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Essential fatty acids and their metabolites could function as endogenous HMG-CoA reductase and ACE enzyme inhibitors, anti-arrhythmic, anti-hypertensive, anti-atherosclerotic, anti-inflammatory, cytoprotective, and cardioprotective molecules.

Das UN.

Lipids Health Dis. 2008 Oct 15;7:37. Review.PMID: 18922179 [PubMed - indexed for MEDLINE]Related articlesFree article

Do polyunsaturated fatty acids behave like an endogenous "polypill"?

Das UN.

Med Hypotheses. 2008;70(2):430-4. Epub 2007 Jul 10.PMID: 17624683 [PubMed - indexed for MEDLINE]Related articles

Essential Fatty acids - a review.

Das UN.

Curr Pharm Biotechnol. 2006 Dec;7(6):467-82. Review.PMID: 17168664 [PubMed - indexed for MEDLINE]Related articles

Can COX-2 inhibitor-induced increase in cardiovascular disease risk be modified by essential fatty acids?

Das UN.

J Assoc Physicians India. 2005 Jul;53:623-7. Review.PMID: 16190133 [PubMed - indexed for MEDLINE]Related articles

Essential fatty acids: biochemistry, physiology and pathology.

Das UN.

Biotechnol J. 2006 Apr;1(4):420-39. Review.PMID: 16892270 [PubMed - indexed for MEDLINE]Related articles

Biological significance of essential fatty acids.

Das UN.

J Assoc Physicians India. 2006 Apr;54:309-19. Review.PMID: 16944615 [PubMed - indexed for MEDLINE]Related articles

COX-2 inhibitors and metabolism of essential fatty acids.

Das UN.

Med Sci Monit. 2005 Jul;11(7):RA233-7. Epub 2005 Jun 29. Review.PMID: 15990700 [PubMed - indexed for MEDLINE]Related articles

A defect in the activity of Delta6 and Delta5 desaturases may be a factor in the initiation and progression of atherosclerosis.

Das UN.

Prostaglandins Leukot Essent Fatty Acids. 2007 May;76(5):251-68. Epub 2007 Apr 26. Review.PMID: 17466497 [PubMed - indexed for MEDLINE]Related articles

Can essential fatty acids reduce the burden of disease(s)?

Das UN.

Lipids Health Dis. 2008 Mar 18;7:9.PMID: 18348729 [PubMed - indexed for MEDLINE]Related articlesFree article

Folic acid and polyunsaturated fatty acids improve cognitive function and prevent depression, dementia, and Alzheimer's disease--but how and why?

Das UN.

Prostaglandins Leukot Essent Fatty Acids. 2008 Jan;78(1):11-9. Epub 2007 Nov 28. Review.PMID: 18054217 [PubMed - indexed for MEDLINE]Related articles

Essential fatty acids as possible mediators of the actions of statins.

Das UN.

Prostaglandins Leukot Essent Fatty Acids. 2001 Jul;65(1):37-40. Review.PMID: 11487306 [PubMed - indexed for MEDLINE]Related articles

Fatty acid facts, Part III: Cardiovascular disease, or, a fish diet is not fishy.

Pauwels EK, Kostkiewicz M.

Drug News Perspect. 2008 Dec;21(10):552-61. Review.PMID: 19221636 [PubMed - indexed for MEDLINE]Related articles

A strategy to reduce cardiovascular disease by more than 80%.

Wald NJ, Law MR.

BMJ. 2003 Jun 28;326(7404):1419. Erratum in: BMJ. 2006 Sep;60(9):823. BMJ. 2003 Sep 13;327(7415):586. PMID: 12829553 [PubMed - indexed for MEDLINE]Related articlesFree article

Essential fatty acids and acquired immunodeficiency syndrome.

Das UN.

Med Sci Monit. 2005 Jun;11(6):RA206-211. Epub 2005 May 25. Review.PMID: 15917732 [PubMed - indexed for MEDLINE]Related articlesFree article

Essential fatty acid metabolism in patients with essential hypertension, diabetes mellitus and coronary heart disease.

Das UN.

Prostaglandins Leukot Essent Fatty Acids. 1995 Jun;52(6):387-91.PMID: 7644560 [PubMed - indexed for MEDLINE]Related articles

Long-chain polyunsaturated fatty acids interact with nitric oxide, superoxide anion, and transforming growth factor-beta to prevent human essential hypertension.

Das UN.

Eur J Clin Nutr. 2004 Feb;58(2):195-203. Review.PMID: 14749737 [PubMed - indexed for MEDLINE]Related articles

[Biology of essential fatty acids (EFA)]

Dobryniewski J, Szajda SD, Waszkiewicz N, Zwierz K.

Przegl Lek. 2007;64(2):91-9. Review. Polish. PMID: 17892040 [PubMed - indexed for MEDLINE]Related articles

Comparison of mechanism and functional effects of magnesium and statin pharmaceuticals.

Rosanoff A, Seelig MS.

J Am Coll Nutr. 2004 Oct;23(5):501S-505S. Review.PMID: 15466951 [PubMed - indexed for MEDLINE]Related articlesFree article

Folic acid says NO to vascular diseases.

Das UN.

Nutrition. 2003 Jul-Aug;19(7-8):686-92. Review.PMID: 12831960 [PubMed - indexed for MEDLINE]Related articles

Effects of a polypill (Polycap) on risk factors in middle-aged individuals without cardiovascular disease (TIPS): a phase II, double-blind, randomised trial.

Indian Polycap Study (TIPS), Yusuf S, Pais P, Afzal R, Xavier D, Teo K, Eikelboom J, Sigamani A, Mohan V, Gupta R, Thomas N.

Lancet. 2009 Apr 18;373(9672):1341-51. Epub 2009 Mar 30.PMID: 19339045 [PubMed - indexed for MEDLINE]Related articles