PubMed

Overexpression of SIRT1 protects pancreatic beta-cells against cytokine toxicity by suppressing the nuclear factor-kappaB signaling pathway.

Lee JH, Song MY, Song EK, Kim EK, Moon WS, Han MK, Park JW, Kwon KB, Park BH.

Diabetes. 2009 Feb;58(2):344-51. Epub 2008 Nov 13.PMID: 19008341 [PubMed - indexed for MEDLINE]Related articlesFree article

Activation of peroxisome proliferator-activated receptor-gamma protects pancreatic beta-cells from cytokine-induced cytotoxicity via NF kappaB pathway.

Kim EK, Kwon KB, Koo BS, Han MJ, Song MY, Song EK, Han MK, Park JW, Ryu DG, Park BH.

Int J Biochem Cell Biol. 2007;39(6):1260-75. Epub 2007 Apr 19.PMID: 17521952 [PubMed - indexed for MEDLINE]Related articles

Fructus Xanthii extract protects against cytokine-induced damage in pancreatic beta-cells through suppression of NF-kappaB activation.

Song MY, Kim EK, Lee HJ, Park JW, Ryu DG, Kwon KB, Park BH.

Int J Mol Med. 2009 Apr;23(4):547-53.PMID: 19288032 [PubMed - indexed for MEDLINE]Related articles

Radix asari extract protects pancreatic beta cells against cytokine-induced toxicity: implication of the NF-kappaB-iNOS signaling cascade.

Song MY, Kim KA, Lee SY, Kim EK, Lv N, Lee JH, Park JW, Ryu DG, Kwon KB, Park BH.

Int J Mol Med. 2007 Nov;20(5):769-75.PMID: 17912472 [PubMed - indexed for MEDLINE]Related articles

Flavonoids protect against cytokine-induced pancreatic beta-cell damage through suppression of nuclear factor kappaB activation.

Kim EK, Kwon KB, Song MY, Han MJ, Lee JH, Lee YR, Lee JH, Ryu DG, Park BH, Park JW.

Pancreas. 2007 Nov;35(4):e1-9.PMID: 18090225 [PubMed - indexed for MEDLINE]Related articles

Radix clematidis extract protects against cytokine- and streptozotocin-induced beta-cell damage by suppressing the NF-kappaB pathway.

Kim EK, Song MY, Hwang TO, Kim HJ, Moon WS, Ryu DG, So HS, Park R, Park JW, Kwon KB, Park BH.

Int J Mol Med. 2008 Sep;22(3):349-56.PMID: 18698494 [PubMed - indexed for MEDLINE]Related articles

Coptidis rhizoma extract protects against cytokine-induced death of pancreatic beta-cells through suppression of NF-kappaB activation.

Kim EK, Kwon KB, Han MJ, Song MY, Lee JH, Lv N, Ka SO, Yeom SR, Kwon YD, Ryu DG, Kim KS, Park JW, Park R, Park BH.

Exp Mol Med. 2007 Apr 30;39(2):149-59.PMID: 17464176 [PubMed - indexed for MEDLINE]Related articlesFree article

JANEX-1, a JAK3 inhibitor, protects pancreatic islets from cytokine toxicity through downregulation of NF-kappaB activation and the JAK/STAT pathway.

Lv N, Kim EK, Song MY, Choi HN, Moon WS, Park SJ, Park JW, Kwon KB, Park BH.

Exp Cell Res. 2009 Jul 15;315(12):2064-71. Epub 2009 May 3.PMID: 19414010 [PubMed - indexed for MEDLINE]Related articles

Guggulsterone, a plant sterol, inhibits NF-kappaB activation and protects pancreatic beta cells from cytokine toxicity.

Lv N, Song MY, Kim EK, Park JW, Kwon KB, Park BH.

Mol Cell Endocrinol. 2008 Jul 16;289(1-2):49-59. Epub 2008 Feb 9.PMID: 18343024 [PubMed - indexed for MEDLINE]Related articles

Inhibitory effect of Artemisia capillaris extract on cytokine-induced nitric oxide formation and cytotoxicity of RINm5F cells.

Kim EK, Kwon KB, Han MJ, Song MY, Lee JH, Lv N, Choi KB, Ryu DG, Kim KS, Park JW, Park BH.

Int J Mol Med. 2007 Mar;19(3):535-40.PMID: 17273805 [PubMed - indexed for MEDLINE]Related articles

Cortex cinnamomi extract prevents streptozotocin- and cytokine-induced beta-cell damage by inhibiting NF-kappaB.

Kwon KB, Kim EK, Jeong ES, Lee YH, Lee YR, Park JW, Ryu DG, Park BH.

World J Gastroenterol. 2006 Jul 21;12(27):4331-7.PMID: 16865774 [PubMed - indexed for MEDLINE]Related articlesFree article

Genistein protects pancreatic beta cells against cytokine-mediated toxicity.

Kim EK, Kwon KB, Song MY, Seo SW, Park SJ, Ka SO, Na L, Kim KA, Ryu DG, So HS, Park R, Park JW, Park BH.

Mol Cell Endocrinol. 2007 Nov 15;278(1-2):18-28. Epub 2007 Aug 15.PMID: 17881116 [PubMed - indexed for MEDLINE]Related articles

Cytokine-mediated induction of anti-apoptotic genes that are linked to nuclear factor kappa-B (NF-kappaB) signalling in human islets and in a mouse beta cell line.

Sarkar SA, Kutlu B, Velmurugan K, Kizaka-Kondoh S, Lee CE, Wong R, Valentine A, Davidson HW, Hutton JC, Pugazhenthi S.

Diabetologia. 2009 Jun;52(6):1092-101. Epub 2009 Apr 3.PMID: 19343319 [PubMed - indexed for MEDLINE]Related articles

Protective effects of St. John's wort extract and its component hyperforin against cytokine-induced cytotoxicity in a pancreatic beta-cell line.

Menegazzi M, Novelli M, Beffy P, D'Aleo V, Tedeschi E, Lupi R, Zoratti E, Marchetti P, Suzuki H, Masiello P.

Int J Biochem Cell Biol. 2008;40(8):1509-21. Epub 2007 Dec 8.PMID: 18226577 [PubMed - indexed for MEDLINE]Related articles

Osteopontin protects the islets and beta-cells from interleukin-1 beta-mediated cytotoxicity through negative feedback regulation of nitric oxide.

Arafat HA, Katakam AK, Chipitsyna G, Gong Q, Vancha AR, Gabbeta J, Dafoe DC.

Endocrinology. 2007 Feb;148(2):575-84. Epub 2006 Nov 16.PMID: 17110428 [PubMed - indexed for MEDLINE]Related articlesFree article

Improvement of the mitochondrial antioxidant defense status prevents cytokine-induced nuclear factor-kappaB activation in insulin-producing cells.

Azevedo-Martins AK, Lortz S, Lenzen S, Curi R, Eizirik DL, Tiedge M.

Diabetes. 2003 Jan;52(1):93-101.PMID: 12502498 [PubMed - indexed for MEDLINE]Related articlesFree article

Regulation by cytokines of the inducible nitric oxide synthase promoter in insulin-producing cells.

Darville MI, Eizirik DL.

Diabetologia. 1998 Sep;41(9):1101-8.PMID: 9754830 [PubMed - indexed for MEDLINE]Related articles

Effect of iNOS and NF-kappaB gene silencing on beta-cell survival and function.

De Paula D, Bentley MV, Mahato RI.

J Drug Target. 2007 Jun;15(5):358-69.PMID: 17541845 [PubMed - indexed for MEDLINE]Related articles

Inhibitory effects of epicatechin on interleukin-1beta-induced inducible nitric oxide synthase expression in RINm5F cells and rat pancreatic islets by down-regulation of NF-kappaB activation.

Kim MJ, Ryu GR, Kang JH, Sim SS, Min DS, Rhie DJ, Yoon SH, Hahn SJ, Jeong IK, Hong KJ, Kim MS, Jo YH.

Biochem Pharmacol. 2004 Nov 1;68(9):1775-85.PMID: 15450943 [PubMed - indexed for MEDLINE]Related articles

Sulforaphane protects against cytokine- and streptozotocin-induced beta-cell damage by suppressing the NF-kappaB pathway.

Song MY, Kim EK, Moon WS, Park JW, Kim HJ, So HS, Park R, Kwon KB, Park BH.

Toxicol Appl Pharmacol. 2009 Feb 15;235(1):57-67. Epub 2008 Nov 21.PMID: 19071154 [PubMed - indexed for MEDLINE]Related articles