PubMed

Product inhibition of secreted phospholipase A2 may explain lysophosphatidylcholines' unexpected therapeutic properties.

Cunningham TJ, Yao L, Lucena A.

J Inflamm (Lond). 2008 Oct 22;5:17.PMID: 18945345 [PubMed - in process]Related articlesFree article

Inhibition of secreted phospholipase A2 by neuron survival and anti-inflammatory peptide CHEC-9.

Cunningham TJ, Maciejewski J, Yao L.

J Neuroinflammation. 2006 Sep 11;3:25.PMID: 16965626 [PubMed]Related articlesFree article

An essential role for lysophosphatidylcholine in the inhibition of platelet aggregation by secretory phospholipase A2.

Yuan Y, Jackson SP, Newnham HH, Mitchell CA, Salem HH.

Blood. 1995 Dec 1;86(11):4166-74.PMID: 7492774 [PubMed - indexed for MEDLINE]Related articlesFree article

Secreted phospholipase A2 activity in experimental autoimmune encephalomyelitis and multiple sclerosis.

Cunningham TJ, Yao L, Oetinger M, Cort L, Blankenhorn EP, Greenstein JI.

J Neuroinflammation. 2006 Sep 11;3:26.PMID: 16965627 [PubMed]Related articlesFree article

Group IIA secretory PLA2 inhibition by ursolic acid: a potent anti-inflammatory molecule.

Nataraju A, Raghavendra Gowda CD, Rajesh R, Vishwanath BS.

Curr Top Med Chem. 2007;7(8):801-9.PMID: 17456043 [PubMed - indexed for MEDLINE]Related articles

Elevated levels and altered fatty acid composition of plasma lysophosphatidylcholine(lysoPC) in ovarian cancer patients.

Okita M, Gaudette DC, Mills GB, Holub BJ.

Int J Cancer. 1997 Mar 28;71(1):31-4.PMID: 9096662 [PubMed - indexed for MEDLINE]Related articles

Anti-inflammatory action of arachidonoyl lysophosphatidylcholine or 15-hydroperoxy derivative in zymosan A-induced peritonitis.

Hung ND, Kim MR, Sok DE.

Prostaglandins Other Lipid Mediat. 2009 Dec;90(3-4):105-11. Epub 2009 Oct 9.PMID: 19819343 [PubMed - indexed for MEDLINE]Related articles

Analyses of group III secreted phospholipase A2 transgenic mice reveal potential participation of this enzyme in plasma lipoprotein modification, macrophage foam cell formation, and atherosclerosis.

Sato H, Kato R, Isogai Y, Saka G, Ohtsuki M, Taketomi Y, Yamamoto K, Tsutsumi K, Yamada J, Masuda S, Ishikawa Y, Ishii T, Kobayashi T, Ikeda K, Taguchi R, Hatakeyama S, Hara S, Kudo I, Itabe H, Murakami M.

J Biol Chem. 2008 Nov 28;283(48):33483-97. Epub 2008 Sep 18.PMID: 18801741 [PubMed - indexed for MEDLINE]Related articlesFree article

Effect of umbelliferone (7-hydroxycoumarin, 7-HOC) on the enzymatic, edematogenic and necrotic activities of secretory phospholipase A2 (sPLA2) isolated from Crotalus durissus collilineatus venom.

Toyama DO, Marangoni S, Diz-Filho EB, Oliveira SC, Toyama MH.

Toxicon. 2009 Mar 15;53(4):417-26.PMID: 19470355 [PubMed - indexed for MEDLINE]Related articles

Distinguishing phospholipase A2 types in biological samples by employing group-specific assays in the presence of inhibitors.

Lucas KK, Dennis EA.

Prostaglandins Other Lipid Mediat. 2005 Sep;77(1-4):235-48. Review.PMID: 16099408 [PubMed - indexed for MEDLINE]Related articles

Regulation of lipoxygenase activity by polyunsaturated lysophosphatidylcholines or their oxygenation derivatives.

Huang LS, Kim MR, Sok DE.

J Agric Food Chem. 2008 Sep 10;56(17):7808-14. Epub 2008 Aug 5.PMID: 18680379 [PubMed - indexed for MEDLINE]Related articles

Reduction of lipoxidative load by secretory phospholipase A2 inhibition protects against neurovascular injury following experimental stroke in rat.

Hoda MN, Singh I, Singh AK, Khan M.

J Neuroinflammation. 2009 Aug 13;6:21.PMID: 19678934 [PubMed - indexed for MEDLINE]Related articlesFree article

Transgenic expression of group V, but not group X, secreted phospholipase A2 in mice leads to neonatal lethality because of lung dysfunction.

Ohtsuki M, Taketomi Y, Arata S, Masuda S, Ishikawa Y, Ishii T, Takanezawa Y, Aoki J, Arai H, Yamamoto K, Kudo I, Murakami M.

J Biol Chem. 2006 Nov 24;281(47):36420-33. Epub 2006 Sep 28.PMID: 17008322 [PubMed - indexed for MEDLINE]Related articlesFree article

Inhibition of secreted phospholipase A2. 4-glycerol derivatives of 4,5-dihydro-3-(4-tetradecyloxybenzyl)-1,2,4-4H-oxadiazol-5-one with broad activities.

Touaibia M, Djimdé A, Cao F, Boilard E, Bezzine S, Lambeau G, Redeuilh C, Lamouri A, Massicot F, Chau F, Dong CZ, Heymans F.

J Med Chem. 2007 Apr 5;50(7):1618-26. Epub 2007 Mar 3.PMID: 17335183 [PubMed - indexed for MEDLINE]Related articles

Synthesis and evaluation of benzophenone oximes derivatized with sydnone as inhibitors of secretory phospholipase A2 with anti-inflammatory activity.

Kamble RR, Belgur SS, Aladkatti R, Khazi IA.

Chem Pharm Bull (Tokyo). 2009 Jan;57(1):16-21.PMID: 19122311 [PubMed - indexed for MEDLINE]Related articlesFree article

Lysophosphatidylcholine: a chemoattractant to human T lymphocytes.

Ryborg AK, Deleuran B, Thestrup-Pedersen K, Kragballe K.

Arch Dermatol Res. 1994;286(8):462-5.PMID: 7864659 [PubMed - indexed for MEDLINE]Related articles

Structure-activity relationship of 2-oxoamide inhibition of group IVA cytosolic phospholipase A2 and group V secreted phospholipase A2.

Six DA, Barbayianni E, Loukas V, Constantinou-Kokotou V, Hadjipavlou-Litina D, Stephens D, Wong AC, Magrioti V, Moutevelis-Minakakis P, Baker SF, Dennis EA, Kokotos G.

J Med Chem. 2007 Aug 23;50(17):4222-35. Epub 2007 Aug 2.PMID: 17672443 [PubMed - indexed for MEDLINE]Related articles

25-hydroxycholesterol provokes oligodendrocyte cell line apoptosis and stimulates the secreted phospholipase A2 type IIA via LXR beta and PXR.

Trousson A, Bernard S, Petit PX, Liere P, Pianos A, El Hadri K, Lobaccaro JM, Ghandour MS, Raymondjean M, Schumacher M, Massaad C.

J Neurochem. 2009 May;109(4):945-58. Epub 2009 Feb 24.PMID: 19250336 [PubMed - indexed for MEDLINE]Related articles

Inactivation of bee venom phospholipase A2 by a sesquiterpene furanoic acid marine natural product.

Grace KJ, Zavortink D, Jacobs RS.

Biochem Pharmacol. 1994 Apr 20;47(8):1427-34.PMID: 8185650 [PubMed - indexed for MEDLINE]Related articles

Microstructural characterization of lysophosphatidylcholine micellar aggregates: the structural basis for their use as biomembrane mimics.

Vitiello G, Ciccarelli D, Ortona O, D'Errico G.

J Colloid Interface Sci. 2009 Aug 15;336(2):827-33. Epub 2009 Apr 12.PMID: 19414180 [PubMed - indexed for MEDLINE]Related articles