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    Results: 1 to 20 of 103

    1.

    Ras signaling influences permissiveness of malignant peripheral nerve sheath tumor cells to oncolytic herpes.

    Farassati F, Pan W, Yamoutpour F, Henke S, Piedra M, Frahm S, Al-Tawil S, Mangrum WI, Parada LF, Rabkin SD, Martuza RL, Kurtz A.

    Am J Pathol. 2008 Dec;173(6):1861-72. Epub 2008 Nov 6.PMID: 18988803 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    Malignant peripheral nerve sheath tumors with high and low Ras-GTP are permissive for oncolytic herpes simplex virus mutants.

    Mahller YY, Rangwala F, Ratner N, Cripe TP.

    Pediatr Blood Cancer. 2006 Jun;46(7):745-54.PMID: 16124003 [PubMed - indexed for MEDLINE]Related articles

    3.

    Sorafenib inhibits growth and mitogen-activated protein kinase signaling in malignant peripheral nerve sheath cells.

    Ambrosini G, Cheema HS, Seelman S, Teed A, Sambol EB, Singer S, Schwartz GK.

    Mol Cancer Ther. 2008 Apr;7(4):890-6.PMID: 18413802 [PubMed - indexed for MEDLINE]Related articlesFree article

    4.

    Ral overactivation in malignant peripheral nerve sheath tumors.

    Bodempudi V, Yamoutpoor F, Pan W, Dudek AZ, Esfandyari T, Piedra M, Babovick-Vuksanovic D, Woo RA, Mautner VF, Kluwe L, Clapp DW, De Vries GH, Thomas SL, Kurtz A, Parada LF, Farassati F.

    Mol Cell Biol. 2009 Jul;29(14):3964-74. Epub 2009 May 4.PMID: 19414599 [PubMed - indexed for MEDLINE]Related articles

    5.

    Oncolytic HSV and erlotinib inhibit tumor growth and angiogenesis in a novel malignant peripheral nerve sheath tumor xenograft model.

    Mahller YY, Vaikunth SS, Currier MA, Miller SJ, Ripberger MC, Hsu YH, Mehrian-Shai R, Collins MH, Crombleholme TM, Ratner N, Cripe TP.

    Mol Ther. 2007 Feb;15(2):279-86.PMID: 17235305 [PubMed - indexed for MEDLINE]Related articles

    6.

    Oncogenes in Ras signalling pathway dictate host-cell permissiveness to herpes simplex virus 1.

    Farassati F, Yang AD, Lee PW.

    Nat Cell Biol. 2001 Aug;3(8):745-50.PMID: 11483960 [PubMed - indexed for MEDLINE]Related articles

    7.

    Brain lipid binding protein in axon-Schwann cell interactions and peripheral nerve tumorigenesis.

    Miller SJ, Li H, Rizvi TA, Huang Y, Johansson G, Bowersock J, Sidani A, Vitullo J, Vogel K, Parysek LM, DeClue JE, Ratner N.

    Mol Cell Biol. 2003 Mar;23(6):2213-24.PMID: 12612091 [PubMed - indexed for MEDLINE]Related articlesFree article

    8.

    Molecular analysis of human cancer cells infected by an oncolytic HSV-1 reveals multiple upregulated cellular genes and a role for SOCS1 in virus replication.

    Mahller YY, Sakthivel B, Baird WH, Aronow BJ, Hsu YH, Cripe TP, Mehrian-Shai R.

    Cancer Gene Ther. 2008 Nov;15(11):733-41. Epub 2008 Jun 13.PMID: 18551144 [PubMed - indexed for MEDLINE]Related articles

    9.

    Transcription factors down-stream of Ras as molecular indicators for targeting malignancies with oncolytic herpes virus.

    Esfandyari T, Tefferi A, Szmidt A, Alain T, Zwolak P, Lasho T, Lee PW, Farassati F.

    Mol Oncol. 2009 Dec;3(5-6):464-8. Epub 2009 Jul 28.PMID: 19766068 [PubMed - in process]Related articles

    10.

    The Ras inhibitor farnesylthiosalicylic acid as a potential therapy for neurofibromatosis type 1.

    Barkan B, Starinsky S, Friedman E, Stein R, Kloog Y.

    Clin Cancer Res. 2006 Sep 15;12(18):5533-42.PMID: 17000690 [PubMed - indexed for MEDLINE]Related articlesFree article

    11.

    H-Ras-specific activation of Rac-MKK3/6-p38 pathway: its critical role in invasion and migration of breast epithelial cells.

    Shin I, Kim S, Song H, Kim HR, Moon A.

    J Biol Chem. 2005 Apr 15;280(15):14675-83. Epub 2005 Jan 27.PMID: 15677464 [PubMed - indexed for MEDLINE]Related articlesFree article

    12.

    Dominant-negative fibroblast growth factor receptor expression enhances antitumoral potency of oncolytic herpes simplex virus in neural tumors.

    Liu TC, Zhang T, Fukuhara H, Kuroda T, Todo T, Canron X, Bikfalvi A, Martuza RL, Kurtz A, Rabkin SD.

    Clin Cancer Res. 2006 Nov 15;12(22):6791-9.PMID: 17121900 [PubMed - indexed for MEDLINE]Related articlesFree article

    13.

    The RAS/Raf1/MEK/ERK signaling pathway facilitates VSV-mediated oncolysis: implication for the defective interferon response in cancer cells.

    Noser JA, Mael AA, Sakuma R, Ohmine S, Marcato P, Lee PW, Ikeda Y.

    Mol Ther. 2007 Aug;15(8):1531-6. Epub 2007 May 15.PMID: 17505473 [PubMed - indexed for MEDLINE]Related articles

    14.

    Reovirus oncolysis: the Ras/RalGEF/p38 pathway dictates host cell permissiveness to reovirus infection.

    Norman KL, Hirasawa K, Yang AD, Shields MA, Lee PW.

    Proc Natl Acad Sci U S A. 2004 Jul 27;101(30):11099-104. Epub 2004 Jul 19.PMID: 15263068 [PubMed - indexed for MEDLINE]Related articlesFree article

    15.

    Schwann cell lines derived from malignant peripheral nerve sheath tumors respond abnormally to platelet-derived growth factor-BB.

    Dang I, DeVries GH.

    J Neurosci Res. 2005 Feb 1;79(3):318-28.PMID: 15602756 [PubMed - indexed for MEDLINE]Related articles

    16.

    Induction of apoptosis in neurofibromatosis type 1 malignant peripheral nerve sheath tumor cell lines by a combination of novel farnesyl transferase inhibitors and lovastatin.

    Wojtkowiak JW, Fouad F, LaLonde DT, Kleinman MD, Gibbs RA, Reiners JJ Jr, Borch RF, Mattingly RR.

    J Pharmacol Exp Ther. 2008 Jul;326(1):1-11. Epub 2008 Mar 26.PMID: 18367665 [PubMed - indexed for MEDLINE]Related articlesFree article

    17.

    Roles of the RAF/MEK/ERK and PI3K/PTEN/AKT pathways in malignant transformation and drug resistance.

    McCubrey JA, Steelman LS, Abrams SL, Lee JT, Chang F, Bertrand FE, Navolanic PM, Terrian DM, Franklin RA, D'Assoro AB, Salisbury JL, Mazzarino MC, Stivala F, Libra M.

    Adv Enzyme Regul. 2006;46:249-79. Epub 2006 Jul 18.PMID: 16854453 [PubMed - indexed for MEDLINE]Related articles

    18.

    Angiogenic response caused by oncolytic herpes simplex virus-induced reduced thrombospondin expression can be prevented by specific viral mutations or by administering a thrombospondin-derived peptide.

    Aghi M, Rabkin SD, Martuza RL.

    Cancer Res. 2007 Jan 15;67(2):440-4.PMID: 17234749 [PubMed - indexed for MEDLINE]Related articlesFree article

    19.

    Activation of the neuregulin-1/ErbB signaling pathway promotes the proliferation of neoplastic Schwann cells in human malignant peripheral nerve sheath tumors.

    Stonecypher MS, Byer SJ, Grizzle WE, Carroll SL.

    Oncogene. 2005 Aug 25;24(36):5589-605.PMID: 15897877 [PubMed - indexed for MEDLINE]Related articles

    20.

    Utilizing ras signaling pathway to direct selective replication of herpes simplex virus-1.

    Pan W, Bodempudi V, Esfandyari T, Farassati F.

    PLoS One. 2009 Aug 4;4(8):e6514.PMID: 19652721 [PubMed - in process]Related articlesFree article

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