PubMed

Site-specific GlcNAcylation of human erythrocyte proteins: potential biomarker(s) for diabetes.

Wang Z, Park K, Comer F, Hsieh-Wilson LC, Saudek CD, Hart GW.

Diabetes. 2009 Feb;58(2):309-17. Epub 2008 Nov 4.PMID: 18984734 [PubMed - indexed for MEDLINE]Related articlesFree article

Cross-talk between GlcNAcylation and phosphorylation: roles in insulin resistance and glucose toxicity.

Copeland RJ, Bullen JW, Hart GW.

Am J Physiol Endocrinol Metab. 2008 Jul;295(1):E17-28. Epub 2008 Apr 29. Review.PMID: 18445751 [PubMed - indexed for MEDLINE]Related articlesFree article

Elevation of the post-translational modification of proteins by O-linked N-acetylglucosamine leads to deterioration of the glucose-stimulated insulin secretion in the pancreas of diabetic Goto-Kakizaki rats.

Akimoto Y, Hart GW, Wells L, Vosseller K, Yamamoto K, Munetomo E, Ohara-Imaizumi M, Nishiwaki C, Nagamatsu S, Hirano H, Kawakami H.

Glycobiology. 2007 Feb;17(2):127-40. Epub 2006 Nov 9.PMID: 17095531 [PubMed - indexed for MEDLINE]Related articlesFree article

Identification of structural and functional O-linked N-acetylglucosamine-bearing proteins in Xenopus laevis oocyte.

Dehennaut V, Slomianny MC, Page A, Vercoutter-Edouart AS, Jessus C, Michalski JC, Vilain JP, Bodart JF, Lefebvre T.

Mol Cell Proteomics. 2008 Nov;7(11):2229-45. Epub 2008 Jul 9.PMID: 18617508 [PubMed - indexed for MEDLINE]Related articlesFree article

Increased enzymatic O-GlcNAcylation of mitochondrial proteins impairs mitochondrial function in cardiac myocytes exposed to high glucose.

Hu Y, Suarez J, Fricovsky E, Wang H, Scott BT, Trauger SA, Han W, Hu Y, Oyeleye MO, Dillmann WH.

J Biol Chem. 2009 Jan 2;284(1):547-55. Epub 2008 Nov 12.PMID: 19004814 [PubMed - indexed for MEDLINE]Related articles

O-GlcNAc modification in diabetes and Alzheimer's disease.

Dias WB, Hart GW.

Mol Biosyst. 2007 Nov;3(11):766-72. Epub 2007 Aug 29. Review.PMID: 17940659 [PubMed - indexed for MEDLINE]Related articles

High glucose and insulin promote O-GlcNAc modification of proteins, including alpha-tubulin.

Walgren JL, Vincent TS, Schey KL, Buse MG.

Am J Physiol Endocrinol Metab. 2003 Feb;284(2):E424-34. Epub 2002 Oct 22.PMID: 12397027 [PubMed - indexed for MEDLINE]Related articlesFree article

Dynamic interplay between O-linked N-acetylglucosaminylation and glycogen synthase kinase-3-dependent phosphorylation.

Wang Z, Pandey A, Hart GW.

Mol Cell Proteomics. 2007 Aug;6(8):1365-79. Epub 2007 May 16.PMID: 17507370 [PubMed - indexed for MEDLINE]Related articlesFree article

Identification of the major site of O-linked beta-N-acetylglucosamine modification in the C terminus of insulin receptor substrate-1.

Ball LE, Berkaw MN, Buse MG.

Mol Cell Proteomics. 2006 Feb;5(2):313-23. Epub 2005 Oct 22.PMID: 16244361 [PubMed - indexed for MEDLINE]Related articlesFree article

O-linked beta-N-acetylglucosamine (O-GlcNAc): Extensive crosstalk with phosphorylation to regulate signaling and transcription in response to nutrients and stress.

Butkinaree C, Park K, Hart GW.

Biochim Biophys Acta. 2009 Aug 6. [Epub ahead of print]PMID: 19647786 [PubMed - as supplied by publisher]Related articles

The hexosamine signaling pathway: deciphering the "O-GlcNAc code".

Love DC, Hanover JA.

Sci STKE. 2005 Nov 29;2005(312):re13. Review.PMID: 16317114 [PubMed - indexed for MEDLINE]Related articles

O-linked GlcNAc modification of cardiac myofilament proteins: a novel regulator of myocardial contractile function.

Ramirez-Correa GA, Jin W, Wang Z, Zhong X, Gao WD, Dias WB, Vecoli C, Hart GW, Murphy AM.

Circ Res. 2008 Dec 5;103(12):1354-8. Epub 2008 Nov 6.PMID: 18988896 [PubMed - indexed for MEDLINE]Related articlesFree article

Cross-talk between GlcNAcylation and phosphorylation: site-specific phosphorylation dynamics in response to globally elevated O-GlcNAc.

Wang Z, Gucek M, Hart GW.

Proc Natl Acad Sci U S A. 2008 Sep 16;105(37):13793-8. Epub 2008 Sep 8.PMID: 18779572 [PubMed - indexed for MEDLINE]Related articlesFree article

Glucose deprivation stimulates O-GlcNAc modification of proteins through up-regulation of O-linked N-acetylglucosaminyltransferase.

Taylor RP, Parker GJ, Hazel MW, Soesanto Y, Fuller W, Yazzie MJ, McClain DA.

J Biol Chem. 2008 Mar 7;283(10):6050-7. Epub 2008 Jan 3.PMID: 18174169 [PubMed - indexed for MEDLINE]Related articlesFree article

Identification of O-GlcNAc sites on proteins.

Whelan SA, Hart GW.

Methods Enzymol. 2006;415:113-33.PMID: 17116471 [PubMed - indexed for MEDLINE]Related articles

Enrichment and site-mapping of O-Linked N-Acetylglucosamine by a combination of chemical/enzymatic tagging, photochemical cleavage, and electron transfer dissociation (ETD) mass spectrometry.

Wang Z, Udeshi ND, O'Malley M, Shabanowitz J, Hunt DF, Hart GW.

Mol Cell Proteomics. 2009 Aug 19. [Epub ahead of print]PMID: 19692427 [PubMed - as supplied by publisher]Related articlesFree article

O-GlcNAc modification of nucleocytoplasmic proteins and diabetes.

Akimoto Y, Hart GW, Hirano H, Kawakami H.

Med Mol Morphol. 2005 Jun;38(2):84-91. Review.PMID: 15944815 [PubMed - indexed for MEDLINE]Related articles

Identification of protein O-GlcNAcylation sites using electron transfer dissociation mass spectrometry on native peptides.

Chalkley RJ, Thalhammer A, Schoepfer R, Burlingame AL.

Proc Natl Acad Sci U S A. 2009 Jun 2;106(22):8894-9. Epub 2009 May 19.PMID: 19458039 [PubMed - indexed for MEDLINE]Related articles

Proteomic analysis of O-GlcNAc modifications derived from streptozotocin and glucosamine induced beta-cell apoptosis.

Park J, Kwon H, Kang Y, Kim Y.

J Biochem Mol Biol. 2007 Nov 30;40(6):1058-68.PMID: 18047804 [PubMed - indexed for MEDLINE]Related articlesFree article

Enhanced O-GlcNAc protein modification is associated with insulin resistance in GLUT1-overexpressing muscles.

Buse MG, Robinson KA, Marshall BA, Hresko RC, Mueckler MM.

Am J Physiol Endocrinol Metab. 2002 Aug;283(2):E241-50.PMID: 12110528 [PubMed - indexed for MEDLINE]Related articlesFree article