PubMed - indexed for MEDLINE]Free ArticleRelated citations

Regulation of angiogenesis and invasion by human Pituitary tumor transforming gene (PTTG) through increased expression and secretion of matrix metalloproteinase-2 (MMP-2).

Malik MT, Kakar SS.

Mol Cancer. 2006 Nov 10;5:61.PMID: 17096843 [PubMed - indexed for MEDLINE]Free PMC ArticleFree textRelated citations

Effect of PTTG on endogenous gene expression in HEK 293 cells.

Panguluri SK, Kakar SS.

BMC Genomics. 2009 Dec 3;10:577.PMID: 19958546 [PubMed - indexed for MEDLINE]Free PMC ArticleFree textRelated citations

Pituitary tumor-transforming gene in endocrine and other neoplasms: a review and update.

Salehi F, Kovacs K, Scheithauer BW, Lloyd RV, Cusimano M.

Endocr Relat Cancer. 2008 Sep;15(3):721-43. Review.PMID: 18753362 [PubMed - indexed for MEDLINE]Free ArticleRelated citations

Small interfering RNA against PTTG: a novel therapy for ovarian cancer.

El-Naggar SM, Malik MT, Kakar SS.

Int J Oncol. 2007 Jul;31(1):137-43.PMID: 17549414 [PubMed - indexed for MEDLINE]Related citations

The emerging role of pituitary tumor transforming gene in tumorigenesis.

Tfelt-Hansen J, Kanuparthi D, Chattopadhyay N.

Clin Med Res. 2006 Jun;4(2):130-7. Review.PMID: 16809406 [PubMed - indexed for MEDLINE]Free PMC ArticleFree textRelated citations

PTTG/securin activates expression of p53 and modulates its function.

Hamid T, Kakar SS.

Mol Cancer. 2004 Jul 8;3:18.PMID: 15242522 [PubMed - indexed for MEDLINE]Free PMC ArticleFree textRelated citations

Early involvement of estrogen-induced pituitary tumor transforming gene and fibroblast growth factor expression in prolactinoma pathogenesis.

Heaney AP, Horwitz GA, Wang Z, Singson R, Melmed S.

Nat Med. 1999 Nov;5(11):1317-21.PMID: 10546001 [PubMed - indexed for MEDLINE]Related citations

Discordant proliferation and differentiation in pituitary tumor-transforming gene-null bone marrow stem cells.

Rubinek T, Chesnokova V, Wolf I, Wawrowsky K, Vlotides G, Melmed S.

Am J Physiol Cell Physiol. 2007 Sep;293(3):C1082-92. Epub 2007 Jul 11.PMID: 17626243 [PubMed - indexed for MEDLINE]Free ArticleRelated citations

Pituitary tumor-transforming gene regulates multiple downstream angiogenic genes in thyroid cancer.

Kim DS, Franklyn JA, Stratford AL, Boelaert K, Watkinson JC, Eggo MC, McCabe CJ.

J Clin Endocrinol Metab. 2006 Mar;91(3):1119-28. Epub 2006 Jan 4.PMID: 16394085 [PubMed - indexed for MEDLINE]Free ArticleRelated citations

Suppression of lung cancer with siRNA targeting PTTG.

Kakar SS, Malik MT.

Int J Oncol. 2006 Aug;29(2):387-95.PMID: 16820881 [PubMed - indexed for MEDLINE]Related citations

Expression of pituitary tumour transforming gene (PTTG) and fibroblast growth factor-2 (FGF-2) in human pituitary adenomas: relationships to clinical tumour behaviour.

McCabe CJ, Khaira JS, Boelaert K, Heaney AP, Tannahill LA, Hussain S, Mitchell R, Olliff J, Sheppard MC, Franklyn JA, Gittoes NJ.

Clin Endocrinol (Oxf). 2003 Feb;58(2):141-50.PMID: 12580928 [PubMed - indexed for MEDLINE]Related citations

Structure, expression, and function of human pituitary tumor-transforming gene (PTTG).

Zhang X, Horwitz GA, Prezant TR, Valentini A, Nakashima M, Bronstein MD, Melmed S.

Mol Endocrinol. 1999 Jan;13(1):156-66.PMID: 9892021 [PubMed - indexed for MEDLINE]Free ArticleRelated citations

The pituitary tumor-transforming gene promotes angiogenesis in a mouse model of follicular thyroid cancer.

Kim CS, Ying H, Willingham MC, Cheng SY.

Carcinogenesis. 2007 May;28(5):932-9. Epub 2006 Nov 24.PMID: 17127711 [PubMed - indexed for MEDLINE]Free ArticleRelated citations

PTTG is a secretory protein in human pituitary adenomas and in mouse pituitary tumor cell lines.

Minematsu T, Egashira N, Kajiya H, Takei M, Takekoshi S, Itoh Y, Tsukamoto H, Itoh J, Sanno N, Teramoto A, Osamura RY.

Endocr Pathol. 2007 Spring;18(1):8-15.PMID: 17652795 [PubMed - indexed for MEDLINE]Related citations

Pituitary tumour transforming gene (PTTG) induces genetic instability in thyroid cells.

Kim D, Pemberton H, Stratford AL, Buelaert K, Watkinson JC, Lopes V, Franklyn JA, McCabe CJ.

Oncogene. 2005 Jul 14;24(30):4861-6.PMID: 15897900 [PubMed - indexed for MEDLINE]Related citations

Vascular endothelial growth factor, its receptor KDR/Flk-1, and pituitary tumor transforming gene in pituitary tumors.

McCabe CJ, Boelaert K, Tannahill LA, Heaney AP, Stratford AL, Khaira JS, Hussain S, Sheppard MC, Franklyn JA, Gittoes NJ.

J Clin Endocrinol Metab. 2002 Sep;87(9):4238-44.PMID: 12213878 [PubMed - indexed for MEDLINE]Free ArticleRelated citations

Characterization of the role of Sp1 and NF-Y in differential regulation of PTTG/securin expression in tumor cells.

Clem AL, Hamid T, Kakar SS.

Gene. 2003 Dec 11;322:113-21.PMID: 14644503 [PubMed - indexed for MEDLINE]Related citations