PubMed

Cortisol release from adipose tissue by 11beta-hydroxysteroid dehydrogenase type 1 in humans.

Stimson RH, Andersson J, Andrew R, Redhead DN, Karpe F, Hayes PC, Olsson T, Walker BR.

Diabetes. 2009 Jan;58(1):46-53. Epub 2008 Oct 13.PMID: 18852329 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of peroxisome proliferator-activated receptor-alpha and -gamma agonists on 11beta-hydroxysteroid dehydrogenase type 1 in subcutaneous adipose tissue in men.

Wake DJ, Stimson RH, Tan GD, Homer NZ, Andrew R, Karpe F, Walker BR.

J Clin Endocrinol Metab. 2007 May;92(5):1848-56. Epub 2007 Feb 27.PMID: 17327378 [PubMed - indexed for MEDLINE]Related articlesFree article

Extra-adrenal regeneration of glucocorticoids by 11beta-hydroxysteroid dehydrogenase type 1: physiological regulator and pharmacological target for energy partitioning.

Walker BR.

Proc Nutr Soc. 2007 Feb;66(1):1-8.PMID: 17343766 [PubMed - indexed for MEDLINE]Related articles

Lack of regulation of 11beta-hydroxysteroid dehydrogenase type 1 during short-term manipulation of GH in patients with hypopituitarism.

Sigurjonsdottir HA, Andrew R, Stimson RH, Johannsson G, Walker BR.

Eur J Endocrinol. 2009 Sep;161(3):375-80. Epub 2009 Jun 23.PMID: 19549748 [PubMed - indexed for MEDLINE]Related articlesFree article

Tissue-specific dysregulation of cortisol metabolism in human obesity.

Rask E, Olsson T, Söderberg S, Andrew R, Livingstone DE, Johnson O, Walker BR.

J Clin Endocrinol Metab. 2001 Mar;86(3):1418-21.PMID: 11238541 [PubMed - indexed for MEDLINE]Related articlesFree article

11beta-hydroxysteroid dehydrogenase type 1 and obesity.

Morton NM, Seckl JR.

Front Horm Res. 2008;36:146-64. Review.PMID: 18230901 [PubMed - indexed for MEDLINE]Related articles

Inhibition of 11beta-hydroxysteroid dehydrogenase type 1 activity in vivo limits glucocorticoid exposure to human adipose tissue and decreases lipolysis.

Tomlinson JW, Sherlock M, Hughes B, Hughes SV, Kilvington F, Bartlett W, Courtney R, Rejto P, Carley W, Stewart PM.

J Clin Endocrinol Metab. 2007 Mar;92(3):857-64. Epub 2007 Jan 2.PMID: 17200165 [PubMed - indexed for MEDLINE]Related articlesFree article

11Beta-HSD type 1 expression in human adipose tissue: impact of gender, obesity, and fat localization.

Paulsen SK, Pedersen SB, Fisker S, Richelsen B.

Obesity (Silver Spring). 2007 Aug;15(8):1954-60.PMID: 17712112 [PubMed - indexed for MEDLINE]Related articles

The contribution of visceral adipose tissue to splanchnic cortisol production in healthy humans.

Andrew R, Westerbacka J, Wahren J, Yki-Järvinen H, Walker BR.

Diabetes. 2005 May;54(5):1364-70.PMID: 15855321 [PubMed - indexed for MEDLINE]Related articlesFree article

Expression of 11beta-hydroxysteroid dehydrogenase type 1 in adipose tissue is not increased in human obesity.

Tomlinson JW, Sinha B, Bujalska I, Hewison M, Stewart PM.

J Clin Endocrinol Metab. 2002 Dec;87(12):5630-5.PMID: 12466364 [PubMed - indexed for MEDLINE]Related articlesFree article

Tissue-specific changes in peripheral cortisol metabolism in obese women: increased adipose 11beta-hydroxysteroid dehydrogenase type 1 activity.

Rask E, Walker BR, Söderberg S, Livingstone DE, Eliasson M, Johnson O, Andrew R, Olsson T.

J Clin Endocrinol Metab. 2002 Jul;87(7):3330-6.PMID: 12107245 [PubMed - indexed for MEDLINE]Related articlesFree article

Increased in vivo regeneration of cortisol in adipose tissue in human obesity and effects of the 11beta-hydroxysteroid dehydrogenase type 1 inhibitor carbenoxolone.

Sandeep TC, Andrew R, Homer NZ, Andrews RC, Smith K, Walker BR.

Diabetes. 2005 Mar;54(3):872-9.PMID: 15734867 [PubMed - indexed for MEDLINE]Related articlesFree article

Type 2 diabetes and metabolic syndrome are associated with increased expression of 11beta-hydroxysteroid dehydrogenase 1 in obese subjects.

Alberti L, Girola A, Gilardini L, Conti A, Cattaldo S, Micheletto G, Invitti C.

Int J Obes (Lond). 2007 Dec;31(12):1826-31. Epub 2007 Jun 26.PMID: 17593901 [PubMed - indexed for MEDLINE]Related articles

Impaired glucose tolerance and insulin resistance are associated with increased adipose 11beta-hydroxysteroid dehydrogenase type 1 expression and elevated hepatic 5alpha-reductase activity.

Tomlinson JW, Finney J, Gay C, Hughes BA, Hughes SV, Stewart PM.

Diabetes. 2008 Oct;57(10):2652-60. Epub 2008 Jul 15.PMID: 18633104 [PubMed - indexed for MEDLINE]Related articlesFree article

In the lipodystrophy associated with highly active antiretroviral therapy, pseudo-Cushing's syndrome is associated with increased regeneration of cortisol by 11beta-hydroxysteroid dehydrogenase type 1 in adipose tissue.

Sutinen J, Kannisto K, Korsheninnikova E, Nyman T, Ehrenborg E, Andrew R, Wake DJ, Hamsten A, Walker BR, Yki-Järvinen H.

Diabetologia. 2004 Oct;47(10):1668-71. Epub 2004 Sep 29.PMID: 15455200 [PubMed - indexed for MEDLINE]Related articles

Expression and activity of 11beta-hydroxysteroid dehydrogenase type 1 enzyme in subcutaneous and visceral adipose tissue of prepubertal children.

Mericq V, Medina P, Bouwman C, Johnson MC, Godoy J, López T, Iñiguez G.

Horm Res. 2009;71(2):89-93. Epub 2009 Jan 8.PMID: 19129713 [PubMed - indexed for MEDLINE]Related articles

Regulation of 11beta-HSD genes in human adipose tissue: influence of central obesity and weight loss.

Engeli S, Böhnke J, Feldpausch M, Gorzelniak K, Heintze U, Janke J, Luft FC, Sharma AM.

Obes Res. 2004 Jan;12(1):9-17.PMID: 14742837 [PubMed - indexed for MEDLINE]Related articles

Upregulation of adipose 11-beta-hydroxysteroid dehydrogenase type 1 expression in ovariectomized rats is due to obesity rather than lack of estrogen.

Paulsen SK, Nielsen MP, Richelsen B, Bruun JM, Flyvbjerg A, Pedersen SB.

Obesity (Silver Spring). 2008 Apr;16(4):731-5. Epub 2008 Jan 31.PMID: 18379559 [PubMed - indexed for MEDLINE]Related articles

Growth hormone, insulin-like growth factor-I and the cortisol-cortisone shuttle.

Stewart PM, Toogood AA, Tomlinson JW.

Horm Res. 2001;56 Suppl 1:1-6. Review.PMID: 11786677 [PubMed - indexed for MEDLINE]Related articles

11beta-Hydroxysteroid dehydrogenase Type 1: genetic polymorphisms are associated with Type 2 diabetes in Pima Indians independently of obesity and expression in adipocyte and muscle.

Nair S, Lee YH, Lindsay RS, Walker BR, Tataranni PA, Bogardus C, Baier LJ, Permana PA.

Diabetologia. 2004 Jun;47(6):1088-95. Epub 2004 May 20.PMID: 15156315 [PubMed - indexed for MEDLINE]Related articles