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    Results: 1 to 20 of 112

    1.

    Hypoxia decreases insulin signaling pathways in adipocytes.

    Regazzetti C, Peraldi P, Grémeaux T, Najem-Lendom R, Ben-Sahra I, Cormont M, Bost F, Le Marchand-Brustel Y, Tanti JF, Giorgetti-Peraldi S.

    Diabetes. 2009 Jan;58(1):95-103. Epub 2008 Nov 4.PMID: 18984735 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    HIF-1 regulates hypoxia- and insulin-induced expression of apelin in adipocytes.

    Glassford AJ, Yue P, Sheikh AY, Chun HJ, Zarafshar S, Chan DA, Reaven GM, Quertermous T, Tsao PS.

    Am J Physiol Endocrinol Metab. 2007 Dec;293(6):E1590-6. Epub 2007 Sep 18.PMID: 17878221 [PubMed - indexed for MEDLINE]Related articlesFree article

    3.

    Interleukin-1beta-induced insulin resistance in adipocytes through down-regulation of insulin receptor substrate-1 expression.

    Jager J, Grémeaux T, Cormont M, Le Marchand-Brustel Y, Tanti JF.

    Endocrinology. 2007 Jan;148(1):241-51. Epub 2006 Oct 12.PMID: 17038556 [PubMed - indexed for MEDLINE]Related articlesFree article

    4.

    Breathing room: the (un)natural history of adipose microhypoxia and insulin resistance.

    Copps KD, White MF.

    Diabetes. 2009 Jan;58(1):26-7. No abstract available. PMID: 19114728 [PubMed - indexed for MEDLINE]Related articlesFree article

    5.

    Overexpression of protein-tyrosine phosphatase-1B in adipocytes inhibits insulin-stimulated phosphoinositide 3-kinase activity without altering glucose transport or Akt/Protein kinase B activation.

    Venable CL, Frevert EU, Kim YB, Fischer BM, Kamatkar S, Neel BG, Kahn BB.

    J Biol Chem. 2000 Jun 16;275(24):18318-26.PMID: 10751417 [PubMed - indexed for MEDLINE]Related articlesFree article

    6.

    Dexamethasone-induced insulin resistance in 3T3-L1 adipocytes is due to inhibition of glucose transport rather than insulin signal transduction.

    Sakoda H, Ogihara T, Anai M, Funaki M, Inukai K, Katagiri H, Fukushima Y, Onishi Y, Ono H, Fujishiro M, Kikuchi M, Oka Y, Asano T.

    Diabetes. 2000 Oct;49(10):1700-8.PMID: 11016454 [PubMed - indexed for MEDLINE]Related articlesFree article

    7.

    Hypoxia dysregulates the production of adiponectin and plasminogen activator inhibitor-1 independent of reactive oxygen species in adipocytes.

    Chen B, Lam KS, Wang Y, Wu D, Lam MC, Shen J, Wong L, Hoo RL, Zhang J, Xu A.

    Biochem Biophys Res Commun. 2006 Mar 10;341(2):549-56. Epub 2006 Jan 13.PMID: 16427606 [PubMed - indexed for MEDLINE]Related articles

    8.

    Interleukin-6 (IL-6) induces insulin resistance in 3T3-L1 adipocytes and is, like IL-8 and tumor necrosis factor-alpha, overexpressed in human fat cells from insulin-resistant subjects.

    Rotter V, Nagaev I, Smith U.

    J Biol Chem. 2003 Nov 14;278(46):45777-84. Epub 2003 Sep 2.PMID: 12952969 [PubMed - indexed for MEDLINE]Related articlesFree article

    9.

    Chronic endothelin-1 treatment leads to heterologous desensitization of insulin signaling in 3T3-L1 adipocytes.

    Ishibashi KI, Imamura T, Sharma PM, Huang J, Ugi S, Olefsky JM.

    J Clin Invest. 2001 May;107(9):1193-202.PMID: 11342583 [PubMed - indexed for MEDLINE]Related articlesFree article

    10.

    Modulation and lack of cross-talk between signal transducer and activator of transcription 5 and Suppressor of cytokine signaling-3 in insulin and growth hormone signaling in 3T3-L1 adipocytes.

    Story DJ, Stephens JM.

    Obesity (Silver Spring). 2006 Aug;14(8):1303-11.PMID: 16988072 [PubMed - indexed for MEDLINE]Related articles

    11.

    Impact of Src homology 2-containing inositol 5'-phosphatase 2 on the regulation of insulin signaling leading to protein synthesis in 3T3-L1 adipocytes cultured with excess amino acids.

    Murakami S, Sasaoka T, Wada T, Fukui K, Nagira K, Ishihara H, Usui I, Kobayashi M.

    Endocrinology. 2004 Jul;145(7):3215-23. Epub 2004 Mar 24.PMID: 15044364 [PubMed - indexed for MEDLINE]Related articlesFree article

    12.

    Long-term treatment with interleukin-1beta induces insulin resistance in murine and human adipocytes.

    Lagathu C, Yvan-Charvet L, Bastard JP, Maachi M, Quignard-Boulangé A, Capeau J, Caron M.

    Diabetologia. 2006 Sep;49(9):2162-73. Epub 2006 Jul 25.PMID: 16865359 [PubMed - indexed for MEDLINE]Related articles

    13.

    Protein phosphatase-2C alpha as a positive regulator of insulin sensitivity through direct activation of phosphatidylinositol 3-kinase in 3T3-L1 adipocytes.

    Yoshizaki T, Maegawa H, Egawa K, Ugi S, Nishio Y, Imamura T, Kobayashi T, Tamura S, Olefsky JM, Kashiwagi A.

    J Biol Chem. 2004 May 21;279(21):22715-26. Epub 2004 Mar 11.PMID: 15016818 [PubMed - indexed for MEDLINE]Related articlesFree article

    14.

    Aldosterone inhibits insulin-induced glucose uptake by degradation of insulin receptor substrate (IRS) 1 and IRS2 via a reactive oxygen species-mediated pathway in 3T3-L1 adipocytes.

    Wada T, Ohshima S, Fujisawa E, Koya D, Tsuneki H, Sasaoka T.

    Endocrinology. 2009 Apr;150(4):1662-9. Epub 2008 Dec 18.PMID: 19095745 [PubMed - indexed for MEDLINE]Related articles

    15.

    Role of hypoxia-inducible factor (HIF)-1alpha versus HIF-2alpha in the regulation of HIF target genes in response to hypoxia, insulin-like growth factor-I, or loss of von Hippel-Lindau function: implications for targeting the HIF pathway.

    Carroll VA, Ashcroft M.

    Cancer Res. 2006 Jun 15;66(12):6264-70.PMID: 16778202 [PubMed - indexed for MEDLINE]Related articlesFree article

    16.

    Effects of prolyl hydroxylase inhibitors on adipogenesis and hypoxia inducible factor 1 alpha levels under normoxic conditions.

    Floyd ZE, Kilroy G, Wu X, Gimble JM.

    J Cell Biochem. 2007 Aug 15;101(6):1545-57.PMID: 17370314 [PubMed - indexed for MEDLINE]Related articles

    17.

    Inhibition of insulin sensitivity by free fatty acids requires activation of multiple serine kinases in 3T3-L1 adipocytes.

    Gao Z, Zhang X, Zuberi A, Hwang D, Quon MJ, Lefevre M, Ye J.

    Mol Endocrinol. 2004 Aug;18(8):2024-34. Epub 2004 May 13.PMID: 15143153 [PubMed - indexed for MEDLINE]Related articlesFree article

    18.

    Transcriptional regulation of the hypoxia inducible factor-2alpha (HIF-2alpha) gene during adipose differentiation in 3T3-L1 cells.

    Wada T, Shimba S, Tezuka M.

    Biol Pharm Bull. 2006 Jan;29(1):49-54.PMID: 16394508 [PubMed - indexed for MEDLINE]Related articlesFree article

    19.

    Hypoxia-inducible factor-1alpha and hypoxia-inducible factor-2alpha are expressed in kaposi sarcoma and modulated by insulin-like growth factor-I.

    Catrina SB, Botusan IR, Rantanen A, Catrina AI, Pyakurel P, Savu O, Axelson M, Biberfeld P, Poellinger L, Brismar K.

    Clin Cancer Res. 2006 Aug 1;12(15):4506-14.PMID: 16899596 [PubMed - indexed for MEDLINE]Related articlesFree article

    20.

    Platelet-derived growth factor (PDGF) stimulates glucose transport in 3T3-L1 adipocytes overexpressing PDGF receptor by a pathway independent of insulin receptor substrates.

    Whiteman EL, Chen JJ, Birnbaum MJ.

    Endocrinology. 2003 Sep;144(9):3811-20.PMID: 12933652 [PubMed - indexed for MEDLINE]Related articlesFree article

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