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    Results: 1 to 20 of 122

    1.

    Targeting histone deacetylase activity in rheumatoid arthritis and asthma as prototypes of inflammatory disease: should we keep our HATs on?

    Grabiec AM, Tak PP, Reedquist KA.

    Arthritis Res Ther. 2008;10(5):226. Epub 2008 Oct 17. Review.

    PMID:
    18983693
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    2.

    Epigenetic regulation of airway inflammation.

    Adcock IM, Tsaprouni L, Bhavsar P, Ito K.

    Curr Opin Immunol. 2007 Dec;19(6):694-700. Epub 2007 Aug 27. Review.

    PMID:
    17720468
    [PubMed - indexed for MEDLINE]
    3.

    The role of histone deacetylases in asthma and allergic diseases.

    Bhavsar P, Ahmad T, Adcock IM.

    J Allergy Clin Immunol. 2008 Mar;121(3):580-4. Epub 2008 Jan 30. Review.

    PMID:
    18234319
    [PubMed - indexed for MEDLINE]
    4.

    Histone deacetylase inhibitors suppress inflammatory activation of rheumatoid arthritis patient synovial macrophages and tissue.

    Grabiec AM, Krausz S, de Jager W, Burakowski T, Groot D, Sanders ME, Prakken BJ, Maslinski W, Eldering E, Tak PP, Reedquist KA.

    J Immunol. 2010 Mar 1;184(5):2718-28. Epub 2010 Jan 25.

    PMID:
    20100935
    [PubMed - indexed for MEDLINE]
    Free Article
    5.

    Function of histone deacetylase inhibitors in inflammation.

    Grabiec AM, Tak PP, Reedquist KA.

    Crit Rev Immunol. 2011;31(3):233-63. Review.

    PMID:
    21740352
    [PubMed - indexed for MEDLINE]
    6.

    Corticosteroids: the drugs to beat.

    Barnes PJ.

    Eur J Pharmacol. 2006 Mar 8;533(1-3):2-14. Epub 2006 Jan 24. Review.

    PMID:
    16436275
    [PubMed - indexed for MEDLINE]
    7.

    Histone deacetylation: an important mechanism in inflammatory lung diseases.

    Adcock IM, Ito K, Barnes PJ.

    COPD. 2005 Dec;2(4):445-55. Review.

    PMID:
    17147010
    [PubMed - indexed for MEDLINE]
    8.

    Impact of protein acetylation in inflammatory lung diseases.

    Ito K, Charron CE, Adcock IM.

    Pharmacol Ther. 2007 Nov;116(2):249-65. Epub 2007 Jul 24. Review.

    PMID:
    17720252
    [PubMed - indexed for MEDLINE]
    9.

    Histone deacetylase inhibitors in inflammatory disease.

    Halili MA, Andrews MR, Sweet MJ, Fairlie DP.

    Curr Top Med Chem. 2009;9(3):309-19. Review.

    PMID:
    19355993
    [PubMed - indexed for MEDLINE]
    10.

    The role of histone deacetylases (HDACs) in human cancer.

    Ropero S, Esteller M.

    Mol Oncol. 2007 Jun;1(1):19-25. Epub 2007 Mar 7. Review.

    PMID:
    19383284
    [PubMed - indexed for MEDLINE]
    11.

    Histone acetylation and deacetylation: importance in inflammatory lung diseases.

    Barnes PJ, Adcock IM, Ito K.

    Eur Respir J. 2005 Mar;25(3):552-63. Review.

    PMID:
    15738302
    [PubMed - indexed for MEDLINE]
    Free Article
    12.

    Histone deacetylases in RA: epigenetics and epiphenomena.

    Grabiec AM, Reedquist KA.

    Arthritis Res Ther. 2010;12(5):142. Epub 2010 Oct 11.

    PMID:
    20959025
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    13.

    Expression and activity of histone deacetylases in human asthmatic airways.

    Ito K, Caramori G, Lim S, Oates T, Chung KF, Barnes PJ, Adcock IM.

    Am J Respir Crit Care Med. 2002 Aug 1;166(3):392-6.

    PMID:
    12153977
    [PubMed - indexed for MEDLINE]
    Free Article
    14.

    Targeting histone deacetylases for the treatment of cancer and inflammatory diseases.

    Huang L.

    J Cell Physiol. 2006 Dec;209(3):611-6. Review.

    PMID:
    17001696
    [PubMed - indexed for MEDLINE]
    15.

    Regulation of histone deacetylase activities.

    Sengupta N, Seto E.

    J Cell Biochem. 2004 Sep 1;93(1):57-67. Review.

    PMID:
    15352162
    [PubMed - indexed for MEDLINE]
    16.

    A molecular mechanism of action of theophylline: Induction of histone deacetylase activity to decrease inflammatory gene expression.

    Ito K, Lim S, Caramori G, Cosio B, Chung KF, Adcock IM, Barnes PJ.

    Proc Natl Acad Sci U S A. 2002 Jun 25;99(13):8921-6. Epub 2002 Jun 17.

    PMID:
    12070353
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    17.

    Molecular basis of chronic inflammation in lung diseases: new therapeutic approach.

    Mroz RM, Noparlik J, Chyczewska E, Braszko JJ, Holownia A.

    J Physiol Pharmacol. 2007 Nov;58 Suppl 5(Pt 2):453-60. Review.

    PMID:
    18204158
    [PubMed - indexed for MEDLINE]
    Free Article
    18.

    Rationale for the use of histone deacetylase inhibitors as a dual therapeutic modality in multiple sclerosis.

    Gray SG, Dangond F.

    Epigenetics. 2006 Apr-Jun;1(2):67-75. Epub 2006 Mar 5. Review.

    PMID:
    17998807
    [PubMed - indexed for MEDLINE]
    Free Article
    20.

    Depletion of histone deacetylase protein: a common consequence of inflammatory cytokine signaling?

    Gopal YN, Van Dyke MW.

    Cell Cycle. 2006 Dec;5(23):2738-43. Epub 2006 Dec 1.

    PMID:
    17172847
    [PubMed - indexed for MEDLINE]
    Free Article

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